Blog Archive

Αλέξανδρος Γ. Σφακιανάκης

Sunday, October 18, 2020

Medicine by Alexandros G. Sfakianakis

Improving aseptic injection standards in aesthetic clinical practice
Improving aseptic injection standards in aesthetic clinical practice: AbstractIntroductionThe rise in popularity and demand for non‐surgical injectable aesthetic procedures is inherently accompanied by an increase in reported complications, particularly those related to infection. Aseptic technique is under the control of aesthetic practitioners and can be modified to minimise the potential for cross‐contamination and infection. This should be a key consideration during all clinical procedures, particularly...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:43
Laser Tattoo Removal: Fundamental Principles and Practical Approach
Laser Tattoo Removal: Fundamental Principles and Practical Approach: ABSTRACTTattoos have long become a part of human civilization. However, as the number of people who get tattoos increases, so is the number of people who wish to have their tattoos removed. Compared to other methods, laser‐based devices are associated with the best efficacy and least side effects in tattoo removal. Lack of understanding of the fundamental principles of laser and managing its parameters may result in suboptimal result...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:37
Use of biologic therapies for psoriasis during pregnancy
Use of biologic therapies for psoriasis during pregnancy and long‐term outcomes of exposed children: A 14‐year real‐life experience at a tertiary center in Turkey and review of the literature: ABSTRACTData regarding the use of biologic therapies for psoriasis during pregnancy are scarce with even more limited knowledge about the long‐term safety of in utero exposure. We retrospectively evaluated nine pregnancies in six women with psoriasis who were exposed to biologic therapies between 2006 and 2019...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:37
Serum S100A12 levels: possible association with skin sclerosis and interstitial lung disease in systemic sclerosis
Serum S100A12 levels: possible association with skin sclerosis and interstitial lung disease in systemic sclerosis: AbstractDamage‐associated molecular patterns (DAMPs) have drawn much attention as a member of disease‐associated molecules in systemic sclerosis (SSc). In this study we investigated the potential contribution of S100A12, a member of DAMPs, to the development of SSc by evaluating S100A12 expression in the lesional skin and the clinical correlation of serum S100A12 levels. S100A12 expression...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:37
Early transcriptional changes after UVB treatment in atopic dermatitis includes inverse regulation of IL‐36γ and IL‐37
Early transcriptional changes after UVB treatment in atopic dermatitis includes inverse regulation of IL‐36γ and IL‐37: AbstractBackgroundPhototherapy with narrow‐band Ultraviolet B (nb‐UVB) is a major therapeutic option in atopic dermatitis (AD), yet knowledge of the early molecular responses to this treatment is lacking.ObjectiveTo map the early transcriptional changes in AD skin in response to nb‐UVB treatment.MethodsAdult patients (n = 16) with AD were included in the study and scored with validated...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:36
Effects of perioperative oral care on postoperative inflammation following heart valve surgery
Effects of perioperative oral care on postoperative inflammation following heart valve surgery: AbstractObjectiveWhether oral health care during the perioperative period can lead to a better outcome after heart valve surgery has not been adequately elucidated. We examined the effects of perioperative oral care on postoperative inflammation response in patients who underwent heart valve surgery.Materials and MethodsIn this retrospective cohort study, 223 patients scheduled for single valve heart surgery...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:36
Cerebrospinal Fluid Spread in a Child with Pleomorphic Xanthoastrocytoma
Cerebrospinal Fluid Spread in a Child with Pleomorphic Xanthoastrocytoma: A Report with Cytopathological Evidence: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Madhivanan Karthigeyan, Pankaj Kumar, Pravin Salunke, Manish Rohilla, Debjyoti Chatterjee, Chirag Kamal AhujaAbstractBackgroundPleomorphic xanthoastrocytoma (PXA), a relatively uncommon, World Health Organization grade II tumor of astrocytic origin, occurs in children and in general carries good prognosis....
