Cholesterol gallstones: Focusing on the role of interstitial Cajal-like cells

paythelady.612 shared this article with you from Inoreader Cholesterol gallstones: Focusing on the role of interstitial Cajal-like cells Μέσω pubmed: "world j clin cases"... World J Clin Cases. 2021 May 26;9(15):3498-3505. doi: 10.12998/wjcc.v9.i15.3498. ABSTRACT Cholesterol gallstone (CG) is a common, frequent biliary system disease in China, with a complex and multifactorial etiology. Declined gallbladder motility reportedly contributes to CG pathogenesis. Furthermore, interstitial Cajal-like cells (ICLCs) are reportedly present in human and guinea pig gallbladder tissue. ICLCs potentially contribute to the regulation of gallbladder motility, and aberrant conditions involving the loss of ICLCs and/or a reduction in its pacing potential and reactivity to cholecystokinin may promote CG pathogenesis. This review discusses the association between ICLCs and CG pathogenesis and provides a basis for further studies on the functions of ICLCs and the etiologies of CG. PMID:34046450 | PMC:PMC8130069 | DOI:10.12998/wjcc.v9.i15.3498 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.