Medicine by Alexandros G. Sfakianakisnoreply@blogger.com (Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,) ClinicalConnection.com New Clinical TrialsFemales With End-Stage Renal Impairment not on Dialysis - Anaheim CAClick image to enlargeLocal doctors are conducting a clinical trial to evaluate an antifungal medication in female participants with end-stage renal function not on dialysis.ClinicalConnection.com...
Wed Mar 04, 2020 10:03
pubmed: philosophy for medic...Effect of different therapeutic strategies on the clinical outcome of asymptomatic intralobar pulmonary sequestration.Related ArticlesEffect of different therapeutic strategies on the clinical outcome of asymptomatic intralobar pulmonary sequestration. Interact Cardiovasc Thorac Surg. 2019 11 01;29(5):706-713 Authors: Li XK, Luo J, Wu WJ, Cong ZZ, Xu Y, Hua TT, Shao CY, Ji SG, Diao YF, Liu KC, Qiang Y, Zhou H, Jiang ZS, Shen Y Abstract OBJECTIVES: Pulmonary sequestration...
Wed Mar 04, 2020 09:57
Laryngology and otologyCoblation versus cold dissection in paediatric tonsillectomy: a systematic review and meta-analysis.Related ArticlesCoblation versus cold dissection in paediatric tonsillectomy: a systematic review and meta-analysis. J Laryngol Otol. 2020 Mar 02;:1-8 Authors: Ahmad MU, Wardak AN, Hampton T, Siddiqui MRS, Street I Abstract BACKGROUND: Cold dissection is the most commonly used tonsillectomy technique, with low post-operative haemorrhage rates. Coblation is an alternative technique...
Wed Mar 04, 2020 09:56
Head and NeckIn silico analysis of a novel causative mutation in Cadherin23 gene identified in an Omani family with hearing loss.Related ArticlesIn silico analysis of a novel causative mutation in Cadherin23 gene identified in an Omani family with hearing loss. J Genet Eng Biotechnol. 2020 Mar 02;18(1):8 Authors: Al-Kindi MN, Al-Khabouri MJ, Al-Lamki KA, Palombo F, Pippucci T, Romeo G, Al-Wardy NM Abstract BACKGROUND: Hereditary hearing loss is a heterogeneous group of complex disorders with an...
Wed Mar 04, 2020 09:44
Head and Neck[Statement of the German Society of Otorhinolaryngology, Head and Neck Surgery on the execution of a tonsillotomy].Related Articles[Statement of the German Society of Otorhinolaryngology, Head and Neck Surgery on the execution of a tonsillotomy]. Laryngorhinootologie. 2020 Mar;99(3):176-180 Authors: Guntinas-Lichius O, Windfuhr J, Deitmer T, Delank KW PMID: 32120440 [PubMed - as supplied by publisher]Head and NeckTue Mar 03, 2020 14:45Essential characterisation of human papillomavirus...
Wed Mar 04, 2020 09:42
MedWorm ENT & OMF ResearchTraumatologie des Gesichtssch ädels im KindesalterLaryngo-Rhino-Otol 2020; 99: 155-165 DOI: 10.1055/a-1071-2061Frakturen des Gesichtsschädels sind im Kindesalter aufgrund anatomischer Besonderheiten und unterschiedlicher Kausalitäten deutlich seltener als im Erwachsenenalter. Die Versorgung von sich im Wachstum befindlichen Gesichtsschädelknochen stellt den behandelnden Arzt oft vor eine große Herausforderung und setzt eine genaue Kenntnis der kindlichen Anatomie voraus....
Wed Mar 04, 2020 09:41
European Journal of Vascular & Endovascular Surgery - Articles in PressLanding Zone Remodelling after Endovascular Repair of Dissected Descending AortaThe aim of this study was to determine geometric changes in the proximal and distal aortic landing zones after thoracic endovascular aortic repair (TEVAR) for acute descending aortic dissection.European Journal of Vascular & Endovascular Surgery - Articles in PressTue Mar 03, 2020 02:00Mark above section as read Journal of Clinical EpidemiologyQuality...