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:35
Sellar Cholesterol Granuloma Mimicking Cystic Sellar Lesions
Sellar Cholesterol Granuloma Mimicking Cystic Sellar Lesions: A Report of Three Cases and Literature Review: Publication date: December 2020Source: World Neurosurgery, Volume 144Author(s): Martin Pilonieta, Monica Martin, Juan M. Revuelta Barbero, Douglas A. Hardesty, Ricardo L. Carrau, Bradley A. Otto, Jose Otero, Luma Ghalib, Daniel M. Prevedello
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:31
Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma
Validation of the UICC 8th edition staging of oral cavity squamous cell carcinoma in a UK cohort: The eighth edition of the Union for International Cancer Control (UICC) staging manual was recently introduced. The staging of oral cavity squamous cell carcinoma saw changes in relation to depth of invasion and extra-nodal extension. We aimed to evaluate this system and its prognostic ability in a UK cohort. A retrospective review was undertaken of patients diagnosed with squamous cell carcinoma (SCC)...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:30
Anatomy of the respiratory system in the, "Portrait of a Musician" by Leonardo da Vinci
Anatomy of the respiratory system in the, "Portrait of a Musician" by Leonardo da Vinci: The object of the research is the painting, Portrait of a Musician''. Upon closer examination of the painting, we discovered three details. Two have the shape of trachea and bronchi and the third a larynx. By moving the details through the program Paint X we got an image of the larynx, trachea and bronchi. The larynx is presented by thyroid and cricoid cartilage. The characteristic cartilaginous rings are distinguished...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:29
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats
A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening in rats: Methods for the non-invasive quantification of changes in bladder wall thickness as potential predictors of radiation cystitis in pre-clinical research would be desirable. The use of ultrasound for this aim se...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:28
Evaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatment
Evaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatment: Margins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Here, we proposed a margin concept that takes into co...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:28
The association between micronutrient status and sleep quality in patients with depression: a case-control study
The association between micronutrient status and sleep quality in patients with depression: a case-control study: AbstractPurposeFew previous studies estimated the association between micronutrient status and sleep quality; no previous work was done in patients with depression compared with healthy controls. MethodsUsing a case-control design, 96 patients with depression were age- and sex-matched with 96 healthy controls. Dietary assessment utilized a standardized questionnaire,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:27
Ipsilateral radiation for squamous cell carcinoma of the tonsil
Ipsilateral radiation for squamous cell carcinoma of the tonsil: American Radium Society appropriate use criteria executive summary: AbstractBackgroundWe conducted the current systemic review to provide up‐to‐date literature summary and optimal evidence‐based recommendations for ipsilateral radiation for squamous cell carcinoma of the tonsil.MethodsWe performed literature search of peer‐reviewed journals through PubMed. The search strategy and subject‐specific keywords were developed based on the...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:27
Leiomyosarcoma in a cervical myelomeningocele
Leiomyosarcoma in a cervical myelomeningocele: a rare complication in a neglected case: AbstractBackground and importanceAsymptomatic myelomeningoceles are usually more of cosmetic deformities and left without evaluation and untreated, amongst low socio-economic strata. Such midline swellings, if left neglected may become the seat for malignancies, usually of squamous cell origin. Clinical presentationThe authors report a case of an 18-year-old male patient who developed leiomyosarcoma...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:26
Recombinant human endostatin plus paclitaxel/nedaplatin for recurrent or metastatic advanced esophageal squamous cell carcinoma: a prospective, single-arm, open-label, phase II study
Recombinant human endostatin plus paclitaxel/nedaplatin for recurrent or metastatic advanced esophageal squamous cell carcinoma: a prospective, single-arm, open-label, phase II study: SummaryBackground The prognosis of esophageal squamous cell carcinoma (ESCC) are still poor. Nedaplatin/paclitaxel regimen has shown activity with lower toxicity in metastatic ESCC. Recombinant human endostatin (Rh-endostatin), an inhibitor of angiogenesis, has shown inhibitory effects on ESCC xenograft. We assessed...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:26
An ovarian torsion in a 2-year-old girl:
An ovarian torsion in a 2-year-old girl: a case report: Abdominal pain is one of the most common complaints by patients in the emergency department. Diarrhea, constipation, and urinary tract infection are the commonest etiologies among these patients, but there are...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:25
