RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription...
Wed Apr 22, 2020 10:05
Head and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.: Related ArticlesHead and neck squamous cell cancer associated with lymphoproliferative malignancies is aggressive.J Laryngol Otol. 2020 Apr 20;:1-3Authors: Li L, Hamilton L, Montgomery J, Stewart MAbstract BACKGROUND: Patients with non-Hodgkin's lymphoma and chronic lymphocytic leukaemia are at an elevated risk of further malignancy. Head and neck squamous cell carcinoma often presents with...
Wed Apr 22, 2020 09:54
Potential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.: Related ArticlesPotential of Pembrolizumab in Metastatic or Recurrent Head and Neck Cancer: Evidence to Date.Onco Targets Ther. 2020;13:3047-3059Authors: McCusker MG, Orkoulas-Razis D, Mehra RAbstract Relapsed and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a heterogeneous disease previously associated with poor prognosis and limited treatment options until the advent and...
Wed Apr 22, 2020 09:54
Chronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab - Diagnostic and Therapeutic Challenge: A Case Report.: Related ArticlesChronic and Severe Non-Lichenoid Oral Ulcers Induced by Nivolumab - Diagnostic and Therapeutic Challenge: A Case Report.Case Rep Oncol. 2020 Jan-Apr;13(1):314-320Authors: Cardona AF, Ruiz-Patiño A, Ricaurte L, Zatarain-Barrón ZL, Barrón F, Arrieta OAbstract Due to the widespread use of immune checkpoint inhibitors and the growing research efforts in this...
Wed Apr 22, 2020 09:54
The Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.: https://www.researchgate.net/publication/340673646_The_Carit_Maneuver_A_Novel_Approach_for_the_Relief_of_Shoulder_Dystocia-A_Case_Series/fulltext/5e99732d4585150839e3ba09/The-Carit-Maneuver-A-Novel-Approach-for-the-Relief-of-Shoulder-Dystocia-A-Case-Series.pdfRelated ArticlesThe Carit Maneuver: A Novel Approach for the Relief of Shoulder Dystocia-A Case Series.AJP Rep. 2020 Apr;10(2):e133-e138Authors: Gei AF,...
Wed Apr 22, 2020 09:53
Risk of head and neck cancer after chronic pancreatitis.: Related ArticlesRisk of head and neck cancer after chronic pancreatitis.Ann Transl Med. 2020 Mar;8(5):213Authors: Chen CH, Chen CH, Lin CL, Hsu CY, Kao CHAbstractBackground: To evaluate the relation of head and neck cancer to chronic pancreatitis by analyzing Taiwan's National Health Insurance Research Database.Methods: We identified 11,237 patients with chronic pancreatitis as the case cohort, which was propensity score matched with another...
Wed Apr 22, 2020 09:50
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems...
Wed Apr 22, 2020 09:42
Follicular Thyroid Neoplasms: Comparison of Clinicopathologic and Molecular Features of Atypical Adenomas and Follicular Thyroid Carcinomas: In follicular thyroid neoplasms without invasion, a diagnosis of atypical adenoma (AA) (follicular tumor of uncertain malignant potential) may be rendered if atypical features (indefinite capsular/vascular invasion, necrosis, solid growth, increased mitoses) are present. This study compares clinical, histologic, and molecular features of patients with AAs (n=31),...
Wed Apr 22, 2020 09:41
Primary Vascular Tumors of Bone: A Monoinstitutional Morphologic and Molecular Analysis of 427 Cases With Emphasis on Epithelioid Variants: Recent molecular discoveries have refined vascular bone tumor classification. To investigate the clinical relevance of these refinements, we reviewed all cases of primary vascular bone tumors treated at our Institute. On the basis of morphology, cases were assessed immunohistochemically and molecularly. A total of 427 cases of primary vascular tumor of bone with...
Wed Apr 22, 2020 09:41
Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions: As inflammatory myofibroblastic tumors (IMTs) have become more widely recognized in the female genital tract, an intriguing subset of uterine tumors associated with pregnancy has emerged. Whether uterine IMTs occurring in the setting of pregnancy are clinically or biologically distinct from other uterine IMTs is unknown. Furthermore, little is known...
Wed Apr 22, 2020 09:41
Primary Cutaneous CD4+ Small/Medium T-Cell Lymphoproliferative Disorders: A Clinical, Pathologic, and Molecular Study of 60 Cases Presenting With a Single Lesion: A Multicenter Study of the French Cutaneous Lymphoma Study Group: Primary cutaneous CD4+ small/medium T-cell lymphoproliferative disorder (PCSMLPD) is a recently recognized entity in the 2017 World Health Organization (WHO) classification. It belongs to the T-follicular helper (TFH) lymphoproliferations. The clinical, pathologic, and molecular...
Wed Apr 22, 2020 09:41
Prostatic Metaplasia of the Vagina and Uterine Cervix: An Androgen-associated Glandular Lesion of Surface Squamous Epithelium: Prostatic-type differentiation in the lower female genital tract is encountered rarely and its causes and clinical associations are not well established. Within the vagina, reports to date have invariably described ectopic prostatic-type differentiation as restricted to the lamina propria. We recently encountered a patient receiving testosterone for gender dysphoria whose...
