Low expression of CIP4 in predicting worse overall survival: A potential biomarker for laryngeal cancer

xlomafota13 shared this article with you from Inoreader Low expression of CIP4 in predicting worse overall survival: A potential biomarker for laryngeal cancer Via Head and neck cancers by Lucheng Fang, Licai Shi, Wen Wang, Xiu Wu, Tingting Hu, Yideng Huang, Xingwang Rao Previous reports indicate that Cdc42-interacting protein-4 (CIP4) has previously been reported to plays an important role in the progression of various cancers. However, its correlation with laryngeal cancer (LC) remains unreported. Data from TCGA and GEO databases were used to evaluate the role of CIP4 in LC. Based on GEO and TCGA datasets, we analyzed the differences in CIP4 expression between normal and tumor samples. The Wilcoxon signed-rank test was used to analyze the relationship between clinical features and CIP4. Cox regression and the Kaplan-Meier analyses were used to identify the clinical characteristics associated with the overall survival. Also, the GEPIA database was used to confirm the relationship between CIP4 and overall survival. Lastly, Gene Set Enrichment Analysis (GSEA) was performed based on the TCGA dataset. CIP4 expression in LC was significantly associated with gender and tumor stage (p-values View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.