Perivascular epithelioid cell tumor (PEComa) of the kidney
Perivascular epithelioid cell tumor (PEComa) of the kidney: an overview of its management and outcomes: Journal of International Medical Research, Volume 48, Issue 10, October 2020. Perivascular epithelioid cell tumor (PEComa) is a rare mesenchymal tumor with unique histological and immunohistochemical characteristics. Malignant renal cell carcinoma is even rarer and its biological behavior is still not clear. We report here a case of malignant PEComa in a male patient. The first symptom of the patient...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:23
Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing with progression to neuromyelitis optica spectrum disorder
A rare case of short-lasting unilateral neuralgiform headache with conjunctival injection and tearing with progression to neuromyelitis optica spectrum disorder: Journal of International Medical Research, Volume 48, Issue 10, October 2020. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) is a rare primary headache syndrome. However, some cases of secondary SUNCT are attributed to underlying diseases such as demyelination. We herein report a case of SUNCT...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:22
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Brain SciencesBrain Sciences, Vol. 10, Pages 753: Understanding Novel Metaphors: A Milestone in the Developmental Trajectory of Children with Agenesis of the Corpus Callosum?Brain Sciences, Vol. 10, Pages 753: Understanding Novel Metaphors: A Milestone in the Developmental Trajectory of Children with Agenesis of the Corpus Callosum? Brain Sciences doi: 10.3390/brainsci10100753 Authors: Sergio Melogno Maria Antonietta Pinto Chiara Pollice Fausto Badolato Guido Trasimeni Pasquale Parisi This study...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:22
Oncogenic KRAS–expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice
Oncogenic KRAS–expressing organoids with biliary epithelial stem cell properties give rise to biliary tract cancer in mice: AbstractBiliary tract cancer (BTC) arises from biliary epithelial cells (BECs) and includes intrahepatic cholangiocarcinoma (IHCC), gallbladder cancer (GC), and extrahepatic cholangiocarcinoma (EHCC). Although frequent KRAS mutations and epigenetic changes at the INK4A/ARF locus have been identified, the molecular pathogenesis of BTC is unclear and the development of corresponding...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:16
Allergenicity at component level of subpollens particles from different sources obtained by osmolar shock: a molecular approach to thunderstorm‐related asthma outbreaks
Allergenicity at component level of subpollens particles from different sources obtained by osmolar shock: a molecular approach to thunderstorm‐related asthma outbreaks: AbstractBackgroundThe so‐called "thunderstorm asthma" (TA) is an uncommon but dramatic outbreak of asthma attacks occurring during a thunderstorm in the pollen and molds season. Mechanisms which make the pollen able to enter the deeper airways and provoke severe asthma symptoms are still unclear.ObjectiveTo test the hypothesis that...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:16
Advances and novel developments in mechanisms of allergic inflammation
Advances and novel developments in mechanisms of allergic inflammation: AbstractIn the past decade, research in the molecular and cellular underpinnings of basic and clinical immunology has significantly advanced our understanding of allergic disorders, allowing scientists and clinicians to diagnose and treat disorders such as asthma, allergic and nonallergic rhinitis, and food allergy. In this review, we discuss several significant recent developments in basic and clinical research as well as important...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:15
Functional properties of single motor units in the human medial pterygoid muscle: task relations and thresholds
Functional properties of single motor units in the human medial pterygoid muscle: task relations and thresholds: AbstractBackgroundLittle is known regarding the functional properties of single motor units (SMUs) in the medial pterygoid muscle (MPt) during jaw movements.ObjectivesThe aims are a) to report the thresholds of onset of MPt SMUs during 4 goal‐directed jaw movement tasks, and b) to determine whether the threshold of onset of SMU activation varies with the velocity of jaw movement and the...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:14
The prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population
The prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population: AbstractObjectivesThis study aimed to assess the prevalence of awake bruxism and sleep bruxism in the Dutch adolescent population. Materials and MethodsAs part of a large epidemiologic survey on oral health of the general Dutch adolescent population in 2017, a total of 920 subjects were asked about their bruxism behavior during daytime and during sleep. The collected data were subjected to stratified analysis by...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:14