Wed Apr 22, 2020 09:40
A Modified Histopathologic Staging in Penile Squamous Cell Carcinoma Predicts Nodal Metastasis and Outcome Better Than the Current AJCC Staging: Recently, the American Joint Committee on Cancer (AJCC) updated the staging system for penile squamous cell carcinoma. According to it, unlike its previous version, the involvement of urethra does not upstage the tumor; however, the involvement of corpora cavernosa (CC) does. The tumors involving CC are now staged pT3, whereas those involving corpora spongiosa...
Wed Apr 22, 2020 09:40
Gastrointestinal Malakoplakia: Clinicopathologic Analysis of 26 Cases: Malakoplakia is an inflammatory process related to defective macrophage response to bacterial infection. To further characterize the clinicopathologic manifestations of gastrointestinal malakoplakia, 26 cases were identified from 6 institutions. Hematoxylin and eosin-stained slides and available stains were reviewed, and pertinent clinicopathologic features analyzed. Sixteen patients were women (62%). Mean patient age was 64 (range:...
Wed Apr 22, 2020 09:40
Comparison of Systemic EBV-positive T-Cell and NK-Cell Lymphoproliferative Diseases of Childhood Based on Classification Evolution: New Classification, Old Problems: Systemic Epstein-Barr virus–positive T-cell and natural killer (NK)-cell lymphoproliferative diseases of childhood are a group of lethal diseases mostly affecting children and young adults. The Ohshima Grading System and the 2017 World Health Organization (WHO) classification have been used for classifying this spectrum, but these systems...
Wed Apr 22, 2020 09:39
Apocrine Variant of Pleomorphic Lobular Carcinoma In Situ: Further Clinical, Histopathologic, Immunohistochemical, and Molecular Characterization of an Emerging Entity: To date, the apocrine variant of lobular carcinoma in situ (AP-LCIS) has been cursorily described as a subtype of lobular carcinoma in situ (LCIS). We retrospectively reviewed 34 cases of AP-LCIS (including 23 associated with invasive lobular carcinoma) to fully characterize it. AP-LCIS typically presented with screen-detected calcifications...
Wed Apr 22, 2020 09:39
Skin-Colored Nodule on the Cutaneous Lip: Challenge:
Wed Apr 22, 2020 09:38
A Fatal Infection With Subtle and Nonspecific Signs and Symptoms in a Neonate: Challenge:
Wed Apr 22, 2020 09:36
Brownish and Indurated Plaques With Yellowish Papules: Challenge: No abstract available
Wed Apr 22, 2020 09:34
AUD : Last 20 articlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort StudyIntroduction: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations are essential to monitor the hearing health of noise-exposed workers. Objective: To compare the evolution of audiometric thresholds in the initial three evaluations at frequencies of 3, 4, and 6 kHz in groups of workers exposed or not to noise....
Wed Apr 22, 2020 09:33
pubmed: sleepInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature.Related ArticlesInvestigation and diagnostic imaging of suspected pulmonary embolism during pregnancy and the puerperium: A review of the literature. J Med Imaging Radiat Oncol. 2020 Apr 20;: Authors: Tester J, Hammerschlag G, Irving L, Pascoe D, Rees M Abstract Pulmonary embolism (PE) is a leading cause of maternal mortality with women at increased risk...
Wed Apr 22, 2020 09:32
AA pubmed: head and neckOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway.Related ArticlesOsteopromotive carbon dots promote bone regeneration through the PERK-eIF2α-ATF4 pathway. Biomater Sci. 2020 Apr 20;: Authors: Jin N, Jin N, Wang Z, Liu L, Meng L, Li D, Li X, Zhou D, Liu J, Bu W, Sun H, Yang B Abstract Bone defects are still an unsolved clinical issue that must be overcome. Carbon dots have shown very promising effects in biological therapy. In the current...
Wed Apr 22, 2020 09:31
pubmed: philosophy for medic...Long-term outcomes after childhood convulsive status epilepticus.Related ArticlesLong-term outcomes after childhood convulsive status epilepticus. Curr Opin Pediatr. 2019 12;31(6):763-768 Authors: Pujar S, Scott RC Abstract PURPOSE OF REVIEW: It is widely accepted that childhood convulsive status epilepticus (CSE) has associated short-term and long-term mortality and morbidity. However, the role of CSE itself on subsequent adverse outcomes is still debated. In addition,...
Wed Apr 22, 2020 09:29
ScienceDirect Publication: Cell ReportsBeta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal TransdifferentiationPublication date: 21 April 2020Source: Cell Reports, Volume 31, Issue 3Author(s): Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. BreaultScienceDirect Publication: Cell Reports18hProfiling of Small Ribosomal Subunits...
Wed Apr 22, 2020 09:27
edoc: No conditions. Results ordered -Date Deposited.The ABC taxonomy for medication adherence translated into French and GermanWe translated the ABC adherence taxonomy (i.e., seven terms and their corresponding definitions) published by Vrijens et al. (2012) into French (F) and German (G) without changing the original meaning with the aim to promote a standardised taxonomy for medication adherence to French- and German-speaking researchers and clinicians.; A Delphi survey was performed. To generate...