Wed Mar 04, 2020 09:37
InflammationZNRF3 Regulates Collagen-Induced Arthritis Through NF-kB and Wnt PathwaysAbstractAlthough the E3 ubiquitin ligase Zinc and ring finger 3 (ZNRF3) negatively regulates the Wnt signaling pathway, its function in rheumatoid arthritis (RA) is elusive. Here, the effects and the mechanism of ZNRF3 on a mouse model of collagen-induced arthritis (CIA) and human fibroblast-like synoviocytes (FLS) obtained from RA patients were determined. Our results showed that ZNRF3 was highly expressed in tissues...
Wed Mar 04, 2020 09:36
The Lancet Neurology[Series] Evidence-based support for autistic people across the lifespan: maximising potential, minimising barriers, and optimising the person–environment fitAutism is both a medical condition that gives rise to disability and an example of human variation that is characterised by neurological and cognitive differences. The goal of evidence-based intervention and support is to alleviate distress, improve adaptation, and promote wellbeing. Support should be collaborative, with...
Wed Mar 04, 2020 09:34
Journal of Experimental and Clinical Cancer ResearchCorrection to: The interplay between HIF-1 α and noncoding RNAs in cancerIn the original publication of this manuscript [1], Fig. 2 contains incorrect labels and feedback loops. The revised version of Fig. 2 is shown below. (Source: Journal of Experimental and Clinical Cancer Research)Journal of Experimental and Clinical Cancer ResearchTue Mar 03, 2020 01:00FKBP9 promotes the malignant behavior of glioblastoma cells and confers resistance to endoplasmic...
Wed Mar 04, 2020 09:33
Latest ResultsContrasting effects of iron reduction on thionation of diphenylarsinic acid in a biostimulated AcrisolAbstract Diphenylarsinic acid (DPAA) is an emerging phenylarsenic compound derived from chemical warfare agents. It has been suggested that biostimulation of sulfate reduction decreases the concentrations of DPAA in soils. However, biostimulation often induces Fe(III) reduction which may affect the mobility and thereby the transformation of DPAA. Here, a soil incubation experiment...
Wed Mar 04, 2020 09:32
pubmed dermatol clin [jour...Incorporating Lesbian, Gay, Bisexual, and Transgender Training into a Residency Program.Related ArticlesIncorporating Lesbian, Gay, Bisexual, and Transgender Training into a Residency Program. Dermatol Clin. 2020 Apr;38(2):285-292 Authors: Fakhoury JW, Daveluy S Abstract Lesbian, gay, bisexual, and transgender (LGBT) patients experience vast health care disparities. Numerous government and professional organizations have attempted to address these disparities by calling...
Wed Mar 04, 2020 09:31
Earth and environmental sciences : nature.com subject feedsChaos in disease outbreaks among preyEarth and environmental sciences : nature.com subject feedsTue Mar 03, 2020 02:00Confirmation of the shell-boring oyster parasite Polydora websteri (Polychaeta: Spionidae) in Washington State, USAEarth and environmental sciences : nature.com subject feedsTue Mar 03, 2020 02:00Destination Uranus! Rare chance to reach ice giants excites scientistsEarth and environmental sciences : nature.com subject feedsTue...
Wed Mar 04, 2020 09:30
International Journal of Molecular SciencesIJMS, Vol. 21, Pages 1725: Liraglutide Suppresses Tau Hyperphosphorylation, Amyloid Beta Accumulation through Regulating Neuronal Insulin Signaling and BACE-1 ActivityIJMS, Vol. 21, Pages 1725: Liraglutide Suppresses Tau Hyperphosphorylation, Amyloid Beta Accumulation through Regulating Neuronal Insulin Signaling and BACE-1 Activity International Journal of Molecular Sciences doi: 10.3390/ijms21051725 Authors: Salinee Jantrapirom Wutigri Nimlamool Nipon...
Wed Mar 04, 2020 09:29
Latest ResultsPredictors of the regional variation of prostatectomy or radiotherapy: evidence from German cancer registriesAbstract Objective To assess the association of public health parameters with the regional variation in the initial treatment for prostate cancer. Methods We used data from German epidemiologic cancer registries for the years 2009–2013. Presence of a certified cancer center, a radiotherapy and/or urology institution, the district-specific GDP, and population...Latest Results02:00Mark...
Wed Mar 04, 2020 09:28
Wiley: EFSA Journal: Table of ContentsStatement on the dietary exposure assessment for the temporary maximum residue levels for chlordecone in certain products of animal originAbstract In accordance with Article 43 of Regulation (EC) No 396/2005, the European Commission requested EFSA to carry out a consumer exposure assessment in relation to the maximum residue levels (MRLs) for chlordecone in products of animal origin recommended by the French Agency for Food, Environmental and Occupational Health...