Molecular Signature of Extracellular Matrix Pathology in Schizophrenia
Molecular Signature of Extracellular Matrix Pathology in Schizophrenia: AbstractGrowing evidence points to a critical involvement of the extracellular matrix (ECM) in the pathophysiology of schizophrenia (SZ). Decreases of perineuronal nets and altered expression of chondroitin sulphate proteoglycans in glial cells have been identified in several brain regions. GWAS data have identified several SZ vulnerability variants of genes encoding for ECM molecules. Given the potential relevance of ECM functions...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:14
Novel loss‐of‐function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice
Novel loss‐of‐function variants in DNAH17 cause multiple morphological abnormalities of the sperm flagella in humans and mice: AbstractMultiple morphological abnormalities of the flagella (MMAF) is a genetically heterogeneous disorder leading to male infertility. Recent studies have revealed that DNAH17 variants are associated with MAMF, yet there is no functional evidence in support of their pathnogenicity. Here, we recruited two consanguineous families of Pakistani and Chinese origins, respectively,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:13
"Double-Flash": An Innovative Method to Diagnose Papillary Thyroid Microcarcinomas
"Double-Flash": An Innovative Method to Diagnose Papillary Thyroid Microcarcinomas: Publication date: Available online 17 October 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Tiantong Zhu, Jingwen Shi, Bo Wang, Yue Yu, Ying Huang
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:12
Comparison of KD‐SR‐01 robotic partial nephrectomy and 3D‐laparoscopic partial nephrectomy from an operative and ergonomic perspective: a prospective randomized controlled study in porcine models
Comparison of KD‐SR‐01 robotic partial nephrectomy and 3D‐laparoscopic partial nephrectomy from an operative and ergonomic perspective: a prospective randomized controlled study in porcine models: AbstractBackgroundTo investigate the feasibility, validity and security of a new robot platform called KD‐SR‐01 and compare relative merits of KD‐SR‐01 robotic partial nephrectomy (KD‐RPN) and 3D‐Laparoscopic Partial Nephrectomy (3D‐LPN).MethodsTwelve porcine models were randomly and equally divided for...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:11
CTNNB1 p.L31P mutation in an ovarian endometrioid carcinoma with synchronous uterine endometrioid carcinoma
CTNNB1 p.L31P mutation in an ovarian endometrioid carcinoma with synchronous uterine endometrioid carcinoma: Publication date: Available online 18 October 2020Source: Pathology - Research and PracticeAuthor(s): Irene Pecorella, Anna Coppa, Arianna Nicolussi, Lucia Manganaro, Francesco Fiorentin, Innocenza Palaia, Ludovico MuziiAbstractWe performed next generation sequencing of DNA extracted from the neoplastic tissues obtained from a patient who underwent surgery for a large right ovarian carcinoma...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:10
High-risk factors for lymph node metastasis in contralateral central compartment in unilateral papillary thyroid carcinoma(cT1N0)
High-risk factors for lymph node metastasis in contralateral central compartment in unilateral papillary thyroid carcinoma(cT1N0): Publication date: Available online 18 October 2020Source: European Journal of Surgical OncologyAuthor(s): Bin Zhou, Jianwu QinAbstractObjectiveThe incidence of papillary thyroid carcinoma (PTC) increases yearly. Central lymph node metastasis (CLNM) is common in PTC. Many studies have addressed ipsilateral CLNM; however, few studies have evaluated contralateral CLNM. The...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:09
Hearing and Speech Processing in Midlife
Hearing and Speech Processing in Midlife: Publication date: Available online 17 October 2020Source: Hearing ResearchAuthor(s): Karen S. Helfer, Alexandra JesseHighlights•Changes to subjective and objective hearing are common among middle-aged adults.•Elevated pure-tone thresholds can explain only a portion of objective problems.•Audiovisual speech processing remains intact with aging.•Middle-aged adults exert more effort in speech understanding than younger adults.•Research on middle-aged adults...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:08
Microsurgical Treatment of a Complex Cognard V Tentorial Dural Fistula with Superior Cerebellar Artery Supply
Microsurgical Treatment of a Complex Cognard V Tentorial Dural Fistula with Superior Cerebellar Artery Supply: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Ryan Dimentberg, Svetlana Kvint, Peter Madsen, Gregory Glauser, Omar ChoudhriAbstractThis case video demonstrates a microsurgical technique for the clipping and obliteration of a Cognard V tentorial dural fistula. The patient was a 49-year-old male who presented with progressive upper and lower extremity...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:08
Hypothalamic Cavernomas: Pediatric
