Blog Archive

Αλέξανδρος Γ. Σφακιανάκης

Wednesday, April 10, 2019

Medicine


The extracellular matrix in tumor progression and metastasis
Abstract The extracellular matrix (ECM) constitutes the scaffold of tissues and organs. It is a complex network of extracellular proteins, proteoglycans and glycoproteins, which form supramolecular aggregates, such as fibrils and sheet-like networks. In addition to its biochemical composition, including the covalent intermolecular cross-linkages, the ECM is also characterized by its biophysical parameters, such as topography, molecular density, stiffness/rigidity and tension. Taking...
Latest Results
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Effects of resveratrol and its analogue pterostilbene, on NOV/CCN3 adipokine in adipose tissue from rats fed a high-fat high-sucrose diet
Abstract Nephroblastoma overexpressed protein, also called NOV/CCN3, is an adipokine which is present in various tissues and recently linked to obesity. The objective of the study was to determine the effect of resveratrol and pterostilbene on NOV/CCN3 in adipose tissue from rats fed an obesogenic diet. Thirty-six male Wistar rats were split into four groups (n = 9): fed a standard diet (CC), high-fat high-sucrose (HFS) diet supplemented with resveratrol (RSV; 30 mg/kg/day) or...
Latest Results for Journal of Physiology and Biochemistry
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The popular model annelid Enchytraeus albidus is only one species in a complex of seashore white worms (Clitellata, Enchytraeidae)
Abstract The white worm Enchytraeus albidus Henle, 1837 (Clitellata, Enchytraeidae) is easy to keep in laboratory cultures, and has therefore been employed as a model organism in basic and applied biological research. Its natural habitat includes terrestrial composts and wrack beds on seashores. However, the name E. albidus is currently used for a complex of morphologically similar and closely related species. We here revise the components of the E. albidus species complex based...
Latest Results for Organisms Diversity
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Development of New Antithrombotic Regimens for Patients with Acute Coronary Syndrome
Abstract Patients with acute coronary syndrome (ACS) require long-term antithrombotic intervention to reduce the risk of further ischemic events; dual antiplatelet therapy with a P2Y12 inhibitor and acetylsalicylic acid (ASA) is the current standard of care. However, pivotal clinical trials report that patients receiving this treatment have a residual risk of approximately 10% for further ischemic events. The development of non-vitamin K antagonist oral anticoagulants (NOACs) has...
Latest Results for Clinical Drug Investigation
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Primary central nervous system post-transplant lymphoproliferative disorders: the spectrum of imaging appearances and differential
Abstract Objective Central nervous system post-transplant lymphoproliferative disorder (CNS-PTLD) is a rare disease that presents with non-specific signs and symptoms. The purpose of this article is to present the imaging appearances of CNS-PTLD by magnetic resonance imaging. We highlight the differential diagnostic considerations including primary central nervous system lymphoma, glioblastoma, cerebral abscess, and metastatic disease....
Latest Results
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Superpixel based land cover classification of VHR satellite image combining multi-scale CNN and scale parameter estimation
Abstract Traditional classification methods, which use low-level features, have failed to gain satisfactory classification results of very high spatial resolution (VHR) remote sensing images. Even though per-pixel classification method based on convolutional neural network (CNN) (Per-pixel CNN) achieved higher accuracy with the help of high-level features, this method still has limitations. Per-superpixel classification method based on CNN (Per-superpixel CNN) overcomes the limitations...
Latest Results for Earth Science Informatics
Wed Apr 10, 2019 03:00
Wood Biomass and Carbon Pools within a Floodplain Forest of the Congaree River, South Carolina, USA
Abstract Riverine forests support high rates of plant productivity, yet total wood carbon (C) stocks in these systems remain understudied. We measured C concentrations and dry mass of live and dead detrital wood to understand their importance relative to total ecosystem C storage across an elevation gradient on the floodplain of the Congaree River. Our study sites included a low elevation bald cypress swamp and three higher elevation mature mixed bottomland hardwood communities....
Latest Results for Wetlands
Wed Apr 10, 2019 03:00
Landscape-Level Consequences of Rising Sea-Level on Coastal Wetlands: Saltwater Intrusion Drives Displacement and Mortality in the Twenty-First Century
Abstract Coastal wetlands are shrinking rapidly due to land-use activities. Accelerated sea-level rise (SLR) associated to the warming climate is also affecting coastal wetlands, particularly in islands with limited coastal plains. We analyzed coastal wetland changes in Puerto Rico by applying the Sea Level Affecting Marshes Model under two scenarios by 2100. We also analyzed mortality and recruitment in a freshwater swamp dominated by the tree Pterocarpus officinalis Jacq. in...