Wed Mar 04, 2020 09:27
Latest Results for European RadiologyFeasibility of shear wave sonoelastography to detect endoleak and evaluate thrombus organization after endovascular repair of abdominal aortic aneurysmAbstract Purpose To investigate the feasibility of shear wave sonoelastography (SWS) for endoleak detection and thrombus characterization of abdominal aortic aneurysm (AAA) after endovascular repair (EVAR). Materials and methods Participants who underwent EVAR were prospectively recruited between November 2014...
Wed Mar 04, 2020 09:25
MedWorm Cancer & Oncology Clinical TrialsStudy to Evaluate the Efficacy and Safety of SHR6390 Combined With Pyrotinib in HER2+ Advanced Breast CancerCondition: Metastatic Breast Cancer Interventions: Drug: Pyrotinib; Drug: SHR6390 Sponsors: Henan Cancer Hospital; Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.MedWorm...
Wed Mar 04, 2020 09:24
Journal of Surgical Case Reports - current issueA benign, low-grade myofibroblastic lesion mimicking a sarcomaAbstractBenign myofibroblastic lesions can clinically and histologically be mistaken for sarcoma. Excessive and potentially disfiguring surgical treatment can be avoided by ruling out malignancy. We present the case of a low-grade, myofibroblastic lesion of the lip, which shows how detailed clinical examination rather than reliance on histopathological information alone helped to achieve...
Wed Mar 04, 2020 09:23
Latest Results for Drugs in RPhase I Pharmacokinetic Study of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in Healthy Adult and Adolescent PopulationsAbstract Introduction A fixed-dose combination (FDC) of ibuprofen and acetaminophen has been developed that provides greater analgesic efficacy than either agent alone at the same doses without increasing the risk for adverse events. Methods We report three clinical phase I studies designed to assess the pharmacokinetics (PK) of the FDC of...
Wed Mar 04, 2020 09:22
Frontiers in Psychology | New and Recent ArticlesThe Role of Moral Injury in PTSD Among Law Enforcement Officers: A Brief ReportExposure to critical incidents and hence potentially traumatic events is endemic in law enforcement. The study of law enforcement officers' experience of moral injury and their exposure to potentially morally injurious incidents, and research on moral injury's relationship with different forms of traumatization (e.g. compassion fatigue, post-traumatic stress disorder) are...
Wed Mar 04, 2020 09:21
International ImmunopharmacologyCorrigendum to "Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis" [Int. Immunopharmacol. 77 (2019) 105968].Corrigendum to "Tanshinone IIA ameliorates the bleomycin-induced endothelial-to-mesenchymal transition via the Akt/mTOR/p70S6K pathway in a murine model of systemic sclerosis" [Int. Immunopharmacol. 77 (2019) 105968]. Int Immunopharmacol. 2020 Feb 27;:106318...
Wed Mar 04, 2020 09:20
MedWorm Cancer & Oncology ResearchGSE128822 High-dimensional single cell analysis reveals an effector Treg molecular program that correlates with lung cancer progressionContributors : Giorgia Alvisi ; Simone Puccio ; Jolanda Brummelman ; Elisa Paoluzzi Tomada ; Emilia Mazza ; Enrico LugliSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensAnti-tumor immune responses are counteracted by CD4+ regulatory T (Treg) cells in the tumor micronenvironment, but the molecular...
Wed Mar 04, 2020 09:18
Latest Results for Cell and Tissue ResearchEvolving challenges to model human diseases for translational researchAbstract Animal models are a significant component of biomedical research and play an important role in translational studies. Traditionally, rodent models have been the mainstay and principal choice of researchers but in recent years, there have been significant changes in the landscape of animal modeling. For example, newer techniques have greatly expanded the use and successful application...
Wed Mar 04, 2020 09:17
Distinct trajectories of moderate to vigorous physical activity and sedentary behavior following a breast cancer diagnosis: the Pathways Study: AbstractPurposeTo identify distinct trajectories of total moderate-to-vigorous physical activity (MVPA) and sedentary behavior following a breast cancer diagnosis and their correlates.MethodsThe analysis examined 3000 female breast cancer survivors within Kaiser Permanente Northern California between 2006 and 2013. Self-reported time spent on total MVPA and...
