Out of Phase: How IPMK Inhibits TFEB.

payth.elady61 shared this article with you from Inoreader Out of Phase: How IPMK Inhibits TFEB. Via pubmed: autophagy Out of Phase: How IPMK Inhibits TFEB. Dev Cell. 2020 Dec 07;55(5):517-519 Authors: Ferrari L, Martens S Abstract The expression of autophagy and lysosomal genes is coordinated by the transcription factor EB (TFEB). In this issue of Developmental Cell, Chen et al. identify an evolutionary conserved mode of TFEB regulation, which entails the inhibition of TFEB phase separation in the nucleus by inositol polyphosphate multikinase. PMID: 33290690 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.