Wed Apr 22, 2020 09:26
Emergency Medicine Journal Online FirstPrognostic accuracy of the quick Sequential Organ Failure Assessment (qSOFA)-lactate criteria for mortality in adults with suspected bacterial infection in the emergency department of a hospital with limited resourcesBackgroundRoutine use of the Sequential Organ Failure Assessment (SOFA) score to prognosticate patients with sepsis is challenged by the requirement to perform numerous laboratory tests. The prognostic accuracy of the quick SOFA (qSOFA) without...
Wed Apr 22, 2020 09:25
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription...
Wed Apr 22, 2020 10:05
RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription...
Wed Apr 22, 2020 10:05
Cancer MedicineGatekeeping in cancer clinical trials in Canada: The ethics of recruiting the "ideal" patientThe judgments of healthcare professionals may negatively influence equitable access and recruitment to clinical cancer trials, especially for patient populations marginalized by factors such as geography, poverty, mental health/addiction, immigration status, and language. Systems‐level strategies are needed to address the barriers that constrain ethical recruitment to clinical trials. Abstract...
09:12
Association between polycystic ovary syndrome and the vaginal microbiome: a case‐control study: SummaryBackgroundPolycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. Some evidence suggests that dysbiosis of the gut microbiota could be associated with PCOS clinical parameters, but little is known for the association between vaginal microbiome and PCOS.ObjectiveTo determine differences in the vaginal microbiome between women with PCOS and healthy control...
09:11
Airborne transmission of severe acute respiratory syndrome coronavirus‐2 to healthcare workers: a narrative review: SummaryHealthcare workers are at risk of infection during the severe acute respiratory syndrome (SARS) coronavirus‐2 (SARS‐CoV‐2) pandemic. International guidance suggests direct droplet transmission is likely and airborne transmission occurs only with aerosol generating procedures. Recommendations determining infection control measures to ensure healthcare worker safety follow these...
09:11
AA pubmed: head and neckRedistributing of Working Schedules by the Infective Principle - Will The COVID-19 Pandemic Finally Make Us Remember the Names of People We Shake Hands With?Related ArticlesRedistributing of Working Schedules by the Infective Principle - Will The COVID-19 Pandemic Finally Make Us Remember the Names of People We Shake Hands With? Infect Control Hosp Epidemiol. 2020 Apr 21;:1-5 Authors: Marko Ć, Košec A, Petrana B PMID: 32312359 [PubMed - as supplied by publisher]AA pubmed:...
09:10
Indigenous Management of Parotid Sialocele Using Foley's Catheter: A Report of Two Cases: AbstractBackgroundParotid gland and duct injuries are rare complications following surgery of parotid gland and temporomandibular joint. Sialocele is a cavity filled with saliva, usually formed as a result of trauma to salivary gland/duct or an iatrogenic complication of surgery. Several methods of managing parotid duct injury have been reported in the literature. In this article, we describe an indigenous way...
09:07
Synovial Chondromatosis of the Temporomandibular Joint: AbstractSynovial chondromatosis is a rare condition characterized by the presence of loose cartilaginous bodies, due to the abnormal proliferation of synovial membrane. However, its manifestation in the temporomandibular joint is a rare finding, occurring predominantly in females. This case report describes the clinical features, diagnosis and management of a case of synovial chondromatosis.
09:07
Prediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm.: Related ArticlesPrediction mode of more than 5 central lymph nodes metastases in clinically node-negative ipsilateral papillary thyroid carcinoma with tumor size 1 to 4 cm.Medicine (Baltimore). 2020 Apr;99(16):e19809Authors: Jin L, Sun HL, Zhou L, Xie L, Zhuang YY, Wang JBAbstract According to the 2015 American Thyroid Association guidelines,...
09:06
Case report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.: Related ArticlesCase report of a cystic parathyroidal adenoma with rapid growth induced by cinacalcet.BMC Endocr Disord. 2020 Apr 20;20(1):53Authors: Werner C, Lupp A, Mtuka-Pardon G, Kloos C, Wolf G, Aschenbach R, Biermann A, Freesmeyer M, Seifert PAbstract BACKGROUND: Primary hyperparathyroidism is a rare condition of disease which can seldomly present as giant retrotrhyroideal cysts, complicating the...
09:05
AA pubmed: head and neckEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort Study.Related ArticlesEffect of Noise Exposure on 1,382 Metallurgical Workers in Periodic Audiometric Evaluation: A Cohort Study. Audiol Neurootol. 2020 Apr 21;:1-6 Authors: Silva VAR, Guimarães AC, Lavinsky J, Pauna HF, Castilho AM, Crespo AN Abstract INTRODUCTION: Noise-induced hearing loss is the most preventable cause of auditory impairment. Periodic audiometric evaluations...