Hypothalamic Cavernomas: Pediatric Case Report with 8.5 Year Follow-up and Review of the Literature: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Gennadiy A. Katsevman, Bayan Razzaq, Cesar A. SerranoABSTRACTCavernous malformations (cavernomas) are angiographically occult vascular lesions that can present symptomatically or be discovered incidentally. Rarely, they present in the hypothalamus or in children. We describe the case of a 14-year-old male who presented...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:07
Comparative analysis of the Pipeline and the Derivo flowdiverters for the treatment of unruptured intracranial aneurysms – a multicentric study
Comparative analysis of the Pipeline and the Derivo flowdiverters for the treatment of unruptured intracranial aneurysms – a multicentric study: Publication date: Available online 17 October 2020Source: World NeurosurgeryAuthor(s): Charlotte Zaeske, Lukas Goertz, Franziska Dorn, Bernd Turowski, Nuran Abdullayev, Marc Schlamann, Thomas Liebig, Christoph Kabbasch
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:06
Multifaceted targeting of cationic liposomes via co-delivery of anti-IL-17 siRNA and corticosteroid for topical treatment of psoriasis
Multifaceted targeting of cationic liposomes via co-delivery of anti-IL-17 siRNA and corticosteroid for topical treatment of psoriasis: Publication date: December 2020Source: Medical Hypotheses, Volume 145Author(s): Krishna Yadav, Deependra Singh, Manju Rawat Singh, Madhulika Pradhan
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:05
WNT/β-catenin signaling in the development of liver cancers
WNT/β-catenin signaling in the development of liver cancers: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Shuai He, Shilei Tang
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:05
The role of glycogen synthase kinase 3 beta in multiple sclerosis
The role of glycogen synthase kinase 3 beta in multiple sclerosis: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Tayebeh Noori, Ahmad Reza Dehpour, Antoni Sureda, Sajad Fakhri, Eduardo Sobarzo-Sanchez, Mohammad Hosein Farzaei, Esra Küpeli Akkol, Zahra Khodarahmi, Seyede Zahra Hosseini, Seyede Darya Alavi, Samira Shirooie
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:04
Mild asymptomatic primary hyperparathyroidism ......Efficacy of parathyroidectomy compared with active surveillance
Efficacy of parathyroidectomy compared with active surveillance in patients with mild asymptomatic primary hyperparathyroidism: a systematic review and meta-analysis of randomized-controlled studies: AbstractObjectiveParathyroidectomy (PTx) has an established benefit in patients with symptomatic primary hyperparathyroidism (PHPT). However, its efficacy in mild asymptomatic PHPT has not been proven. This study aimed to systematically review and meta-analyze the best available evidence from randomized-controlled...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:03
SARS-CoV-2 Detection on Bronchoalveolar Lavage
SARS-CoV-2 Detection on Bronchoalveolar Lavage: An Italian Multicenter experience: Background: Bronchoscopy with bronchoalveolar lavage (BAL) during the SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) pandemic should be reserved to a limited number of clinical indications. The yield of BAL for the diagnosis of suspected or confirmed pulmonary SARS-CoV-2 infection is still unknown. Objectives: We aimed to evaluate the diagnostic ratio of BAL in detecting SARS-CoV-2 pulmonary infection...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:03
The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells
 Highlights•ENL has more prominent anti-leukemic effects than other flaxseeds lignans.•ENL promotes selective anti-proliferative and pro-apoptotic effects on AML cells.•The intrinsic apoptotic pathway is activated upon Enterolactone exposure.•This study offers new insights into the health benefits of flaxseeds.AbstractFlaxseeds have been known for their anti-cancerous effects due to the high abundance of lignans released upon ingestion. The most abundant lignan, secoisolariciresinol diglucoside (SDG),...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
09:00
A synergistic effect of Ambroxol and Beta-Glucosylceramide in alleviating immune-mediated hepatitis: A novel immunomodulatory non-immunosuppressive formulation for treatment of immune-mediated disorders
A synergistic effect of Ambroxol and Beta-Glucosylceramide in alleviating immune-mediated hepatitis: A novel immunomodulatory non-immunosuppressive formulation for treatment of immune-mediated disorders: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Tawfik Khoury, Yuval Ishay, Devorah Rotnemer-Golinkin, Lidya Zolotarovya, David Arkadir, Ari Zimran, Yaron IlanFigures (5)Biomedicine & PharmacotherapyVolume 132, December 2020, 110890A synergistic...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:58
Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13
Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13: Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Cristina Aguzzi, Oliviero Marinelli, Laura Zeppa, Giorgio Santoni, Filippo Maggi, Massimo NabissiFigures (10)Show all figuresExtras (2)Download allDocumentDocumentBiomedicine & PharmacotherapyVolume 132, December 2020, 110845Original articleEvaluation...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:56
Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy
Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy: Publication date: Available online 17 October 2020Source: Annals of Diagnostic PathologyAuthor(s): Pitra Tomas, Pivovarcikova Kristyna, Alaghehbandan Reza, Eva Maria Compérat, Hora Milan, Joanna Rogala, Maryna Slisarenko, Michal Michal, Hes OndrejFigures (4)Annals of Diagnostic PathologyAvailable online 17 October 2020, 151644In Press, Journal Pre-proofWhat are Journal...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:54
Association between carbonic anhydrase 9 expression and poor prognosis in sinonasal squamous cell carcinoma
Association between carbonic anhydrase 9 expression and poor prognosis in sinonasal squamous cell carcinoma: Publication date: Available online 17 October 2020Source: Annals of Diagnostic PathologyAuthor(s): Chunyan Hu, Huan Wang, Lan Lin, Xicai Sun, Dehui WangFigures (2)Tables (4)Table 1Table 2Table 3Table 4Annals of Diagnostic PathologyAvailable online 17 October 2020, 151643In Press, Journal Pre-proofWhat are Journal Pre-proof articles?Original ContributionAssociation between carbonic anhydrase...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:54
Structural remodeling of the lumbar multifidus, thoracolumbar fascia and lateral abdominal wall perimuscular connective tissues: A search for its potential determinants
Structural remodeling of the lumbar multifidus, thoracolumbar fascia and lateral abdominal wall perimuscular connective tissues: A search for its potential determinants: Determinants that influence remodeling of lumbar soft tissues need to be elucidated in order to understand the impact of different rehabilitation modalities. While age, sex and pain status explain some variability, modifiable factors such as physical activity level as well as trunk muscle thickness and function were involved. These...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:53
Ultrastructural evidence for telocytes in equine tendon
Ultrastructural evidence for telocytes in equine tendon: This study describes the characteristics of telocytes, located near blood vessels, in the equine tendon. Telocytes may represent an early step in the tendon‐derived stem cell differentiation process towards mature tenocytes "in vivo" based on a previous hypothesis that highlights telocytes as potential mesenchymal progenitor cells. Of particular interest is the presence of the primary cilium as a signalling antenna involved in tenocyte differentiation.AbstractThe...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:52
Blood oxygenation level dependent magnetic resonance imaging and diffusion weighted MRI imaging for benign and malignant breast cancer discrimination
Blood oxygenation level dependent magnetic resonance imaging and diffusion weighted MRI imaging for benign and malignant breast cancer discrimination: Publication date: Available online 17 October 2020Source: Magnetic Resonance ImagingAuthor(s): Roberta Fusco, Vincenza Granata, Paolo Pariante, Vincenzo Cerciello, Claudio Siani, Maurizio Di Bonito, Marika Valentino, Mario Sansone, Gerardo Botti, Antonella PetrilloAbstractPurposeThe purpose of this study is to assess Blood oxygenation level dependent...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:52
Scalp ripples can predict development of epilepsy
Scalp ripples can predict development of epilepsy after first unprovoked seizure in childhood: ObjectiveIdentification of children at risk of developing epilepsy after a first unprovoked seizure can be challenging. Interictal epileptiform discharges are associated with higher risk but have limited sensitivity and specificity. High frequency oscillations (HFOs) are newer biomarkers for epileptogenesis. We prospectively evaluated the predictive value of HFOs for developing epilepsy in scalp EEG of...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:50
Outcomes of Pre-Early Treatment for Retinopathy of Prematurity
Outcomes of Pre-Early Treatment for Retinopathy of Prematurity (Pre-ETROP): Authors Titawattanakul Y, Kulvichit K, Varadisai A, Mavichak AReceived 16 July 2020Accepted for publication 24 September 2020Published 16 October 2020 Volume 2020:14 Pages 3393—3397DOI https://doi.org/10.2147/OPTH.S268997Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2Editor who approved publication: Dr Scott FraserYothin Titawattanakul, Kittisak Kulvichit, Adisai Varadisai, Apivat...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:47
Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia: Authors Gallo FG, Plaitano C, Esposito Veneruso P, Magli AReceived 8 July 2020Accepted for publication 18 August 2020Published 19 October 2020 Volume 2020:14 Pages 3399—3402DOI https://doi.org/10.2147/OPTH.S266652Checked for plagiarism YesReview by Single anonymous peer reviewPeer reviewer comments 2Editor who approved publication: Dr Scott FraserFlavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli11Department...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:47
Selection for increased tibia length alters skull shape
Selection for increased tibia length in mice alters skull shape through parallel changes in developmental mechanisms [NEW RESULTS]: Bones in the vertebrate cranial base and limb skeleton grow by endochondral ossification, under the control of growth plates. Mechanisms of endochondral ossification are conserved across growth plates, which increases covariation in size and shape among bones, and in turn may lead to correlated changes in skeletal traits not under direct selection. We used micro-CT and...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:46
