Surgical treatment for squamous cell carcinoma of the temporal bone: predictors of survival

xlomafota13 shared this article with you from Inoreader Surgical treatment for squamous cell carcinoma of the temporal bone: predictors of survival Via Acta Otorhinolaryngol Ital Acta Otorhinolaryngol Ital. 2021 Aug;41(4):308-316. doi: 10.14639/0392-100X-N1074. ABSTRACT OBJECTIVE: Evaluation of the management and survival in patients treated for temporal bone squamous cell carcinoma (TBSCC) in a tertiary referral centre. METHODS: Forty-nine patients underwent primary treatment for TBSCC. Thirty-six patients underwent a lateral temporal bone resection (LTBR) or subtotal temporal bone resection (STBR). Overall survival (OS) and disease-specific s urvival (DSS) analysis were assessed. RESULTS: Five-year OS of the 49 patients was 39%. Five-year OS of the 36 patients who underwent LTBR or STBR was 46%. Tumour-free margins were achieved in all patients with T1 and T2 disease, in 59% patients with T3 tumours and 0% patients with T4 disease. Five-year DSS was 85% for all T1/T2 tumours, 53% for T3 tumours and 0% for T4 tumours. Clear resection margins was the only significant predictor of DSS in our cohort. CONCLUSIONS: The mainstay of treatment for TBSCC is temporal bone resection with tumour free resection margins, with or without adjuvant radiotherapy. Survival is negatively influenced by non-radical resection. T1 and T2 tumours can be managed safely with LTBR. More advanced disease requires a more extensive resection, with a higher likelihood of non-radical resections and decreased survival rates. PMID:34533534 | DOI:10.14639/0392-100X-N1074 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.