Intranodal lymphangiography with thoracic duct embolization for the treatment of chyle leaks after head and neck cancer surgery

xlomafota13 shared this article with you from Inoreader Intranodal lymphangiography with thoracic duct embolization for the treatment of chyle leaks after head and neck cancer surgery Via Head & Neck Abstract Background Thoracic duct injury is a rare complication of head and neck surgery. Thoracic duct embolization (TDE) has been proposed to manage postoperative chyle leaks. Methods Twelve patients who underwent lymphangiography for a chyle leak after head and neck surgery (M:F = 5:7, mean 55 years) were retrospectively reviewed. Lymphangiographic findings, technical success, complications, and clinical outcomes were analyzed. Results Chyle leak was identified and TDE attempted in 11 of 12 patients. Three patients required repeat TDE. Technical success of TDE was 86% (12/14). Clinical success for patients with technically successful TDE was 90% (9/10). Median time until drain removal was 2.1 days in nine patients with clinical success. Two major complications were encountered, chylothorax after initial TDE, requiring additional TDE and in one case surgical TD ligation. Conclusions TDE is a safe treatment for chyle leaks after head and neck surgery with high technical and clinical success rates. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Low‐risk human papilloma virus positive oropharyngeal cancer with one positive lymph node: Equivalent outcomes in patients treated with surgery and radiation therapy versus surgery alone

xlomafota13 shared this article with you from Inoreader Low‐risk human papilloma virus positive oropharyngeal cancer with one positive lymph node: Equivalent outcomes in patients treated with surgery and radiation therapy versus surgery alone Via Head & Neck Abstract Background For human papilloma virus positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC), management recommendations for patients with a single metastatic lymph node <6 cm in diameter remain nebulous, leading to treatment heterogeneity in this common subgroup of patients. Methods We utilized the National Cancer Database to perform survival and multivariable analyses of patients with HPV+ OPSCC with one positive lymph node <6 cm and negative surgical margins. Results We found that 5‐year survival is comparable between patients who receive surgery and adjuvant radiation versus surgery alone. In multivariable analyses, we found no significant difference in the hazard ratio of overall survival after adjusting for various potential confounders. Conclusions These data suggest that patients with margin‐negative HPV+ OPSCC with a single positive lymph node <6 cm have comparable survival with or without adjuvant radiation. Future studies exploring outcomes for this specific group in randomized‐controlled trials will be critical for further evaluating these initial observations. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Risk of second primary malignancy after minor salivary gland cancer

xlomafota13 shared this article with you from Inoreader Risk of second primary malignancy after minor salivary gland cancer: A Surveillance, Epidemiology, and End Results database analysis Via Head & Neck Abstract Background Minor salivary gland cancer (MiSGC) is a group of tumors with varied disease course in the head and neck. We evaluated the risk of a second primary malignancy (SPM) in MiSGC patients and identified possible prognostic factors for survival using a large population database. Methods We used the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) data to evaluate the risk and prognosis of SPM in patients diagnosed with MiSGC. Results The risk of SPM increased in MiSGC patients compared with the endemic rate. The risk of SPM was slightly greater in female patients and who underwent radiotherapy. Age at primary diagnosis, sex, race, year of diagnosis, SEER stage, radiotherapy, SPM, histology, and tumor site were significant survival prognostic indicators of MiSGC patients. Conclusion Radiotherapy and female sex were risk factors for SPM after MiSGC. Long‐term surveillance for SPM was important in MiSGC patients. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Association Between Interleukin-6 and Head and Neck Squamous Cell Carcinoma: A Systematic Review.

xlomafota13 shared this article with you from Inoreader Association Between Interleukin-6 and Head and Neck Squamous Cell Carcinoma: A Systematic Review. Via pubmed: "clin exp otorhinola... Related Articles Association Between Interleukin-6 and Head and Neck Squamous Cell Carcinoma: A Systematic Review. Clin Exp Otorhinolaryngol. 2021 Feb;14(1):50-60 Authors: Uz U, Eskiizmir G Abstract Interleukin-6 (IL-6) is a proinflammatory cytokine which plays an important role in several regulatory mechanisms of cancer. Moreover, experimental and clinical studies have reported that IL-6 targeted therapies might provide significant benefits for cancer treatment. The purpose of this systematic review is to evaluate IL-6 activity in patients with head and neck squamous cell carcinoma (HNSCC). A systematic review of the association between serum, saliva and tumor IL-6 and HNSCC was developed on PubMed/Medline in the publication range from January 1995 to January 2019. Our literature analysis demonstrated that overexpression and elevated serum and/or saliva IL-6 concentrations in patients with HNSCC are related to poor survival and oncological outcomes. Although there is a correlation between IL-6 concentrations and tumorigenicity, it is noteworthy that IL-6 targeted therapies are generally performed in vitro and in experimental studies. Therefore, prospective, randomized c linical trials are required that focus on IL-6 targeted therapies for the treatment of HNSCC. PMID: 33587847 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Eccrine Hidradenoma of the Nasal Vestibule

xlomafota13 shared this article with you from Inoreader Eccrine Hidradenoma of the Nasal Vestibule: A Rare Clinical Entity. Via ear nose throat Related Articles Eccrine Hidradenoma of the Nasal Vestibule: A Rare Clinical Entity. Ear Nose Throat J. 2021 Feb 15;:145561321995018 Authors: Cheon YI, Kim SD, Choi KU, Cho KS Abstract Eccrine hidradenoma is a relatively rare benign tumor of sweat gland origin but with possible malignant transformation. It usually consists of solitary, well-demarcated papules or nodules covered with normal skin. Common sites of involvement are the scalp, face, limbs, and anterior trunk. Although the lining of the nasal vestibule includes hair follicles, sebaceous glands, and sweat glands, an eccrine hidradenoma originating in the nasal vestibule has yet to be reported. Herein, we describe a rare clinical presentation of nasal eccrine hidradenoma, treated successfully using a transnasal endoscopic approach. PMID: 33587647 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Safe Removal of a Centipede From the Ear By Using an Innovative Practicable Method: A Case Report.

xlomafota13 shared this article with you from Inoreader Safe Removal of a Centipede From the Ear By Using an Innovative Practicable Method: A Case Report. Via ear nose throat Related Articles Safe Removal of a Centipede From the Ear By Using an Innovative Practicable Method: A Case Report. Ear Nose Throat J. 2021 Feb 15;:145561321995010 Authors: Ding MC, Tsai YT, Tsai MS, Hsu CM, Chang GH Abstract Arthropods may become lodged inside the ear and cause considerable emotional and physical trauma. Cases of centipedes being lodged in the external auditory canal have rarely been reported. In this article, we present the case of woman who had a centipede lodged inside her right external auditory canal. Removal using a topical local anesthetic can lead to vigorous activity of the centipede, which can cause harm to the patient and clinicians. Therefore, we developed and successfully applied a practicable method that involved using a modified plastic bottle for safe centipede removal. In conclusion, centipedes can express distinct and threatening behavior, and clinicians should pay attention to the activity of the lodged centipede and possibly use the proposed method to safely remove it. PMID: 33587651 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Trichofolliculoma in the Auricle.

xlomafota13 shared this article with you from Inoreader Trichofolliculoma in the Auricle. Via ear nose throat Related Articles Trichofolliculoma in the Auricle. Ear Nose Throat J. 2021 Feb 15;:145561321995599 Authors: Lee HY, Kim EK, Choi HS, Jeong J PMID: 33587670 [PubMed - as supplied by publisher] View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.