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Αλέξανδρος Γ. Σφακιανάκης

Friday, December 7, 2018

Open-neck organ preservation surgery for hypopharyngeal cancer: indications, techniques, limits, and outcomes.

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Open-neck organ preservation surgery for hypopharyngeal cancer: indications, techniques, limits, and outcomes.

Curr Opin Otolaryngol Head Neck Surg. 2018 Nov 16;:

Authors: Bradley PJ, Liu L

Abstract
PURPOSE OF REVIEW: To appraise the practice and role of open-neck organ preserving surgery for hypopharyngeal squamous cell carcinoma and to update the current indications, techniques, limits, and outcomes.
RECENT FINDINGS: The role of primary surgery for hypopharyngeal carcinoma has shifted over the past two decades to primary nonsurgical management with the use of induction or concurrent chemoradiotherapy. The preferred and most suitable tumours for open-neck surgery are the small-volume T stage diseases, with small to medium-volume neck metastases, however such patients are exceedingly rare. Nonetheless, more advanced tumours with cartilage invasion, vocal cord paralysis, or located at piriform apex and postcricoid area, previously unsuitable for open-neck organ preserving surgery, can now be excised and repaired, minimizing morbidity and improving quality of patients' life. Much of this surgical progress has been developed by innovative surgeons using free tissue transfer, accurate placement surgery, reconstruction of a neoglottis, and perfecting the pharyngoesophageal anastomosis. Current practice of open-neck organ preserving surgery for hypopharyngeal carcinoma has been mainly reported in Asia: Korea, Taiwan, Japan, and China.
SUMMARY: There are some patients who are deemed unsuitable and/or unwilling for current treatment by nonsurgical approaches, and open-neck organ preserving laryngopharyngeal surgery may be a more suitable alternative than selecting a 'lesser or modified' chemo or bioradiotherapy regimen, resulting in a prolonged quantity and quality of life.

PMID: 30507694 [PubMed - as supplied by publisher]



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