09:05
CD44v3 protein-carrying tumor-derived exosomes in HNSCC patients' plasma as potential noninvasive biomarkers of disease activity.: Related ArticlesCD44v3 protein-carrying tumor-derived exosomes in HNSCC patients' plasma as potential noninvasive biomarkers of disease activity.Oncoimmunology. 2020;9(1):1747732Authors: Theodoraki MN, Matsumoto A, Beccard I, Hoffmann TK, Whiteside TLAbstract The molecular cargo of tumor-cell-derived exosomes (TEX) mimics that of parental tumor cells. Thus, TEX...
09:03
Squamous Cell and Adenoid Cystic Carcinoma Collision Tumor of the Soft Palate Treated with Surface Mold Brachytherapy.: Surface mold brachytherapy (SMB) is a well-established treatment for early stage head and neck cancers involving accessible sites. It has evolved from the radium era to low-dose rate and now to high-dose rate intensity-modulated interventional brachytherapy.Sep 9, 2019High-dose rate surface mold brachytherapy in a case of ...Related ArticlesSquamous Cell and Adenoid Cystic Carcinoma...
09:03
Cat-scratch Disease with Parinaud's Oculoglandular Syndrome.: Parinaud's oculoglandular syndrome is the combination of granulomatous conjunctivitis in one eye, and swollen lymph nodes in front of the ear on the same side. Most cases are caused by cat-scratch disease, although it is an unusual feature of this condition. Occasionally it may be caused by other infections.Parinaud's oculoglandular syndrome - WikipediaRelated ArticlesCat-scratch Disease with Parinaud's Oculoglandular Syndrome.Turk Arch...
09:02
Necrotizing Fasciitis due to Candida Infection after Thyroid Surgery.: Related ArticlesNecrotizing Fasciitis due to Candida Infection after Thyroid Surgery.Turk Arch Otorhinolaryngol. 2020 Mar;58(1):56-60Authors: Aslıer MAbstract Surgical site infections (SSIs) after thyroidectomy are very rare as it is a clean case surgery, even the patterns for the use of prophylactic antibiotics is disputable. Cutaneous and subcutaneous tissue infections are the most common type of SSIs that develop due...
09:01
Ewing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy.: Related ArticlesEwing Sarcoma of Larynx: A Rare Case in a 5-Year-Old Boy.Turk Arch Otorhinolaryngol. 2020 Mar;58(1):65-68Authors: Pasha HA, Ghaloo SK, Wasif M, Siddiqui MI, Din NUAbstract Ewing Sarcoma of the head and neck region is an extremely rare entity. Treatment usually involves surgery, chemotherapy and radiotherapy in varying sequences. We present the third case to date of Ewing sarcoma of the larynx in a paediatric population....
09:00
Eccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.: Eccrine porocarcinomas, are very rare malignant adnexal tumors arising from intra-epidermal ductal portion of eccrine sweat gland. More than 50% cases involve lower extremities (3). On rare occasion, it may involve head and neck region, upper limbs, trunk and abdomen (1, 3).Eccrine Porocarcinoma of Scalp: a Rare Case Report - NCBIRelated ArticlesEccrine porocarcinoma of the head and neck: Meta-analysis of 120 cases.Head Neck....
08:59
Incidence and survival trends of parotid malignancies over 42 years.: Related ArticlesIncidence and survival trends of parotid malignancies over 42 years.Head Neck. 2020 Apr 21;:Authors: Gupta A, Koochakzadeh S, Neskey DM, Nguyen SA, Lentsch EJAbstract BACKGROUND: There is a paucity of information regarding the incidence and survival of parotid malignancies over time. METHODS: The Surveillance, Epidemiology, and End Results population-based cancer registry was queried for parotid malignancies...
08:58
Latest headlines from BMJSeven days in medicine: 15-21 April 2020Covid-19Care home residents and staff are promised testsThe pledge to boost covid-19 testing for staff in UK care homes must be delivered promptly and be matched with greater transparency about the...Latest headlines from BMJnowMark above section as read pubmed: philosophy for medic...Comparing Quality of Life in Breast Cancer Patients Who Underwent Mastectomy Versus Breast-Conserving Surgery: A Meta-Analysis.Related ArticlesComparing...
08:57
Usefulness of intraoperative determination of central lymph node metastasis by palpation in papillary thyroid cancer.: Related ArticlesUsefulness of intraoperative determination of central lymph node metastasis by palpation in papillary thyroid cancer.Yeungnam Univ J Med. 2020 Apr 22;:Authors: Kim WW, Lee J, Jung JH, Park HY, Kim WH, Kim HJ, Park JY, Tufano RPAbstract Background: This study evaluated the usefulness of judgment of central lymph node (LN) metastasis by surgeon's palpation in...
08:56
pubmed: sleepEAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke.Related ArticlesEAN/ERS/ESO/ESRS statement on the impact of sleep disorders on risk and outcome of stroke. Eur J Neurol. 2020 Apr 20;: Authors: Bassetti CLA, Randerath W, Vignatelli L, Ferini-Strambi L, Brill AK, Bonsignore MR, Grote L, Jennum P, Leys D, Minnerup J, Nobili L, Tonia T, Morgan R, Kerry J, Riha R, McNicholas WT, Papavasileiou V Abstract BACKGROUND: Sleep disorders are highly prevalent...
