Processing hair follicles for transmission electron microscopy

xlomafota13 shared this article with you from Inoreader Processing hair follicles for transmission electron microscopy Via Experimental Dermatology Abstract Transmission electron microscopy (TEM) has greatly advanced our knowledge of hair growth and follicle morphogenesis, but complex preparations such as fixation, dehydration and embedding compromise ultrastructure. While recent developments with cryofixation have been shown to preserve the ultrastructure of biological materials close to native state, they do have limitations. This review will focus on each stage of the TEM sample preparation process and their effects on the structural integrity of follicles. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.