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Αλέξανδρος Γ. Σφακιανάκης

Monday, November 16, 2020

Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2 production

alkiviadis.1961 shared this article with you from Inoreader

Nature Neuroscience, Published online: 16 November 2020; doi:10.1038/s41593-020-00735-y

Chun et al. find that a severe model of reactive astrocytes overproduces hydrogen peroxide, leading to the development of Alzheimer's disease-like pathologies, including neurodegeneration, tauopathy and memory impairment.
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