Wed Mar 04, 2020 09:16
Cancer Prevention Research current issueNavigating the Intersection between Genomic Research and Clinical PracticeThe Risk Assessment Program (RAP) at Fox Chase Cancer Center (Philadelphia, PA) is a multi-generational prospective cohort, enhanced for personal and family history of cancer, consisting of over 10,000 individuals for whom data on personal and family history of cancer, risk factors, genetic and genomic data, health behaviors, and biospecimens are available. The RAP has a broad research...
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Journal of Pediatric Endocrinology and Metabolism.Oral health status of children with phenylketonuriaJournal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 33Issue: 3Pages: 361-365Journal of Pediatric Endocrinology and Metabolism.Wed Feb 12, 2020 02:00Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatallyJournal Name: Journal of Pediatric Endocrinology and MetabolismVolume:...
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J Neural EngAlpha down-regulation neurofeedback training effects on implicit motor learning and consolidation.Related ArticlesAlpha down-regulation neurofeedback training effects on implicit motor learning and consolidation. J Neural Eng. 2020 Mar 03;: Authors: Nan W, Yang L, Wan F, Zhu FF, Hu Y Abstract OBJECTIVE: Implicit motor learning, which is a non-conscious form of learning characterized by motor performance improvement with practice, plays an essential role in various daily activities. Earlier...
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Hellenic Anticancer InstituteImpact of Extent of Lymphadenectomy on Survival in Patients With Endometrial Cancer: A Matched Cohort StudyBackground/Aim: This study aimed to determine whether a pelvic and para-aortic lymphadenectomy (PPAL) improves survival compared with a pelvic lymphadenectomy (PL) in patients with endometrial cancer. Patients and Methods: Data from all women operated for endometrial cancer between 1998 and 2013 were extracted from the Surveillance, Epidemiology and End Results...
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Hellenic Anticancer InstituteImpact of Bevacizumab-containing Primary Treatment on Outcome of Recurrent Ovarian Cancer: An Italian StudyBackground/Aim: The aim of the study was to assess the outcome of advanced ovarian cancer patients who i) underwent primary surgery followed by carboplatin/paclitaxel–based chemotherapy with or without bevacizumab, ii) were in complete response after chemotherapy, iii) and subsequently recurred. Patients and Methods: The hospital records of 138 complete responders...
08:45
Evolutionary Biology News -- ScienceDailyApes' inner ears could hide clues to evolutionary history of hominoidsStudying the inner ear of apes and humans could uncover new information on our species' evolutionary relationships, suggests a new study.Evolutionary Biology News -- ScienceDailyTue Mar 03, 2020 18:33Mark above section as read Rare CancersPharmacokinetics and pharmacodynamics of ropinirole in patients with prolactinomas.Related ArticlesPharmacokinetics and pharmacodynamics of ropinirole...
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Radiation protection dosimetryRE-EVALUATION OF THE AIR KERMA PRIMARY STANDARD OF THE SMU IN 60Co AND 137Cs GAMMA RAY BEAMS.Related ArticlesRE-EVALUATION OF THE AIR KERMA PRIMARY STANDARD OF THE SMU IN 60Co AND 137Cs GAMMA RAY BEAMS. Radiat Prot Dosimetry. 2020 Mar 02;: Authors: Durný N Abstract The primary standard for air kerma of the Slovak Institute of Metrology (SMU) as a part of national standard of dosimetric quantities of gamma radiation NE028/02, based on cylindrical graphite walled cavity...
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Nature Communications - current - nature.com science feedsDisordered protein-graphene oxide co-assembly and supramolecular biofabrication of functional fluidic devicesNature Communications, Published online: 04 March 2020; doi:10.1038/s41467-020-14716-zSelf-organising systems have huge potential in device design and fabrication; however, demonstrations of this are limited. Here, the authors report on a combination of disordered proteins and graphene oxide which allows spatio-temporal patterning...
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Journal of Internal MedicineClinical and molecular insights into BCG immunotherapy for melanomaAbstract The incidence of cutaneous melanoma and the mortality rate of advanced melanoma patients continues to rise globally. Despite the recent success of immunotherapy including ipilimumab and pembrolizumab checkpoint inhibitors, a large proportion of patients are refractory to such treatment modalities. The application of mycobacteria such as Bacillus Calmette‐Guérin (BCG) in the treatment of various...
