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Αλέξανδρος Γ. Σφακιανάκης

Thursday, June 3, 2021

Infiltrating ductal breast carcinoma with monoclonal gammopathy of undetermined significance: A case report

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World J Clin Cases. 2021 May 26;9(15):3675-3679. doi: 10.12998/wjcc.v9.i15.3675.

ABSTRACT

BACKGROUND: Infiltrating ductal breast carcinoma with monoclonal gammopathy of undetermined significance (MGUS) is rare and easily misdiagnosed. Most patients are first diagnosed with MGUS. We report a rare case of MGUS secondary to infiltrating ductal breast carcinoma. We also review the literature to analyze the clinical characteristics and diagnostic methods.

CASE SUMMARY: A 51-year-old woman underwent modified radical mastectomy for infiltrating ductal carcinoma of the right breast and was then treated with radiation and chemotherapy. A decreased platelet count was found on routine blood examination, and MGUS was subsequently diagnosed. This is the first report of the occurrence of MGUS after breast cancer surgery.

CONCLUSION: Vigilance is required to distinguish this rare comorbidity from breast plasmacytoma.

PMID:34046469 | PMC:PMC8130065 | DOI:10.12998/wjcc.v9.i15.3675

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