Latest Results for Wetlands
Wed Apr 10, 2019 03:00
Carbon Dioxide Concentrations and Efflux from Permanent, Semi-Permanent, and Temporary Subalpine Ponds
Abstract Small ponds account for a disproportionately high percentage of carbon dioxide emissions relative to their small surface area. It is therefore crucial to understand carbon flow in these ponds to refine the current global carbon budget, especially because climate change is affecting pond hydrology. High elevation ponds in the Elk Mountains of western Colorado are drying more frequently as the timing of snowmelt advances. We compared CO2 concentrations and fluxes among ponds...
Latest Results for Wetlands
Wed Apr 10, 2019 03:00
Investigating the effects of the flipped classroom model on Omani EFL learners' motivation level in English speaking performance
Abstract In Oman, a noteworthy move has been made towards student-centered instructional design especially in higher education facilitated by emerging technology. The current study aims to examine the effect of implementing the Flipped Classroom Model (FCM) on the motivation level of Omani EFL (English as a Foreign Language) learners to speak English. A mixed methods approach was used in this quasi experimental study. In the quantitative dimension, a Motivation in English Speaking...
Latest Results for Education and Information Technologies
Wed Apr 10, 2019 03:00
Integrated lipid production, CO 2 fixation, and removal of SO 2 and NO from simulated flue gas by oleaginous Chlorella pyrenoidosa
Abstract CO2, SO2, and NO are the main components of flue gas and can cause serious environmental issues. Utilization of these compounds in oleaginous microalgae cultivation not only could reduce air pollution but could also produce feedstock for biodiesel production. However, the continuous input of SO2 and NO inhibits microalgal growth. In this study, the toxicity of simulated flue gas (15% CO2, 0.03% SO2, and 0.03% NO, balanced with N2) was reduced through automatic pH feedback...
Latest Results
Wed Apr 10, 2019 03:00
Ecological risk assessment of metals in sediments and selective plants of Uchalli Wetland Complex (UWC)—a Ramsar site
Abstract Wetlands act as kidneys of land and facilitate remediation of metals and other harmful pollutants through uptake by aquatic macrophytes. The aim of the present study was to investigate metal concentrations in sediments and plants, sources of metal origin, and contamination level in Uchalli Wetland Complex. Sediment samples were collected from 15 randomly selected sites. Metal concentrations (Cd, Pb, Ni, Cu, Zn, Cr, As, Mn) in sediments and macrophytes were determined during...
Latest Results
Wed Apr 10, 2019 03:00
Environmental remediation processes by zero valence copper: reaction mechanisms
Abstract Recent studies have shown Cu(0) as a promising material for the removal of organic and inorganic pollutants. However, there is no review addressing the studies performed. This fact may be related to the toxicity of the particles and the copper released in solution that has not motivated researchers, which entails in a reduced number of publications. However, studies point out how to solve the problem of Cu deposition in support materials. In this work, a detailed review...
Latest Results
Wed Apr 10, 2019 03:00
α2,6-Sialylation promotes immune escape in hepatocarcinoma cells by regulating T cell functions and CD147/MMP signaling
Abstract Altered glycosylation is a common feature of cancer cells and plays an important role in tumor progression. β-Galactoside α2-6-sialyltransferase 1 (ST6Gal-I) is the critical sialyltransferase responsible for the addition of α2-6-sialic acid to the terminal N-glycans on the cell surface. However, the functions and mechanism of ST6Gal-I in tumor immune escape remain poorly understood. Here, we found that ST6Gal-I overexpression promoted hepatocarcinoma cell proliferation,...
Latest Results for Journal of Physiology and Biochemistry
Wed Apr 10, 2019 03:00
The beneficial effect of equine chorionic gonadotropin hormone (eCG) on the in vitro co-culture of bovine spermatogonial stem cell with Sertoli cells
Abstract Spermatogenesis is a complex developmental process that originates from spermatogonia stem cell. This process consists of sequential, highly organized steps of cell proliferation and differentiation resulting in the generation of functional spermatozoa. Many growth factors, hormones, and cell interactions of germ cells with Sertoli cells regulate these processes, and the failure of any of the processes can lead to male infertility The aim of the present study was to determine...
