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Tuesday, February 16, 2021

Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging.

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Active Giant Cell Vasculitis Diagnosis with 68Ga PSMA PET/CT Imaging.

Mol Imaging Radionucl Ther. 2021 Feb 09;30(1):57-59

Authors: Sağer MS, Bilgiç S, Uslu L, Asa S, Sağer G, Sönmezoğlu K

Abstract
Vasculitis is a multisystem disease characterized by inflammation with infiltration of leukocytes into the blood vessels. Giant cell arteritis (GCA) is the most common form of vasculitis that mostly affects medium- and large-sized arteries. 18Fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) is increasingly used to diagnose inflammation of large arteries in GCA. Galium-68 prostate-specific membrane antigen (PSMA) PET/CT has a vital role in the assessment of patients with prostate cancer for recurrence and metastasis of the disease. Various benign and non-prostate malignant conditions may give rise to increased PSMA uptake. Herein, we demonstrate that PSMA uptake can be seen in GCA.

PMID: 33586411 [PubMed]

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