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Dysphagia - RehabilitationStudy protocol for a randomized controlled trial: prophylactic swallowing exercises in head-and-neck cancer patients treated with (chemo)radiotherapy (PRESTO trial).Related ArticlesStudy protocol for a randomized controlled trial: prophylactic swallowing exercises in head-and-neck cancer patients treated with (chemo)radiotherapy (PRESTO trial). Trials. 2020 Mar 02;21(1):237 Authors: Baudelet M, Van den Steen L, Duprez F, De Bodt M, Deschuymer S, Goeleven A, Hutsebaut I,...
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pubmed: "proc natl acad sci ..."Proc Natl Acad Sci U S A"[jour]; +56 new citations56 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/03/04PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher...
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European Archives of Oto-Rhino-LaryngologyDipping and rotating: two maneuvers to achieve maximum magnification during indirect transnasal laryngoscopyAbstract Background Since many years, office-based flexible transnasal laryngoscopy is a common routine procedure. The development of new technical equipment such as high-definition cameras and flexible tip-chip endoscopes nowadays allows for much more precise examination than a few years ago. In contrast to rigid laryngoscopy, it is possible to move...
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ScienceDirect Publication: Pathology - Research and PracticeCancer associated fibroblasts as novel promising therapeutic targets in breast cancerPublication date: Available online 2 March 2020Source: Pathology - Research and PracticeAuthor(s): Sevda Salimifard, Ali Masjedi, Mohammad Hojjat-Farsangi, Ghasem Ghalamfarsa, Mahzad Irandoust, Gholamreza Azizi, Hamed Mohammadi, Mohammad Reza Keramati, Farhad Jadidi-NiaraghScienceDirect Publication: Pathology - Research and PracticeWed Mar 04, 2020 18:23Methylation...
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OEM Online FirstWork-related adverse respiratory health outcomes at a machine manufacturing facility with a cluster of bronchiolitis, alveolar ductitis and emphysema (BADE)ObjectivesFour machine manufacturing facility workers had a novel occupational lung disease of uncertain aetiology characterised by lymphocytic bronchiolitis, alveolar ductitis and emphysema (BADE). We aimed to evaluate current workers' respiratory health in relation to job category and relative exposure to endotoxin, which is...
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Experimental Brain ResearchTo step or to spring: the influence of state anxiety on perceptual judgements and executed actionAbstract Emotional state, in particular anxiety, has been shown to constrain perceptual judgement of action capabilities. However, whether anxiety also constrains actual behaviour is unknown. The current study, therefore, aimed to determine whether state anxiety constrained firstly perceptual judgements of action capabilities and secondly actual behaviour. To do this, we asked...
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American Journal of Clinical Oncology - Published Ahead-of-PrintGemcitabine Plus Cisplatin Chemotherapy Prolongs the Survival in Advanced Hilar Cholangiocarcinoma: A Large Multicenter StudyObjectives: Gemcitabine plus cisplatin (GC) is recommended as first-line treatment for advanced cholangiocarcinoma. We investigated the impact of GC in patients with unresectable hilar cholangiocarcinoma (HC) based on the time taken for effective biliary drainage (EBD). Materials and Methods: We retrospectively...
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Wiley: EFSA Journal: Table of ContentsScientific Opinion on Flavouring Group Evaluation 72, Revision 2 (FGE.72Rev2): consideration of aliphatic, branched‐chain saturated and unsaturated alcohols, aldehydes, acids and related esters evaluated by JECFA (61st, 68th and 69th meetings) and structurally related to flavouring substances in FGE.05Rev3Abstract The EFSA Panel on Food Additives and Flavourings was requested to evaluate 31 flavouring substances assigned to the Flavouring Group Evaluation 72...
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Journal of Endocrinological InvestigationPhosphate-sensing and regulatory mechanism of FGF23 productionAbstract Background Inorganic phosphate (Pi) is an essential mineral for human. Hypophosphatemia and hyperphosphatemia cause rickets/osteomalacia and ectopic calcification, respectively, indicating that serum Pi level needs to be regulated. Fibroblast growth factor (FGF) 23 is a principal hormone to regulate serum Pi level. FGF23 is produced by the bone, especially by the osteoblasts and osteocytes,...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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