A novel therapy for granulomatous lobular mastitis: Local heat therapy

xlomafota13 shared this article with you from Inoreader A novel therapy for granulomatous lobular mastitis: Local heat therapy Via Experimental and therapeutic medicine Exp Ther Med. 2021 Oct;22(4):1156. doi: 10.3892/etm.2021.10590. Epub 2021 Aug 10. ABSTRACT Granulomatous lobular mastitis (GLM) is a chronic inflammatory breast condition that is characterized by granulomatous inflammation. GLM remains a refractory disease due to its failure to respond to routine anti-inflammatory therapies and its high recurrence rate. Thus, the present study aimed to investigate the application of local heat therapy in GLM as a potential therapeutic strategy. The results revealed that the application of local heat therapy was associated with a shortened remission time for GLM, while the remission and recurrence rates were similar to those of existing therapies. The median first remission time following local heat therapy was significantly decreased compared with that following corticosteroid therapy (5.30 months vs. 11.27 months; P<0.05). The remission rates were not significantly different between the local heat therapy (76.9%), extensive excision (90.4%) and the corticosteroid therapy (85.7%) groups (P>0.05). In addition, the recurrence rates were not statistically different between the groups (local heat therapy, 8.3%; extensive excision, 10%; and corticosteroid therapy, 10%; P>0.05). The local heat therapy showed mild adverse effects and shortened healing times compared to the other therapies; however, further confirmation is required. PMID:34504601 | PMC:PMC8393844 | DO I:10.3892/etm.2021.10590 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.