In their randomized clinical trial in this issue of JAMA Otolaryngology–Head & Neck Surgery, Khan and colleagues investigated the use of variations of olfactory training (OT) in individuals with COVID-19–related olfactory loss and found no difference in olfactory improvement with the use of patient-preferred scents or the addition of visual aids compared with conventional OT. In the study, the authors randomized participants with long-term COVID-19 olfactory loss into 4 intervention arms: (1) unimodal conventional OT using the origin ally reported 4 odorants (rose, eucalyptus, lemon, clove), (2) unimodal patient-preferred OT with self-selection of 4 odorants, (3) bimodal conventional OT using visual aids, and (4) bimodal patient-preferred OT with the use of visual aids. There was an additional independent control cohort who underwent no treatment.
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