Phaeochromocytoma recurrence
Phaeochromocytoma recurrence in a patient with multiple endocrine neoplasia type 2A: AbstractMultiple endocrine neoplasia type 2A (MEN2A) is a hereditary syndrome associated with tumours of the endocrine system. Principally, it is characterized by medullary thyroid carcinoma (MTC) with some individuals also developing phaeochromocytoma and hyperparathyroidism. Patients with fewer than two clinical features require either an identification of a germline rearranged in transfection mutation, or MEN2A...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:44
Iatrogenically displaced third molar into the maxillary sinus
Presentation of an iatrogenically displaced third molar into the maxillary sinus in a 14-year-old patient successfully removed with an endoscopic approach: a case report and a review of the literature: AbstractOral surgeons remove third molars (wisdom teeth) to prevent impaction. Given the close anatomical relationship to the maxillary sinus, perforation and displacement of third molars into the maxillary sinus is a well-known phenomenon that is typically removed with a buccal mucoperiosteal flap...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:43
Unligated vertical vein presenting as a large atrio-portal shunt in adulthood
Unligated vertical vein presenting as a large atrio-portal shunt in adulthood: a case report: AbstractA 28-year-old male with infra-cardiac totally anomalous pulmonary venous connection (TAPVC) repaired as new-born presented in adulthood with right heart strain and very large left atrium to portal vein vessel. Residual connections from pulmonary veins to systemic circulation are believed to represent persistent 'vertical veins' (VV) not ligated at the time of the initial surgery. In our patient,...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:42
Upper limb phlegmasia cerulea dolens
Upper limb phlegmasia cerulea dolens treated with single-session suction thrombectomy: a case report: AbstractPhlegmasia cerulea dolens (PCD) of the lower limbs is a rare condition. PCD of the upper limbs is extremely uncommon, with only a select few cases documented in the literature. A complication of severe deep venous thrombosis, PCD, is characterized by the clinical triad of oedema, pain and limb cyanosis. Delays in treatment are associated with high rates of morbidity and mortality. We present...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:41
Long-term disease burden of intracranial meningioma
 Determinants and predictors for the long-term disease burden of intracranial meningioma patients03:00via    Neuro-OncologyAbstractIntroductionMeningioma is a heterogeneous disease and patients may suffer from long-term tumor- and treatment-related sequelae. To help identify patients at risk for these late effects, we first assessed variables associated with impaired long-term health-related quality of life (HRQoL) and impaired neurocognitive function on group level (i.e. determinants). Next, prediction...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:37
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  SAGE Publications: Journal of Investigative Medicine High Impact Case Reports: Table of ContentsBridging the Divisum: A Rare Case of Pancreaticopleural Fistula in the Setting of Complete Pancreatic Divisum Treated EndoscopicallyJournal of Investigative Medicine High Impact Case Reports, Volume 8, Issue , January-December 2020. A pancreaticopleural fistula (PPF) is a rare complication of chronic pancreatitis that occurs either due to a pancreatic duct disruption or a pseudocyst extension. A pancreatic...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:27
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Medical OncologyThe clinical significance of CD49e and CD56 for multiple myeloma in the novel agents eraAbstract Multiple myeloma (MM) is a hematological malignancy characterized by the proliferation of abnormal plasma cells in bone marrow. Flow cytometry distinguishes between normal and abnormal plasma cells by evaluating cluster of differentiation (CD) 56 and CD19 expression patterns. Moreover, immunophenotyping of mature plasma cell 1 (MPC-1) and very late antigen-5 (CD49e) identifies the maturity...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:26
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Radiation Oncology - Latest ArticlesEvaluation of OAR dose sparing and plan robustness of beam-specific PTV in lung cancer IMRT treatmentMargins are employed in radiotherapy treatment planning to mitigate the dosimetric effects of geometric uncertainties for the clinical target volume (CTV). Here, we proposed a margin concept that takes into co...Radiation Oncology - Latest ArticlesSat Oct 17, 2020 03:00A non-invasive ultrasound imaging method to measure acute radiation-induced bladder wall thickening...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:25
