The limited role of elective neck dissection in patients with cN0 salivary gland carcinoma.

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The limited role of elective neck dissection in patients with cN0 salivary gland carcinoma.

J Craniomaxillofac Surg. 2018 Nov 22;:

Authors: Qian K, Guo K, Zheng X, Sun W, Sun T, Chen L, Ma D, Wu Y, Ji Q, Wang Z

Abstract
PURPOSE: To evaluate whether elective neck dissection (END) was beneficial for cN0 patients with salivary gland carcinoma.
MATERIALS AND METHODS: The rates of regional failure-free survival and disease-free survival were calculated using Kaplan-Meier methods and Cox models. The risk factors for occult lymph node metastasis (OLNM) in cN0 patients undergoing END was analyzed using logistic regression. A nomogram was formulated to calculate the estimated probability of OLNM.
RESULTS: Neck dissection was performed in 84 patients (43.3%). OLNM was detected in eight of the patients who underwent END. During the follow-up period, regional recurrences involving cervical lymph nodes were found in 10 patients. Cox model analysis revealed that neck dissection was not related to regional failure-free survival and disease-free survival. Logistic regression analysis revealed that older age, neural symptoms, and positive adjacent lymph nodes were associated with OLNM. A nomogram comprising age, neural symptoms, and adjacent lymph nodes was developed to predict the risk of OLNM.
CONCLUSION: The incidence of OLNM was low in cN0 patients after detailed preoperative evaluations. There was no strong evidence supporting END as a conventional therapy in cN0 patients with salivary cancers. Our nomogram is a simple and practical instrument for strengthening the prediction of OLNM.

PMID: 30528947 [PubMed - as supplied by publisher]

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