Blog Archive

Αλέξανδρος Γ. Σφακιανάκης

Tuesday, April 9, 2019

Endocrinology

The use of Medical Identification Jewellery in Adults with Adrenal Insufficiency in Australia
SummaryObjectiveHydrocortisone stress dosing during illness can prevent adrenal crises (AC) in patients with adrenal insufficiency (AI). When patients cannot communicate, medical identification jewellery may facilitate parenteral hydrocortisone provision but patient adoption rates are not known.DesignA cross‐sectional analysis of Australian medical identification jewellery subscription data.PatientsPatients with AI aged 20 years and over with an active subscription to a large medical jewellery...
Clinical Endocrinology
Tue Apr 09, 2019 12:06
The medical treatment with pasireotide in Cushing's disease: an Italian multicentre experience based on "real-world evidence"
Abstract A phase III study has demonstrated that 6-month pasireotide treatment induced disease control with good safety in 15–26% of patients with Cushing's disease (CD). The aim of the current study was to evaluate the 6-month efficacy and safety of pasireotide treatment according to the real-world evidence. Thirty-two CD patients started pasireotide at the dose of 600 µg twice a day (bid) and with the chance of up-titration to 900 µg bid, or down-titration to 450 or 300 µg bid,...
International journal of basic and clinical endocrinology
Tue Apr 09, 2019 03:00
The next step after anti-osteoporotic drug discontinuation: an up-to-date review of sequential treatment
Abstract Several antiresorptive drugs, like bisphosphonates and denosumab, are currently available for the treatment of osteoporosis due to their evidenced efficacy in reducing fracture risk at mid-term. Osteoanabolic therapies, like teriparatide, whose treatment duration is limited to 2 years, have also shown efficacy in the reduction of fracture risk. However, depending on the severity of osteoporosis and the presence of other associated risk factors for fracture, some patients...
International journal of basic and clinical endocrinology
Mon Apr 08, 2019 03:00
Cellular markers in corticotroph adenomas correlate with hormones–concerns on interpretation
International journal of basic and clinical endocrinology
Mon Apr 08, 2019 03:00
Ketogenic diet compromises vertebral microstructure and biomechanical characteristics in mice
Abstract Ketogenic diet (KD) compromised the microstructure of cancellous bone and the mechanical property in the appendicular bone of mice, while the effects of KD on the axial bone have not been reported. This study aimed to compare the changes in the microstructure and mechanical properties of the forth lumbar (L4) vertebra in KD and ovariectomized (OVX) mice. Forty eight-week-old female C57BL/6J mice were assigned into four groups: SD (standard diet) + Sham, SD + OVX, KD + Sham,...
Journal of Bone and Mineral Metabolism
Tue Apr 09, 2019 03:00
Warfarin calcifies human aortic valve interstitial cells at high-phosphate conditions via pregnane X receptor
Abstract Warfarin, a vitamin K antagonist, is the most common anticoagulant used to prevent thromboembolisms associated with atrial fibrillation or following valvular surgery. Although several studies have revealed that long-term warfarin use accelerates aortic valve calcification and the development of aortic stenosis (AS), the detailed mechanism for this phenomenon remains unclear. Therefore, our aim was twofold: to establish the conditions for warfarin-induced calcification...
Journal of Bone and Mineral Metabolism
Mon Apr 08, 2019 03:00
Adherence to growth hormone (GH) therapy in naïve to treatment GH-deficient children: data of the Italian Cohort from the Easypod Connect Observational Study (ECOS)
Abstract Background With the use of non-objective measurement, adherence to growth hormone (GH) therapy has been reported suboptimal in a large proportion of patients, and poor adherence has been shown to affect short-term growth response in patients receiving GH treatment. Objective The Easypod™ electronic device allows objective measurement of adherence....
Journal of Endocrinological Investigation
Tue Apr 09, 2019 03:00
Surveillance of patients with differentiated thyroid cancer and indeterminate response: a longitudinal study on basal thyroglobulin trend
Abstract Purpose This is a longitudinal study of retrospective data aimed at verifying whether repeated measurements of serum non-stimulated thyroglobulin (Tg) allow the prediction of persistent disease in patients with differentiated thyroid cancer (DTC) and indeterminate response. Methods We examined 145 DTC patients with indeterminate response to therapy...
Journal of Endocrinological Investigation
Mon Apr 08, 2019 03:00
Evaluation of the NOX5 protein expression and oxidative stress in sperm from asthenozoospermic men compared to normozoospermic men
Abstract Purpose NADPH oxidase 5 (NOX5), the main isoform of NOX in spermatozoa, has been recognized as the main active generators of reactive oxygen species (ROS), including superoxide anion (O 2−.) and hydrogen peroxide (H2O2). ROS have been shown to play important roles in many physiological and pathological conditions in spermatozoa. The present study aims to investigate the alterations of NOX5 protein expression...
Journal of Endocrinological Investigation
Mon Apr 08, 2019 03:00
Frontmatter
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: i-iv
Journal of Pediatric Endocrinology and Metabolism.
Sat Apr 06, 2019 03:00
The importance of anthropological methods in the diagnosis of rare diseases
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 311-320
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 27, 2019 02:00
PON1 arylesterase activity, HDL functionality and their correlation in malnourished children
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 321-326
Journal of Pediatric Endocrinology and Metabolism.
Fri Mar 15, 2019 02:00
Prevalence of dyslipidemia and factors affecting dyslipidemia in young adults with type 1 diabetes: evaluation of statin prescribing
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 327-334
Journal of Pediatric Endocrinology and Metabolism.
Tue Mar 12, 2019 02:00
Myocardial dysfunction in relation to serum thiamine levels in children with diabetic ketoacidosis
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 335-340
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 13, 2019 02:00
Evaluation of long-term follow-up and methimazole therapy outcomes of pediatric Graves' disease: a single-center experience
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 341-346
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 13, 2019 02:00
Endocrine consequences of neuroblastoma treatment in children: 20 years' experience of a single center
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 347-354
Journal of Pediatric Endocrinology and Metabolism.
Fri Mar 15, 2019 02:00
Analysis of diabetes-associated autoantibodies in children and adolescents with autoimmune thyroid diseases
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 355-361
Journal of Pediatric Endocrinology and Metabolism.
Sat Mar 23, 2019 02:00
Atypical presentation of Leydig cell tumour in three prepubertal patients: diagnosis, treatment and outcomes
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 369-374
Journal of Pediatric Endocrinology and Metabolism.
Fri Mar 15, 2019 02:00
Comparing the validity of continuous metabolic syndrome risk scores for predicting pediatric metabolic syndrome: the CASPIAN-V study
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 383-389
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 13, 2019 02:00
Primary pigmented nodular adrenocortical disease (PPNAD): single centre experience
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 391-397
Journal of Pediatric Endocrinology and Metabolism.
Fri Mar 15, 2019 02:00
Classical galactosemia patients can achieve high IQ scores
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 399-401
Journal of Pediatric Endocrinology and Metabolism.
Fri Mar 15, 2019 02:00
A case report and literature review of monoallelic mutation of GHR
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 415-419
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 20, 2019 02:00
Pitfalls in the diagnosis of insulin autoimmune syndrome (Hirata's disease) in a hypoglycemic child: a case report and review of the literature
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 421-428
Journal of Pediatric Endocrinology and Metabolism.
Wed Mar 13, 2019 02:00