Latest Results for Comparative Clinical Pathology
Wed Apr 10, 2019 03:00
Irinotecan induces enterocyte cell death and changes to muc2 and muc4 composition during mucositis in a tumour-bearing DA rat model
Abstract Irinotecan-induced mucositis is a major oncological problem. Goblet cells secrete mucus, protecting the intestinal mucosa, with secretion altered during mucositis. The enteric nervous system is involved in regulating gut motility and secretion. The aim of this study was to determine whether enteric neural cells and goblet cells are altered following irinotecan treatment. Tumour-bearing Dark Agouti rats were administered a single dose of 175 mg/kg of irinotecan intraperitoneally...
Latest Results
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CDA and MTHFR polymorphisms are associated with clinical outcomes in gastroenteric cancer patients treated with capecitabine-based chemotherapy
Abstract Purpose The impact of pharmacogenetics on predicting survival in gastroenteric cancer remains unclear. Methods We tested 322 consecutive patients treated with capecitabine-based chemotherapy for CDA and MTHFR polymorphisms. Results Patients who...
Latest Results
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The impact of genetic polymorphism on CYP19A1 in androgen-deprivation therapy among Japanese men
Abstract Purpose Inadequate suppression of testosterone during androgen-deprivation therapy impairs its efficacy. This study investigated the significance of genetic polymorphism in CYP19A1, which encodes aromatase that catalyzes androgens into estrogens, among men treated with primary ADT for metastatic prostate cancer. Methods This study included...
Latest Results
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TGFβ receptor inhibitor galunisertib is linked to inflammation- and remodeling-related proteins in patients with pancreatic cancer
Abstract Purpose Galunisertib, the first small molecule transforming growth factor beta (TGFβ) receptor inhibitor, plus gemcitabine resulted in the improvement of survival in patients with unresectable pancreatic cancer, but markers to identify patients likely to respond are lacking. Methods In the Phase 1b/2 JBAJ study, 156 patients were randomized...
Latest Results
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The PVT1/miR-216b/Beclin-1 regulates cisplatin sensitivity of NSCLC cells via modulating autophagy and apoptosis
Abstract Purpose The efficacy of cisplatin-based chemotherapy remains an open question for chemo-resistance in non-small cell lung cancer (NSCLC). This study aimed to explore the role and mechanism of long noncoding RNA plasmacytoma variant translocation 1 (PVT1) in cisplatin sensitivity of NSCLC. Methods Paired tumor and adjacent tissues were...
Latest Results
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Pharmacokinetics and safety of olaparib tablets as monotherapy and in combination with paclitaxel: results of a Phase I study in Chinese patients with advanced solid tumours
Abstract Purpose Chinese patients have been enrolled in multiple Phase III trials of the poly(ADP-ribose) polymerase (PARP) inhibitor olaparib (Lynparza); however, the pharmacokinetic (PK) profile of olaparib has not been investigated in this population. This two-part, open-label Phase I study was, therefore, carried out to determine the PK and safety profile of olaparib (tablet formulation) in Chinese patients with advanced solid...
Latest Results
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Determination of melphalan in human plasma by UPLC–UV method
Abstract It is desirable to develop a fast method for quantification of melphalan due to its instability. Here we report a method for quantification of melphalan (MPL) in human plasma using a UPLC–PDA system. Briefly, 50 µL plasma sample was mixed with 25 µL internal standard (2500 ng/mL acetylmelphalan in methanol) and 25 µL 20% trichloroacetic acid, and centrifuged at 21,000 g (15,000 rpm) at 4 °C for 3 min. The supernatant (5 µL) was injected onto an Acquity™ BEH C18 LC column...
Latest Results
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Arsenic migration during co-processing of secondary residues from ammonium paratungstate production in cement kiln
Abstract To reduce the environmental pollution caused by ammonium paratungstate (APT) production in the Ganzhou area in China, simulated experiments in laboratory and field experiments in cement kilns were performed. The migration characteristics of As in secondary residues (thermometallurgy and hydrometallurgy residues) from APT production in cement kilns were similar, and As in the residues existed in the form of sulfides. When the residues were fed at the kiln inlet, the As...
