Palate ulcer, uvular destruction and nasal septal perforation caused by Sporothrix brasiliensis in an HIV-infected patient.

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Palate ulcer, uvular destruction and nasal septal perforation caused by Sporothrix brasiliensis in an HIV-infected patient.

Med Mycol Case Rep. 2019 Mar;23:16-19

Authors: Eyer-Silva WA, de Azevedo MCVM, da Silva GAR, Basílio-de-Oliveira RP, de Araujo LF, do Lago IV, Pereira FCF, Fernandes MBT, Figueiredo-Carvalho MHG, Souza Rabello VB, Zancopé-Oliveira RM, Almeida-Paes R, Ferry FRA, Neves-Motta R

Abstract
Sporotrichosis is a human and animal disease caused by dimorphic pathogenic species of the genus Sporothrix. We report a dramatic presentation of Sporothrix brasiliensis infection, with destruction of the nasal septum, soft palate, and uvula of an HIV-infected woman. She was successfully treated with amphotericin B deoxycholate followed by itraconazole. Sporotrichosis remains a neglected opportunistic infection in patients with AIDS and awareness of this potentially fatal infection is of utmost importance.

PMID: 30479942 [PubMed]

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