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Wednesday, October 28, 2020

Peroral Endoscopic Myotomy Is Effective for Patients With Achalasia and Normal Lower-Esophageal Sphincter Relaxation Pressures.

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Peroral Endoscopic Myotomy Is Effective for Patients With Achalasia and Normal Lower-Esophageal Sphincter Relaxation Pressures.

Clin Gastroenterol Hepatol. 2019 12;17(13):2803-2805

Authors: Sanaka MR, Parikh MP, Thota PN, Gupta NM, Gabbard S, Lopez R, Murthy S, Raja S

Abstract
Increased lower esophageal sphincter integrated relaxation pressure (LES-IRP) is a cardinal feature of achalasia. However, some patients with characteristic features of achalasia have normal LES-IRP.1,2 The efficacy of peroral endoscopic myotomy (POEM) in achalasia patients with normal LES-IRP is not well known. Hence, we aimed to compare POEM outcomes in achalasia patients with normal (<15 mm Hg) and increased (≥15 mm Hg) LES-IRP.

PMID: 30153516 [PubMed - indexed for MEDLINE]

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