Latest Results
Wed Apr 10, 2019 03:00
Single and combined effects of microplastics and roxithromycin on Daphnia magna
Abstract There is a rising concern about the pollution of microplastics (plastic particles < 5 mm) in water due to their physicochemical properties, especially their interaction with organic contaminants; however, such knowledge is still limited. The mass production and consumption of medication for the treatment of infectious diseases in human and animals have led to the ubiquity of antibiotics in the environment. We studied the single and joint effects of microplastics (1-μm...
Latest Results
Wed Apr 10, 2019 03:00
Protective effect of Astragaloside IV to inhibit thiram-induced tibial dyschondroplasia
Abstract Tibial dyschondroplasia (TD) is most the common tibiotarsal bone disease in rapidly growing birds throughout the world. There is accumulating evidence that COX-2 abnormal expression in tibia plays an important role in TD progression. So, the regulation of COX-2 is an ever more appealing target for therapeutic intervention in TD. Astragaloside IV has an indispensable role in maintaining COX-2 expression in many diseases. So, we designed this study to use Astragaloside IV...
Latest Results
Wed Apr 10, 2019 03:00
Effects of different substrates on nitrogen and phosphorus removal in horizontal subsurface flow constructed wetlands
Abstract This study aimed to explore the nitrogen and phosphorus removal performance of the horizontal submerged constructed wetland (HSCW) with Ti-bearing blast furnace slag (T). Another two HSCWs, with the converter steelmaking slag (G) and the stone (S) as wetland substrates, respectively, were simultaneously running as control. The results showed that the nitrogen and phosphorus removal capacities of the T-HSCW were generally better than those of another two HSCWs. When the...
Latest Results
Wed Apr 10, 2019 03:00
Clinical significance of incidentally discovered renal cysts in pediatric patients
Abstract Purpose To determine the clinical significance of incidentally discovered renal cysts in pediatric patients and identify imaging predictors of autosomal dominant polycystic kidney disease (ADPKD). Methods A retrospective search of radiology reports from 2000 to 2016 was performed to identify patients < 18 years old with an imaging exam identifying...
Latest Results for Abdominal Imaging
Wed Apr 10, 2019 03:00
Profile of chlorophylls and carotenoids of wheat ( Triticum aestivum L.) and barley ( Hordeum vulgare L.) microgreens
Abstract The use of cereal microgreens is increasing because of increased consumer's interest in healthier products. Chlorophyll (Chl) and Carotenoids (Car) are suggested to correlate with health promoting components like phenolics and antioxidant potential of the plant-part. They also play role against clinical conditions like thalassemia and hemolytic anemia and reduce the risk of some chronic diseases, such as cancer, cardiovascular diseases, skin diseases and age-related eye...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Improvement of cooking quality of germinated brown rice attributed to the fissures caused by microwave drying
Abstract Germinated brown rice (GBR) contains rich bio-active components, but has poor edible quality. To improve the cooking quality of GBR, fissure generation in kernels caused by microwave drying were investigated considering cooking properties, microstructure and textural attributes. The microwave intensity had significant effects on the fissure percentage of GBR, and microwave intensity of 3–4 W/g may be suitable for the microwave drying of GBR based on the distribution of...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Mechanisms and in vitro models of drug-induced cholestasis
Abstract Cholestasis underlies one of the major manifestations of drug-induced liver injury. Drug-induced cholestatic liver toxicity is a complex process, as it can be triggered by a variety of factors that induce 2 types of biological responses, namely a deteriorative response, caused by bile acid accumulation, and an adaptive response, aimed at removing the accumulated bile acids. Several key events in both types of responses have been characterized in the past few years. In...
Latest Results for Archives of Toxicology
Wed Apr 10, 2019 03:00
Parental internet search in the field of pediatric orthopedics
Abstract Parents whose children are affected by systemic diseases, anomalies, deformities, or further orthopedic defective positions use the Internet to increase their knowledge. However, there have been few studies that focus, as this one does, on Internet enquiries done before the parents contact the pediatric orthopedic surgeon. This study analyzed data gathered through a standardized questionnaire on general habits of Internet use, parents' hardware, age, and educational background...
Latest Results for European Journal of Pediatrics
Wed Apr 10, 2019 03:00
Clinical Practice Guideline of Integrative Chinese and Western Medicine for Acute Myocardial Infarction
Abstract With increasing morbidity and mortality, acute myocardial infarction (AMI) has become one of the major causes of human death, leading to heavy burdens to individuals, families and society. Previous researches have found that though large amount of resources and great effort were devoted, no significant improvements were achieved in reducing the in-hospital mortality of AMI patients. Meanwhile, extensive studies about Chinese medicine (CM) have found that CM has special...