08:54
Latest Results for Education and Information TechnologiesParents' beliefs about and associations to their elementary children's home technology usageAbstract This study sought to gather information through a survey of how newcomer parents' beliefs about technology usage and how they engage with technology as they support their children with twenty-first century literacies. Parent respondents (N = 70) were drawn from two publicly funded schools in the Niagara Region, Ontario, Canada, where the population...
08:54
The 24-inch gauge and the common gavel: an entered apprentice mason's perspective on the medical profession.: Related ArticlesThe 24-inch gauge and the common gavel: an entered apprentice mason's perspective on the medical profession.Proc (Bayl Univ Med Cent). 2020 Apr;33(2):298-301Authors: Kopel JAbstract By developing their character and philosophy, Freemasons have sought to improve their communities and society through the arts, sciences, humanities, and other fields and have made important...
08:53
Pediatric Patients with Previous Anaphylactic Reactions to General Anesthesia: a Review of Literature, Case Report, and Anesthetic Considerations: AbstractPurpose of ReviewIt is rare to see pediatric patients with previous perioperative anaphylaxis receiving future anesthesia, but it is critical to understand how to choose assessments, interpret the results, and develop a future anesthetic plan.Recent FindingsAnalysis of the results revealed that patients, at any age, regardless of sex and nationality,...
08:49
Targeting tumor-associated macrophages in head and neck squamous cell carcinoma.: Related ArticlesTargeting tumor-associated macrophages in head and neck squamous cell carcinoma.Oral Oncol. 2020 Apr 18;106:104723Authors: Li B, Ren M, Zhou X, Han Q, Cheng LAbstract In head and neck squamous cell carcinoma (HNSCC), tumor-associated macrophages (TAMs) are associated with a poorer prognosis. TAMs, derived from inflammatory monocyte, play a critical role in regulating tumor progression. Generally,...
08:49
Vitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.: Related ArticlesVitamin D Status as a Predictor of Postoperative Hypocalcemia after Thyroidectomy.Otolaryngol Head Neck Surg. 2020 Apr 21;:194599820917907Authors: Rubin SJ, Park JH, Pearce EN, Holick MF, McAneny D, Noordzij JPAbstract OBJECTIVE: To determine whether perioperative vitamin D levels are predictive of postoperative hypocalcemia in patients receiving thyroidectomy. STUDY DESIGN: Single center...
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Anesthesia for TORS for Oropharyngeal Carcinoma: Factors Associated with Prolonged Phase I Postanesthesia Recovery.: Related ArticlesAnesthesia for TORS for Oropharyngeal Carcinoma: Factors Associated with Prolonged Phase I Postanesthesia Recovery.Otolaryngol Head Neck Surg. 2020 Apr 21;:194599820915529Authors: Puccinelli CL, Moore EJ, Yin LX, Price DL, Janus JR, Weingarten TN, Van Abel KMAbstract OBJECTIVES: Clinical variables affecting anesthetic recovery following transoral robotic surgery...
08:48
BMJ Open Current IssueEffect of time interval from diagnosis to treatment for non-small cell lung cancer on survival: a national cohort study in TaiwanObjectivesThis study aimed to determine if treatment delay after non-small cell lung cancer (NSCLC) diagnosis impacts patient survival rate. Study designThis study is a natural experiment in Taiwan. A retrospective cohort investigation was conducted from 2004 to 2010, which included 42 962 patients with newly diagnosed NSCLC. MethodsWe identified...
08:47
Event-Related Potential Evidence of Enhanced Visual Processing in Auditory-Associated Cortex in Adults with Hearing Loss: Objective: The present study investigated the characteristics of visual processing in the auditory-associated cortex in adults with hearing loss using event-related potentials. Methods: Ten subjects with bilateral postlingual hearing loss were recruited. Ten age- and sex-matched normal-hearing subjects were included as controls. Visual ("sound" and "non-sound" photos)-evoked potentials...
08:46
Latest Results for European Journal on Criminal Policy and ResearchHousing Ex-Offenders in the Netherlands: Balancing Neighbourhood Safety and Human RightsAbstract The Universal Declaration of Human Rights recognises stable housing as a prerequisite for an adequate standard of living. A home provides shelter and enables personal development, thus contributing to the individual's well-being. Despite this, however, many struggle to find a place to live. In the Netherlands, people with a history of...
08:45
Evidence of Failure of Oral Third-Generation Cephalosporin Treatment for Shigella sonnei Infection: AbstractIn 2017, state health departments notified the Centers for Disease Control and Prevention about 4 patients with shigellosis who experienced persistent illness after treatment with oral third-generation cephalosporins. Given increasing antibiotic resistance among Shigella, these cases highlight the need to evaluate the efficacy of oral cephalosporins for shigellosis.The disease is caused by Shigella bacteria,...
08:41
Moderate to severe hyperphosphataemia as an independent prognostic factor for 28-day mortality in adult patients with sepsis: BackgroundIschaemic tissue injury caused by tissue hypoperfusion is one of the major consequences of sepsis. Phosphate concentrations are elevated in ischaemic tissue injury. This study was performed to investigate the association of phosphate concentrations with mortality in patients with sepsis.MethodsThis was a retrospective cohort study of patients with sepsis conducted...
