Impact of Colon Cancer Location on the Prognostic Significance of Nutritional Indexes and Inflammatory Markers

xlomafota13 shared this article with you from Inoreader Impact of Colon Cancer Location on the Prognostic Significance of Nutritional Indexes and Inflammatory Markers Via In vivo (Athens, Greece) In Vivo. 2021 Mar-Apr;35(2):1261-1269. doi: 10.21873/invivo.12377. ABSTRACT BACKGROUND/AIM: The prognosis of colorectal cancer is reported to differ depending on the tumor site, and clinical differences depending on the site of occurrence have gained attention. The aim was to compare nutrition index and inflammatory markers according to the site of colon cancer. PATIENTS AND METHODS: We retrospectively analyzed 272 cases of stage I-III colon cancer (55% males, 45% females). The clinical characteristics, nutrition index and inflammatory markers were compared between patients with right colon cancer (RCC, n=119) and those with left colon cancer (LCC, n=153), and the relapse-free survival was then compared. RESULTS: RCC was associated with older age (p=0.03), female gender (p=0.003), higher T stage (p=0.01), elevated platelet/lymphocyte ratio (PLR) (p=0.009), and elevated CONUT score (p=0.028). The prognostic values differed b etween RCC and LCC (RCC: CONUT score, p=0.04, LCC: PLR, p=0.02). CONCLUSION: RCC was associated with an elevated CONUT score and PLR. In RCC, the CONUT score was an independent recurrence factor, and in LCC, the PLR was an independent recurrence factor. PMID:33622929 | DOI:10.21873/invivo.12377 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.