Latest Results for Chinese Journal of Integrative Medicine
Wed Apr 10, 2019 03:00
Paracentral Acute Middle Maculopathy Treated with Acupuncture: A Case Report
Latest Results for Chinese Journal of Integrative Medicine
Wed Apr 10, 2019 03:00
Retroperitoneal soft tissue sarcoma: low-dose neoadjuvant radiation therapy followed by surgery with or without intraoperative radiotherapy and adjuvant radiation therapy
Abstract Background We describe the clinical history, outcome, and toxicity of five patients with high-grade retroperitoneal soft tissue sarcoma (RSTS) who were treated with neoadjuvant low-dose radiotherapy (RT) followed by resection with or without intraoperative radiotherapy (IORT), followed by adjuvant RT. We aim to provide additional evidence for the various treatment options that exist for this rare tumor entity. ...
Latest Results
Wed Apr 10, 2019 03:00
Impacts of earthworm species on soil acidification, Al fractions, and base cation release in a subtropical soil from China
Abstract Soil-exchangeable aluminum (Al) has toxic effects on living organisms in acidic soils. Earthworm presence and activity can alter soil pH, which has a significant influence on Al toxicity. However, the effects of earthworms on soil Al toxicity and fractions are still largely unknown. This laboratory study focused on the effects of three earthworm species (endogeics Pontoscolex corethrurus and Amynthas robustus, anecis Amynthas aspergillum) on soil acidification, Al fraction...
Latest Results
Wed Apr 10, 2019 03:00
Effect of selenium on the subcellular distribution of cadmium and oxidative stress induced by cadmium in rice ( Oryza sativa L.)
Abstract Cadmium (Cd) is absorbed readily by rice plants and is transferred to humans when contaminated rice is consumed. Adding selenium (Se) to the plant nutrient solutions reduces the accumulation of Cd in the rice (Oryza sativa L.) seedlings. However, as the relevant underlying mechanism remains unclear, the aim of our study was to improve our understanding of the Se-mediated resistance to Cd stress in rice. We conducted hydroponic experiments to study the effects of selenite...
Latest Results
Wed Apr 10, 2019 03:00
A scale-adaptive method for urban rainwater harvesting simulation
Abstract At a building or dwelling scale, accurate evaluation of the water savings potential from rainwater harvesting (RWH) can be achieved by simulating the performance of the RWH system using a balance equations model. At an urban scale, water savings potential is usually estimated from the balance between the annual rainfall and annual water consumption. This approach has limited accuracy since it assumes an infinite storage capacity and it disregards the variability of the...
Latest Results
Wed Apr 10, 2019 03:00
Promotion of circular economy: steelwork dusts as secondary raw material in conventional mortars
Abstract Among the actions proposed by the European Union for the implementation of Circular Economy is the use of waste as a secondary raw material (SRM). During the fusion of the scrap, a steel dust is generated, named electric arc furnace dust (EAFD). The EAFD is composed mainly of potentially leachable heavy metals and is classified as a "hazardous" waste. Worldwide, approximately 70% of EAFD is deposited in landfills, with a previous treatment through cement-based materials...
Latest Results
Wed Apr 10, 2019 03:00


Modification of acidic and textural properties of a sulphated zirconia catalyst for efficient conversion of high-density polyethylene into liquid fuel
Abstract Consumption of plastic has a rapid increase of about 8% per annum and reached to 400 million per tonnes approximately, where about 50% of plastic was disposed after using only once. Different techniques for treating this increased waste faced a number of issues related to cost and environmental and sustainable development. Catalytic conversion has been found as one of the most viable solutions to solve this problem. Sulphated zirconia (SZ) catalyst modified with calcium...
Latest Results
Wed Apr 10, 2019 03:00
An empirical model on the impact of foreign direct investment on China's environmental pollution: analysis based on simultaneous equations
Abstract This paper analyses the link between foreign direct investment (FDI) and economic growth and their subsequent impact on environmental pollution in China. The simultaneous equation method was used with data from 31 provinces in China covering the period between 1995 and 2016. The findings indicate that the effect of FDI on economic growth, industrial structure, and environmental pollution control positively impacts on China's industrial pollution control and environmental...
