Publication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Long Xu, Yong Zhang, Renjie Zhang, Huaqing Zhang, Peiwen Song, Tai Ma, Yue Li, Xian Wang, Xin Hou, Qun Li, Jiegou Xu, Xiaoping Gao, Cailiang ShenAbstractBackgroundThe precise role of innate immune responses in the early stage of traumatic spinal cord injury (SCI), especially those mediated by natural killer (NK) cells, is poorly understood.MethodsThe frequency and phenotype of NK cells from traumatic SCI...
Publication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Lingling Sun, Yali Chen, Xiaoyan Shen, Tanzhen Xu, Yanyan Yin, Han Zhang, Shixin Ding, Yan Zhao, Yuling Zhang, Yajun Guan, Weizu LiAbstractGlucocorticoids (GCs) exposure has deleterious alteration on the structure and function in hippocampal neurons. NADPH oxidase 2 (NOX2) is a major contributor to oxidative stress in neurological diseases, and NLRP1 inflammasome can be activated in response to oxidative...
Publication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Laércia K.D. Paiva Ferreira, Larissa A.M. Paiva Ferreira, Talissa M. Monteiro, Grasiela Costa Bezerra, Larissa Rodrigues Bernardo, Marcia Regina PiuvezamAbstractCombined allergic rhinitis and asthma syndrome (CARAS) is a concept of “one airway – one disease” or “unified airway disease “. The upper and lower airway inflammation characterizes allergic rhinitis and asthma, respectively and both diseases have...
Publication date: September 2019Source: International Immunopharmacology, Volume 74Author(s): Shenghui Yang, Yibing Yin, Wenchun Xu, Xuemei Zhang, Yue Gao, Hongyi Liao, Xuexue Hu, Jian Wang, Hong WangAbstractType I interferon (IFN) is indispensable for antiviral immunity, but its role in bacterial infections is controversial and not fully described. Nontypeable Haemophilus influenzae (NTHi) is one of the most common bacterial pathogens in patients with chronic obstructive pulmonary disease (COPD)....
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