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Hearing ResearchHearing and Speech Processing in MidlifePublication date: Available online 17 October 2020Source: Hearing ResearchAuthor(s): Karen S. Helfer, Alexandra JesseHearing ResearchSun Oct 18, 2020 18:18"Translational Implications of the Interactions Between Hormones and Age-Related Hearing Loss"Publication date: Available online 15 October 2020Source: Hearing ResearchAuthor(s): R.D. Frisina, P. Bazard, M. Bauer, J. Pineros, X. Zhu, B. DingHearing ResearchFri Oct 16, 2020 17:48Cochlear...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:23
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  bioRxiv Subject Collection: Evolutionary BiologyIndividual variation in parental care drives divergence of sex roles [NEW RESULTS]In many animal species, parents provide care for their offspring, but the parental roles of the two sexes differ considerably between and within species. Here, we use an individual-based simulation approach to investigate the evolutionary emergence and stability of parental roles. Our conclusions are in striking contrast to the results of analytical models. In the absence...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:20
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  NutrientsNutrients, Vol. 12, Pages 3185: The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT StudyNutrients, Vol. 12, Pages 3185: The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study Nutrients doi: 10.3390/nu12103185 Authors: Michél Strauss-Kruger Ruan Kruger Wayne Smith Lebo F. Gafane-Matemane Gontse Mokwatsi Wen Wei Olga V. Fedorova Aletta E. Schutte...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:18
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Journal of Clinical MedicineJCM, Vol. 9, Pages 3332: The Eye as a Non-Invasive Window to the Microcirculation in Liver Cirrhosis: A Prospective Pilot StudyJCM, Vol. 9, Pages 3332: The Eye as a Non-Invasive Window to the Microcirculation in Liver Cirrhosis: A Prospective Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9103332 Authors: Fiona J Gifford Francesca Moroni Tariq E Farrah Kirstie Hetherington Tom J MacGillivray Peter C Hayes Neeraj Dhaun Jonathan A Fallowfield Microcirculatory...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:16
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  HealthcareHealthcare, Vol. 8, Pages 409: Suitability of Ultra-Short-Term Heart Rate Variability in Military TraineesHealthcare, Vol. 8, Pages 409: Suitability of Ultra-Short-Term Heart Rate Variability in Military Trainees Healthcare doi: 10.3390/healthcare8040409 Authors: Mubarak J. Alalyan Shaea A. Alkahtani Syed Shahid Habib Andrew A. Flatt We aimed to (a) evaluate the agreement between ultra-short-term and criterion resting heart rate variability (HRV) measures in military trainees, and (b)...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:14
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  AntibioticsAntibiotics, Vol. 9, Pages 713: Preoperative Antibiotic Prophylaxis in Elective Minor Surgical Procedures among Adults in Southern ItalyAntibiotics, Vol. 9, Pages 713: Preoperative Antibiotic Prophylaxis in Elective Minor Surgical Procedures among Adults in Southern Italy Antibiotics doi: 10.3390/antibiotics9100713 Authors: Giorgia Della Polla Aida Bianco Silvia Mazzea Francesco Napolitano Italo Francesco Angelillo Little is known regarding the factors associated with surgical antibiotic...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:12
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
  Frontiers in Oncology | New and Recent ArticlesSintilimab, a PD-1 Inhibitor, Completely Reversed Rarely Refractory Hypofibrinogenemia in a Gastric Cancer Patient: A Case Report and Review of the LiteratureWhile cancer is often related to hyperfibrinogenemia, it is rarely related to hypofibrinogenemia. Specifically, gastric cancer concomitant with unprovoked hypofibrinogenemia and the corresponding treatment approach have been rarely reported. We presented a case of gastric cancer in a 78-year-old...
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,
08:11
Nanomaterials, Vol. 10, Pages 2058: Perfluoropolyether Nanoemulsion Encapsulating Chlorin e6 for Sonodynamic and Photodynamic Therapy of Hypoxic Tumor
Nanomaterials, Vol. 10, Pages 2058: Perfluoropolyether Nanoemulsion Encapsulating Chlorin e6 for Sonodynamic and Photodynamic Therapy of Hypoxic Tumor Nanomaterials doi: 10.3390/nano10102058 Authors: Liang Hong Artem M. Pliss Ye Zhan Wenhan Zheng Jun Xia Liwei Liu Junle Qu Paras N. Prasad Sonodynamic therapy (SDT) has emerged as an important modality for cancer treatment. SDT utilizes ultrasound excitation, which overcomes the limitations of light penetration in...
Nanomaterials
03:00
Nanomaterials, Vol. 10, Pages 2059: Twin Domain Structure in Magnetically Doped Bi2Se3 Topological Insulator
Nanomaterials, Vol. 10, Pages 2059: Twin Domain Structure in Magnetically Doped Bi2Se3 Topological Insulator Nanomaterials doi: 10.3390/nano10102059 Authors: Jakub Šebesta Karel Carva Dominik Kriegner Jan Honolka Twin domains are naturally present in the topological insulator Bi2Se3 and strongly affect its properties. While studies of their behavior in an otherwise ideal Bi2Se3 structure exist, little is known about their possible interaction with other defects. Extra information...
Nanomaterials
03:00

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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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