Latest Results
Wed Apr 10, 2019 03:00
Production of prebiotic gluten-free bread with red rice flour and different microbial transglutaminase concentrations: modeling, sensory and multivariate data analysis
Abstract The aim of this study was to develop gluten-free bread formulated with red rice flour and microbial transglutaminase and prebiotic (inulin). First, the physicochemical analysis of minerals present in red rice flour was performed. Response surface methodology was used to analyze the effects of microbial transglutaminase (MTgase) [0.5; 1.0 and 1.5%] in combination with fermentation time (FT) [60; 80 and 100 min] on the quality parameters of gluten-free bread. Acceptance...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Evaluation of pasting and dough rheological properties of composite flours made from flour varied in gluten strength
Abstract Flours from various wheat varieties varied in gluten strength were blended in varying proportions and evaluated for pasting and dough rheological properties. The different blends of strong: very weak/weak/medium flour (100:0, 75:25, 50:50, 25:75 and 0:100) (w/w) were prepared. Two strong and three weak wheat varieties were selected for this study on the basis of Farinograph dough stability (DS). Strong wheat (HUW468 and HP1761), medium weak (HUW234), weak (HD2894) and...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Pervaporation-based membrane processes for the production of non-alcoholic beverages
Abstract Nowadays, the interest in manufacturing non-alcoholic or low alcoholic content beverages from alcoholic beverages is a current challenge for food technologists; this is due to the fact that huge consumption of alcoholic beverages may produce health problems in the costumers. In principle, the post-fermentation ethanol removal from alcoholic beverages is carried out by means of evaporation or distillation. Such current dealcoholization methodologies are efficiently removing...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Chemical composition of fennel seed extract and determination of fenchone in commercial formulations by GC–MS method
Abstract In the present study, various phytoconstituents of methanolic extract of Foeniculum vulgare were identified using gas-chromatography mass spectrometry (GC–MS) method. GC–MS method was also applied for the analysis of biomarker fenchone in extract and eight different commercial formulations. The mass of prepared extract and formulations A–D and H (commercial herbal mixtures and commercial extract) used for the analysis of fenchone was 10 g. However, the mass of formulations...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Impact of roasting and extraction methods on chemical properties, oxidative stability and Maillard reaction products of peanut oils
Abstract This study was designed to investigate the influence of dry air roasting (140, 160 and 180 °C for 5 and 10 min) and extraction methods (solvent and mechanical) on peanut oil quality characteristics. Oil yield, oxidative stability index (OSI), radical scavenging activity (RSA), and Maillard reaction products were increased while peroxide value (PV) and conjugated dienes were decreased in oil of peanuts roasted at 180 °C for 10 min. Oils extracted mechanically from roasted...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Differentiation of honeydew honeys and blossom honeys: a new model based on colour parameters
Abstract The present study aimed to differentiate Mimosa scabrella Bentham (bracatinga) honeydew honeys from blossom honeys, with and without addition of heat treatment, and bracatinga honeydew honeys adulterated with blossom honeys (5, 15 and 25% of blossom honeys), using chromatic characterization associated with chemometric analysis. Bracatinga honeydew honeys presented unusual chromatic characteristics which allowed differentiation of blossom honeys by principal components...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
Evaluation of biogenic amines and nitrate in raw and pickled jurubeba ( Solanum paniculatum L.) fruit
Abstract The presence of biogenic amines, such as histamine and tyramine, in pickled food can cause health problems, such as allergies. However, other bioactive amines may be present and can induce some diseases. Some biogenic amines can react with nitrate and form nitrosamines, compounds harmful to human health. In this research, we qualitatively and quantitatively evaluated some biogenic amines and nitrate content in jurubeba preserved in oil or vinegar. The fruits were obtained...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
The comparison of accuracy of ultrasonographic features versus ultrasound-guided fine-needle aspiration cytology in diagnosis of malignant thyroid nodules
Abstract Purpose To compare the diagnostic accuracy of sonographic features with ultrasound-guided fine-needle aspiration (FNA) cytology in the detection of malignant thyroid nodules. Methods This analytical cross-sectional study was conducted on patients with the diagnosis of thyroid nodule, who underwent ultrasound-guided FNA in Shahid Beheshti teaching...