08:40
Morphological study of the rabbit gustatory lingual papillae during postnatal life by light and scanning electron microscopy: AbstractThis study aimed to investigate the postnatal morphological features of rabbit's lingual gustatory papillae using histological, histochemical, morphometrical and scanning electron microscopical studies. A total of 48 New Zealand rabbits (1, 7, 15, 23, 30, 60 days postnatal) were used as the material. Tongue consisted of an apex, body and root with three types of gustatory...
08:40
Advances and perspectives of dendritic cell-based active immunotherapies in follicular lymphoma: AbstractFollicular lymphoma (FL) is a remarkably immune-responsive malignancy, which is still considered incurable. As, standard immunochemotherapy is complex, toxic and not curative, improvement in FL care is now a crucial topic in hemato-oncology. Recently, we and others have shown that dendritic cell (DC)-based therapies allow a specific immune response associated with sustained lymphoma regression...
08:39
Massive pulmonary embolism in pregnancy: intra-arrest thrombolysis and resuscitative hysterotomy: Massive pulmonary embolism (PE) is a leading cause of maternal death and may require intra-arrest thrombolysis as well as resuscitative hysterotomy. The case presented is a primigravida in her mid-30s at 28 weeks gestation. The patient presented to the emergency department after out-of-hospital cardiac arrest. Return of spontaneous circulation (ROSC) was achieved but not sustained. Episodic cardiopulmonary...
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Supraclavicular left neck mass: an unusual presentation of metastatic testicular cancer in two older men: Two male patients, aged 55 and 75 years, were referred to the ENT and haematology team respectively, with an asymptomatic left supraclavicular neck mass. Investigations revealed metastatic primary testicular seminoma. CT contrast study of the thorax, abdomen and pelvis demonstrated an additional left para-aortic nodal mass in both cases. The initial presentation of a solitary left neck lump from...
08:37
Malignant peripheral nerve sheath tumour of thyroid: a diagnostic dilemma: Malignant peripheral nerve sheath tumours of thyroid are rare entities that can present a diagnostic dilemma. We present the case of a patient who presented with neck mass with a history of multiple neck surgeries and airway compression. The patient's previous histopathology was mistaken for Riedel's thyroiditis in an outside hospital, which delayed appropriate treatment leading to suffering on part of the patient and frustration...
08:36
BMJ Case Reports Last 6 IssuesFollicular dendritic cell sarcoma and its response to immune checkpoint inhibitors nivolumab and ipilimumabFollicular dendritic cell sarcoma (FDCS) is a rare and unusual cancer that arises from sustentacular cells of the lymph node that present antigen to B cells, rather than lymphocytes themselves. While surgery for primary disease is still paramount in primary management, for unresectable, recurrent and metastatic tumours, FDCS is frequently treated with anthracycline-based...
08:36
Bilateral Fan-Shaped Septal Extension Struts in East Asian Augmentation Rhinoplasty: AbstractBackgroundFor costal cartilage-based rhinoplasty, a method that could properly manage warping of the columellar strut graft and facilitate establishing a stable cartilaginous framework remains desirable. In this study, the authors present a new graft design named bilateral septal extension strut. It utilizes a pair of cartilage grafts with the shape of a fan, which are bilaterally fixated to the septum. Such...
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Latest Results for AGEMitochondrial adaptations in liver and skeletal muscle to pro-longevity nutritional and genetic interventions: the crosstalk between calorie restriction and CYB5R3 overexpression in transgenic miceAbstract Calorie restriction without malnutrition (CR) is considered as the most effective nongenetic nor pharmacological intervention that promotes healthy aging phenotypes and can extend lifespan in most model organisms. Lifelong CR leads to an increase of cytochrome b5 reductase-3...
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RSC - Photochem. Photobiol. Sci. latest articlesEffect of ultraviolet radiation on vertebrate animals: update from ethological and medical perspectivesPhotochem. Photobiol. Sci., 2020, Advance ArticleDOI: 10.1039/C9PP00488B, PerspectiveClaire Vergneau-Grosset, Franck PéronMany animals under human care are kept indoors to prevent infectious diseases, to facilitate environment control, or due to the lifestyle of their owners. This article will review published information about ultraviolet effects...
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Correlation of p53 expression with Clinical Presentation and Prognosis of Oral Squamous Cell Carcinoma Patients: A Pilot Study: AbstractMutations of p53 gene is one of the most common events in human cancers including oral squamous cell carcinoma (OSCC). However, its role in carcinogenesis and association with regard to prognosis is still under investigation and unclear. The aim was to study the expression of p53 in patients of OSCC and correlation with clinical presentation and prognosis. In this...
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Palatopharyngoplasty and Palatal Anatomy and Phenotypes for Treatment of Sleep Apnea in the Twenty-first Century: Successful palatopharyngoplasty is critical for successful sleep apnea surgery. Traditional uvulopalatopharyngoplasty was primarily excisional, whereas newer techniques, such as expansion sphincterpharyngoplasty, are more reconstructive. Studies of flow dynamics even demonstrate that the effectiveness of maxillofacial surgery is significantly mediated through stiffening and enlargement...
