Successful treatment of highly refractory Necrobiotic Xanthogranuloma with peginterferon alfa‐2a: a case report

xloma.fota13 shared this article with you from Inoreader Successful treatment of highly refractory Necrobiotic Xanthogranuloma with peginterferon alfa‐2a: a case report Via Clinical and Experimental Dermatology Abstract We present an update on a 63 year old gentleman with a six year history of necrobiotic xanthogranuloma (NXG) on a background of hepatitis C.1 Additional investigations revealed trace oligoclonal gammopathy with IgG kappa and lambda. To chronicle his treatment, he presented after unsuccessful treatment with nbUVB (burns), hydroxychloroquine (ineffective) and acitretin (life‐threatening side effects). In May 2014, there was mild subjective improvements with monthly 2g/kg intravenous immunoglobulin (IVIG) (over 5 days) for 4 months. In February 2015, 100mg of thalidomide daily for two months did not help. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.