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Αλέξανδρος Γ. Σφακιανάκης

Wednesday, December 12, 2018

[Pharmacology of non-opioid analgesics].

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[Pharmacology of non-opioid analgesics].

Schmerz. 2018 Dec 07;:

Authors: Schneider J, Kreutz R, Bolbrinker J

Abstract
Due to high prescription rates as well as the frequent use as over the counter drugs, it is of interest to consider non-opioid analgesics when evaluating the quality and appropriateness of a given overall medication. This article sums up the basic pharmacology and main adverse effects of these analgesics. Non-opioids can be further classified according to their additional mechanisms of action besides analgesia. High-dose acetylsalicylic acid, traditional nonsteroidal anti-inflammatory drugs, and coxibs exhibit antipyretic and anti-inflammatory properties. Acetaminophen and metamizole (dipyrone) are analgesics and antipyretic agents, while metamizole exhibits also spasmolytic effects. Capsaicin and intrathecal ziconotide are pure analgesics.

PMID: 30535850 [PubMed - as supplied by publisher]



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