Latest Results
Wed Apr 10, 2019 03:00
Dissolution Chamber for Small Drug Delivery System in the Periodontal Pocket
Abstract Existing dissolution chambers have relatively large volume compared to the size of the periodontal pocket. A small volume dissolution method that simulates the physiological release environment for periodontal drug delivery is needed. The objectives were to construct a small, more physiologically relevant, dissolution chamber and investigate the properties of the new dissolution chamber for the assessment of sustained drug release systems in periodontal delivery. Flow-through...
Latest Results for The AAPS Journal
Wed Apr 10, 2019 03:00
Osteoma of external auditory canal associated with external auditory canal cholesteatoma and exuberant granulation tissue in mastoid air cell system: a rare association
Abstract Osteoma of EAC is a rare tumour. Cholesteatoma of EAC associated with osteoma is consequence of osteoma of EAC. Its incidence is rare and very few cases have been reported in the literature. Its association with exuberant granulation tissue in the mastoid air cell system without extension of Cholesteatoma into middle ear cleft is even rare. This association has been reported for the first time as evident from review of literature.
Otolaryngology Indian
Wed Apr 10, 2019 03:00
The effect of harvest time and varieties on total phenolics, antioxidant activity and phenolic compounds of olive fruit and leaves
Abstract The effect of harvest periods on total phenol, antioxidant activity, individual phenolic compounds of fruit and leaves of Tavşan Yüreği, Memecik, Edremit, Ayvalık and Gemlik olive varieties grown in Turkey were investigated. The highest total phenol (317.70 mg/100 g and 2657.81 mg/100 g) were observed in Tavşan Yüreği olive fruit and Ayvalık leaves harvested in December, respectively. The highest antioxidant activities (83.84%) were determined in Edremit fruit harvested...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
A novel approach using low-cost Citrus limetta waste for mixotrophic cultivation of oleaginous microalgae to augment automotive quality biodiesel production
Abstract The present study reports the use of Citrus limetta (CL) residue for cultivating Chlorella sp. mixotrophically to augment production of biodiesel. The cultivation of Chlorella sp. using CL as media was carried out by employing a fed-batch technique in open tray (open tray+CL) and in software (BioXpert V2)–attached automated photobioreactor (PBR+CL) systems. Data showed the limit of nitrogen substituent and satisfactory organic source of carbon (OSC) in CL, causing > 2-fold...
Latest Results
Wed Apr 10, 2019 03:00
Clinical impact of PD-L1 and PD-1 expression in squamous cell cancer of the vulva
Abstract Purpose Squamous cell carcinoma of the vulva (SQCV) is the fifth most common cancer in women and accounts for about 5% of all genital cancers in women. The PD-L1 signaling pathway is activated in many malignant neoplasms and its blockade enhances anti-cancer immunity. The aim of our study was to examine the protein expression of PD-L1 and PD-1 in squamous cell cancer of the vulva, its correlations with clinicopathologic features...
Latest Results
Wed Apr 10, 2019 03:00
Consolidative mediastinal irradiation of malignant lymphoma using active scanning proton beams: clinical outcome and dosimetric comparison
Abstract Purpose Current research approaches in lymphoma focus on reduction of therapy-associated long-term side effects. Especially in mediastinal lymphoma, proton beam radiotherapy (PT) may be a promising approach for reducing the dose to organs at risk (OAR). Patients In total, 20 patients were irradiated with active scanning PT at Heidelberg Ion Beam...
Latest Results
Wed Apr 10, 2019 03:00
Flavonoids in common and tartary buckwheat hull extracts and antioxidant activity of the extracts against lipids in mayonnaise
Abstract Buckwheat hulls, generally discarded as waste, have been known to possess various flavonoids and high antioxidant activities. The objective of this study was to determine effect of extracting solvents [water, ethanol (20%, 50%, 80%, and 100%), methanol, and acetone] on total phenolic content, flavonoid content and composition, and antioxidant activities of common and tartary buckwheat hull extracts. Antioxidative effect of common and tartary buckwheat hull extracts on...
Latest Results for Journal of Food Science and Technology
Wed Apr 10, 2019 03:00
The lost dimension: pruned plants in Roman gardens
Abstract This paper focuses on evidence for the pruning and dwarfing of plants represented in Roman garden paintings. In two particularly fine examples of this type, from the Villa of Livia at Prima Porta near Rome, and the House of the Golden Bracelet at Pompeii, the artists have carefully portrayed pruning marks and other horticultural practices that alter the size and natural habit of plants. This evidence complements archaeobotanical findings by showing the above-ground appearance...
Latest Results
Wed Apr 10, 2019 03:00

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