Heatstroke is the most hazardous condition in a spectrum of illnesses progressing from heat exhaustion to heatstroke, in which a shared finding is hyperthermia (i.e. the rise in core body temperature when heat accumulation overrides heat dissipation during exercise or exposure to environmental heat…
Pain is "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or [is] described in terms of such damage" when there is no physical derangement. The function of pain is to protect the body by making the organism aware of damaging events and to promote…
The majority of burn injuries are minor and either do not require treatment or can be treated by any caregiver. More severe burns can result in clinically significant morbidity and, unless treated appropriately, can lead to severe scarring. Major burns lead to a profound systemic response that has…
Foreword. This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors’ clinical recommendations. Stage. An 18-year-old…
In the time it takes to read this article, at least one person in the United States will have died from an opioid overdose. From 1999 through 2017, more than 700,000 U.S. residents died from a drug overdose; the majority of these events involved an opioid. Among persons between the ages of 24 and…
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