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Implantable Neurostimulation for Treatment of Sleep Apnea: Hypoglossal nerve stimulation (HNS) therapy represents a novel approach and a paradigm shift in the evolution of obstructive sleep apnea (OSA) treatment as a hybrid surgically implanted, medically titratable device. Unlike traditional sleep apnea surgical procedures, HNS augments the neuromuscular activity of the pharynx, preserves upper airway structure and function, and has the potential to provide multilevel upper airway improvement with...
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Journal of Dairy ScienceEstimating degradation of individual essential amino acids in fish meal and blood meal by rumen microbes in a dual-flow continuous-culture systemPublication date: Available online 22 April 2020Source: Journal of Dairy ScienceAuthor(s): S. Gargallo, A. Ferret, S. CalsamigliaJournal of Dairy Science6h<em>Symposium review:</em> Development, implementation, and perspectives of health evaluations in the United States<a name="bfn1" href="#fn1" aria-label="open footnote"...
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Sonographic exploration for fascial exploration (SEFE) in necrotizing fasciitis: a case report: AbstractBackgroundNecrotizing skin and soft tissue infections are life-threatening conditions. Reliance on gas in tissue planes leads to worsened outcomes in patients with non-gas forming types of necrotizing fasciitis (NF).Case presentationWe present a case of Group A Strep (GAS) necrotizing fasciitis, which was identified at bedside with point-of-care ultrasound (US) including an area of subfascial fluid....
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edoc: No conditions. Results ordered -Date Deposited.Connecting single conductive polymers to a single functional moleculeWe have developed a method using a scanning tunneling microscope (STM) probe tip to control the chain polymerization of diacetylene compounds in a self-ordered layer, thereby creating conjugated polydiacetylene nanowires. When a small amount of phthalocyanine was deposited on a molecular layer of diacetylene compound, we found adsorbed and stabilized phthalocyanine single molecules....
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edoc: No conditions. Results ordered -Date Deposited.Standardized protocols and procedures can precisely and accurately quantify non-structural carbohydratesNon-structural carbohydrates (NSCs), the stored products of photosynthesis, building blocks for growth and fuel for respiration, are central to plant metabolism, but their measurement is challenging. Differences in methods and procedures among laboratories can cause results to vary widely, limiting our ability to integrate and generalize patterns...
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Latest headlines from BMJHelen Salisbury: Who is vulnerable?The Easter bank holidays were cancelled for general practices at short notice, to take the pressure off out-of-hours services in anticipation of a rise in demand. Most of my patients assumed that we...Latest headlines from BMJ18hMatt Morgan: Hold onto your red threadMy Welsh comprehensive school education stood me in good stead for rugby, but less so for Greek mythology. I may have come late to the classics, but I have recently read about...
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An impact of microscopic positive margin on incomplete response after I-131 treatment in differentiated thyroid cancer: AbstractObjectiveTo find an impact of microscopic positive margin on incomplete response after initial I-131 therapy in differentiated thyroid cancer.MethodsWe retrospectively recruited patients with differentiated thyroid cancer who underwent total thyroidectomy and received the first dose of radioiodine during January 2014–February 2018. Patients with grossly incomplete tumor...
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Hindawi Publishing CorporationEnergy Dissipation Characteristic of Red Sandstone in the Dynamic Brazilian Disc Test with SHPB SetupIn order to quantitatively investigate the energy dissipation characteristic during the dynamic tension failure of rock materials, the dynamic Brazilian disc tests on red sandstone were conducted using the split Hopkinson pressure bar (SHPB) setup. The states of the specimens after different incident energies can be divided into three forms (i.e., the unruptured state,...
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Remove ads Hindawi Publishing CorporationEffect of Huangqin Tang on Urine Metabolic Profile in Rats with Ulcerative Colitis Based on UPLC-Q-Exactive Orbitrap MSAs a classic prescription, Huangqin Tang (HQT) has been widely applied to treat ulcerative colitis (UC), although its pharmacological mechanisms are not clear. In this study, urine metabolomics was first analysed to explore the therapeutic mechanisms of HQT in UC rats induced by TNBS. We identified 28 potential biomarkers affected by HQT that...
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The Postoperative Lymphocyte to Monocyte Ratio Change Predicts Poor Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma Undergoing Curative Resection: Background. Postoperative lymphocyte to monocyte ratio (post-LMR) change (LMRc) reflects the dynamic change of balance between inflammatory reaction and immune reaction after curative operation. An elevated preoperative LMR (pre-LMR) has been shown to be a prognostic factor in patients with esophageal squamous cell carcinoma (ESCC),...
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JBC Papers in Press{alpha}2, 3-linkage of sialic acid to a GPI-anchor and an unpredicted GPI attachment site in human prion protein [Glycobiology and Extracellular Matrices]Prion diseases are transmissible, lethal neurodegenerative disorders caused by accumulation of the aggregated scrapie form of prion protein (PrPSc) after conversion of cellular prion protein (PrPC). The glycosylphosphatidylinositol (GPI) anchor of PrPC is involved in prion disease pathogenesis, and especially sialic acid in a...
