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Αλέξανδρος Γ. Σφακιανάκης

Monday, March 29, 2021

Primary central nervous system angiosarcoma with recurrent acute subdural hematoma

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Neurocirugia (Astur). 2021 Mar 22:S1130-1473(21)00027-0. doi: 10.1016/j.neucir.2021.02.002. Online ahead of print.

ABSTRACT

Angiosarcoma is an infrequent tumor among sarcomas, especially presenting as a primary tumor within the central nervous system, which can lead to a rapid neurological deterioration and death in few months. We present a 41-year old man with a right frontal enhancing hemorrhagic lesion. Surgery was performed with histopathological findings suggesting a primary central nervous system angiosarcoma. He was discharged uneventfully and received adjuvant chemotherapy and radiotherapy. At 5 months, the follow-up MRI showed two lesions with an acute subdural hematoma, suggesting a relapse. Surgery was again conducted finding tumoral membranes attached to the internal layer of the duramater around the right hemisphere. The patient died a few days later due to the recurrence of the subdural hematoma. This case report illustrates a r are and lethal complication of an unusual tumor. The literature reviewed shows that gross-total resection with adjuvant radiotherapy seems to be the best treatment of choice.

PMID:33766476 | DOI:10.1016/j.neucir.2021.02.002

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