The safety of povidone-iodine solution in tympanoplasty: a randomised, triple-blind, placebo-controlled study

xlomafota13 shared this article with you from Inoreader The safety of povidone-iodine solution in tympanoplasty: a randomised, triple-blind, placebo-controlled study Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Aug;41(4):377-382. doi: 10.14639/0392-100X-N1369. ABSTRACT OBJECTIVE: Nowadays, povidone-iodine is commonly used as a disinfectant in head and neck procedures. The present study investigated the effect of povidone-iodine, which is used as a disinfectant solution in tympanoplasty, on patients' hearing. METHODS: A povidone-iodine solution was used as disinfection in chronic otitis media patients undergoing tympanoplasty. In the interventio n group, 5% povidone-iodine, was applied to the external auditory canal and remained there for 10 minutes. In the control group, povidone-iodine was used but not allowed to enter the external auditory canal by inserting cotton wool into the canal. To evaluate the adverse effect of povidone-iodine on hearing, the bone conduction level was compared between groups at baseline and one month after exposure. RESULTS: Bone conduction levels at frequencies 500 Hz, 1 kHz, 2 kHz, 3 kHz, 4 kHz and 8 kHz and mean of bone conduction level in 500 Hz, 1 kHz and 2 kHz were measured and compared respectively between intervention and control group. No significant difference was seen between bone conduction levels of above frequencies and mean frequencies before and one month after surgery. (P-value = 0.321, 0.432, 0.219, 0.489, 0.61, 0.112, 0.324 respectively). CONCLUSIONS: According to the present study, currently available 5% povidone-iodine did not affect hearing and therefore, can be comfortably used for preparation and disinfection in otologic surgeries. PMID:34533542 | DOI:10.14639/0392-100X-N1369 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.