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Giant Thrombosis at Left Anterior Descending Artery Aneurysm in a 10-Year Old Boy with Granulomatosis with Polyangiitis: Granulomatosis with polyangiitis (GPA), necrotizing vasculitis of small and medium-sized vessels, is traditionally believed to mainly affect respiratory tract with additional focal kidney involvements as its primary manifestations with a relatively rare annual incidence rate of 20-50 cases per million. Six percent of the affected cases have cardiac involvements; among which, aneurysms...
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MCP Papers in PressRobust summarization and inference in proteome-wide label-free quantification [Research]Label-Free Quantitative mass spectrometry based workflows for differential expression (DE) analysis of proteins impose important challenges on the data analysis due to peptide-specific effects and context dependent missingness of peptide intensities. Peptide-based workflows, like MSqRob, test for DE directly from peptide intensities and outperform summarization methods which first aggregate...
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RCNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All!Related ArticlesNull Cell Adenoma of the Pituitary: Pseudo-rosettes Say It Best When Immunohistochemistry Says Nothing At All! Head Neck Pathol. 2019 Dec;13(4):677-680 Authors: Singh V, Gupta K, Salunke P, Dhandapani SS Abstract Null cell adenoma is composed of adenohypophyseal cells that show no evidence of any specific cell type differentiation by immunohistochemistry or transcription...
Wed Apr 22, 2020 10:05
VirusesViruses, Vol. 12, Pages 474: Determination of Protein Interactions among Replication Components of Apple Necrotic Mosaic VirusViruses, Vol. 12, Pages 474: Determination of Protein Interactions among Replication Components of Apple Necrotic Mosaic Virus Viruses doi: 10.3390/v12040474 Authors: Zhen-Lu Zhang Fu-Jun Zhang Peng-Fei Zheng Yin-Huan Xie Chun-Xiang You Yu-Jin Hao Apple mosaic disease is one of the most widely distributed and destructive diseases in apple cultivation worldwide, especially...
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NutrientsNutrients, Vol. 12, Pages 1171: Normal-Weight Obesity Is Associated with Poorer Cardiometabolic Profile and Lower Physical Fitness Levels in Children and AdolescentsNutrients, Vol. 12, Pages 1171: Normal-Weight Obesity Is Associated with Poorer Cardiometabolic Profile and Lower Physical Fitness Levels in Children and Adolescents Nutrients doi: 10.3390/nu12041171 Authors: Antonio García-Hermoso Cesar Agostinis-Sobrinho Gloria Eugenia Camargo-Villalba Nubia Mercedes González-Jiménez Mikel...
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MedicinaMedicina, Vol. 56, Pages 192: The Role of VEGFA, COX2, HUR and CUGBP2 in Predicting the Response to Neoadjuvant Therapy in Rectal Cancer PatientsMedicina, Vol. 56, Pages 192: The Role of VEGFA, COX2, HUR and CUGBP2 in Predicting the Response to Neoadjuvant Therapy in Rectal Cancer Patients Medicina doi: 10.3390/medicina56040192 Authors: Pauzas Gyvyte Latkauskas Kairevice Lizdenis Svagzdys Birgiolaite Kuliaviene Kupcinskas Tamelis Background and objectives: The effectiveness of neoadjuvant...
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International Journal of Molecular SciencesIJMS, Vol. 21, Pages 2936: Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial TissueIJMS, Vol. 21, Pages 2936: Sensitivity of the Fasciae to the Endocannabinoid System: Production of Hyaluronan-Rich Vesicles and Potential Peripheral Effects of Cannabinoids in Fascial Tissue International Journal of Molecular Sciences doi: 10.3390/ijms21082936 Authors:...
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International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 2894: Evidence Supports PA Prescription for Parkinson's Disease: Motor Symptoms and Non-Motor Features: A Scoping ReviewIJERPH, Vol. 17, Pages 2894: Evidence Supports PA Prescription for Parkinson's Disease: Motor Symptoms and Non-Motor Features: A Scoping Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17082894 Authors: Yi-Chen Cheng Chun-Hsien Su Parkinson's disease...
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CellsCells, Vol. 9, Pages 1048: VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring After Maternal Immune ActivationCells, Vol. 9, Pages 1048: VEGF Treatment Ameliorates Depression-Like Behavior in Adult Offspring After Maternal Immune Activation Cells doi: 10.3390/cells9041048 Authors: Spyridon Sideromenos Claudia Lindtner Alice Zambon Orsolya Horvath Angelika Berger Daniela D. Pollak Maternal immune activation (MIA) during pregnancy impacts offspring neurodevelopmental trajectories...
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AntibioticsAntibiotics, Vol. 9, Pages 200: Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumanniiAntibiotics, Vol. 9, Pages 200: Investigating Bacteriophages Targeting the Opportunistic Pathogen Acinetobacter baumannii Antibiotics doi: 10.3390/antibiotics9040200 Authors: Kathryn M. Styles Rapee Thummeepak Udomluk Leungtongkam Sophie E. Smith Gabrielle S. Christie Andrew Millard John Moat Christopher G. Dowson Elizabeth M. H. Wellington Sutthirat Sitthisak Antonia...
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Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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