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Αλέξανδρος Γ. Σφακιανάκης

Saturday, June 29, 2019

A New Method for Percutaneous Drug Delivery by Thermo‐Mechanical Fractional Injury
Background and Objectives Percutaneous drug delivery (PDD) is a means of increasing the uptake of topically applied agents into the skin. Successful delivery of a photosensitizer into the skin is an important factor for effective photodynamic therapy. To evaluate the efficacy of pretreatment by thermomechanical fractional injury (TMFI) (Tixel®, Novoxel®, Israel) at low‐energy settings in increasing the permeability of the skin to a known hydrophilic‐photosensitizer medication, 5‐amino‐levulinic‐acid...
Lasers in Surgery and Medicine
1h
Intraclass Correlations of Measured Magnetic Resonance Imaging Volumes of Laser Interstitial Thermal Therapy‐Treated High‐Grade Gliomas
Background and Objectives Laser interstitial thermal therapy (LITT) is a minimally invasive therapeutic option for the treatment of brain tumors. Previous studies have quantitatively followed the ablated volumes of high‐grade gliomas. Reported treatment volumes range from 28% to 100%, with no reported interobserver analysis. Because these volumes are subjectively measured, it is necessary to establish concordance between clinicians. Study Design/Materials and Methods Utilizing Brainlab tumor...
Lasers in Surgery and Medicine
1h

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