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Αλέξανδρος Γ. Σφακιανάκης

Monday, February 1, 2021

Mohs Micrographic Surgery in Dermatofibrosarcoma Protuberans

xlomafota13 shared this article with you from Inoreader

Abstract

Characterization of patients, surgery procedures and the risk factors for Dermatofibrosarcoma Protuberans (DFSP) recurrences are poorly defined. In this study, we aimed to describe the demographics, tumor characteristics and interventions of DFSP treated with Micrographic Mohs Surgery (MSS) to determine the rate and risk factors for recurrence. Data were collected from REGESMOHS, a nationwide prospective cohort study of patients treated with MMS in Spain. From July 2013 to February 2020, 163 patients with DFSP that underwent MMS were included. DFSP were mostly located on trunk and extremities. Recurrent tumors had deeper tumor invasion and required higher number of MMS stages. Paraffin MMS was the most frequently used technique. Overall recurrence rate was 0.97 cases/100 person‐years (95% IC=0.36‐2.57). No differences were found in epidemiological, tumor, surgery characteristics or surgical technique (frozen or paraffin MMS (p=0.6641)) in terms of recurrence. Median follow‐u p time was 28.6 months with 414 patient‐years of follow‐up. In conclusion, we found an overall low recurrence rate of DFSP treated with MMS. None of the studied risk factors, including MMS techniques, was associated with higher risk for recurrence.

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