Blog Archive

Αλέξανδρος Γ. Σφακιανάκης

Tuesday, May 11, 2021

Can We Conquer Advanced Head and Neck Cancer? Current Status and Future Directions

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Clin Exp Otorhinolaryngol. 2021 May;14(2):145-146. doi: 10.21053/ceo.2021.00458. Epub 2021 Apr 30.

NO ABSTRACT

PMID:33971695 | DOI:10.21053/ceo.2021.00458

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The Choice of Anesthetic Agents for Endoscopic Sinus Surgery: Can Sinus Surgeons Be Involved?

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Clin Exp Otorhinolaryngol. 2021 May;14(2):147-148. doi: 10.21053/ceo.2021.00395. Epub 2021 Apr 30.

NO ABSTRACT

PMID:33971696 | DOI:10.21053/ceo.2021.00395

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Length of the Cricoid and Trachea in Children: Predicting Intubation Depth to Prevent Subglottic Stenosis

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Objective

Define the length of the subglottis and trachea in children to predict a safe intubation depth.

Methods

Patients <18 years undergoing rigid bronchoscopy from 2013 to 2020 were included. The carina and inferior borders of the cricoid and true vocal folds were marked on a bronchoscope and distances were measured. Patient age, weight, height, and chest height were recorded. Four styles of cuffed pediatric endotracheal tubes (ETT) were measured and potential positions of each cuff and tip were calculated within each trachea using five depth of intubation scenarios. Multivariate linear regression was performed to identify predictors of subglottic and tracheal length.

Results

Measurements were obtained from 210 children (141 male, 69 female), mean (SD) age 3.21 (3.66) years. Patient height was the best predictor of subglottic length (R 2: 0.418): Length sg (mm) = 0.058 * height (cm) + 2.8, and tracheal length (R 2: 0.733): Length t (mm) = 0.485 * height (cm) + 21.3. None of the depth of intubation scenarios maintained a cuff‐free subglottis for all ETT styles investigated. A formula for depth of intubation: Length di (mm) = 0.06 * height (cm) + 8.8 found that no ETT cuffs would be in the subglottis and all tips would be above the carina.

Conclusion

Current strategies for determining appropriate depth of intubation pose a high risk of subglottic ETT cuff placement. Placing the inferior border of the vocal cords 0.06 * height (cm) + 8.8 from the superior border of the inflated ETT cuff may prevent subglottic cuff placement and endobronchial intubation.

Level of Evidence

4 Laryngoscope, 2021

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A Comparison of an Artificial Intelligence Tool to Fundamental Frequency as an Outcome Measure in People Seeking a More Feminine Voice

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Objectives/Hypothesis

An artificial intelligence (AI) tool was developed using audio clips of cis‐male and cis‐female voices based on spectral analysis to assess %probability of a voice being perceived as female (%Prob♀). This program was validated with 92% accuracy in cisgender speakers. The aim of the study was to assess the relationship of f o on %Prob♀ by a validated AI tool in a cohort of trans females who underwent intervention to feminize their voice with behavioral modification and/or surgery.

Study Design

Cohort study.

Methods

Fundamental frequency (f o) from prolonged vowel sounds (f o/a/) and f o from spontaneous speech (f o‐sp) were measured using the Kay Pentax Computerized Speech Lab (Montvale, NJ) in trans females postintervention. The same voice samples were analyzed by the AI tool for %Prob♀. Chi‐square analysis and regression models were performed accepting >50% Prob♀ as female voice.

Results

Forty‐two patients were available for analysis after intervention. f o‐sp post‐treatment was positively correlated with %Prob♀ (R = 0.645 [P < .001]). Chi‐square analysis showed a significant association between AI %Prob♀ >50% for the speech samples and f o‐sp >160 Hz (P < .01). Sixteen of 42 patients reached an f o‐sp >160 Hz. Of these, the AI program only perceived nine patients as female (>50 %Prob♀).

Conclusion

Patients with f o‐sp >160 Hz after feminization treatments are not necessarily perceived as having a high probability of being female by a validated AI tool. AI may represent a useful outcome measurement tool for patients undergoing gender affirming voice care.

Level of Evidence

3 Laryngoscope, 2021

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Intratympanic Steroid Injection Complicated by Iatrogenic Perilymphatic Fistula: A Cautionary Tale

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Intratympanic (IT) steroid therapy is a mainstay treatment for sudden sensorineural hearing loss (SSNHL) for both initial therapy and salvage therapy. We report a rare case of iatrogenic perilymphatic fistula that resulted from trauma during an IT steroid injection for SSNHL. We discuss the diagnosis and treatment in the current case and compare it with previous reports from the literature. Laryngoscope, 2021

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Recognizing oneself in the encounter with others: Meaningful moments in systemic therapy for social anxiety disorder in the eyes of patients and their therapists after the end of therapy

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journal.pone.0250094.t002&size=inline

by Rebecca Hilzinger, Javiera Duarte, Barbara Hench, Christina Hunger, Jochen Schweitzer, Mariane Krause, Martina Fischersworring

Objective

The objective of this study is to characterize and describe meaningful moments in the context of systemic psychotherapy, from the point of view of patients and their therapists, after the end of therapy. The therapy studied is a manualized, monitored systemic therapy for social anxiety disorder.

Method

Semi-structured follow-up interviews were conducted separately with five patients and their therapists (N = 10). Methodological triangulation was used: Grounded theory was used to code the transcripts as described by Charmaz. Then the passages of the selected code "meaningful moment" were evaluated using thematic comparison, in line with Meuser & Nagel.

Findings

Three categories involving meaningful moments were identified: (1) meeting other patients in group therapy session, (2) therapeutic resource orientation and (3) recognizing oneself in a diagnosis or pattern of behaviour. These categories emerged as contexts related to the occurrence of meaning ful moments from a subjective perspective.

Discussion

Meaningful moments seem to be consistently related to the therapist input and to specific interventions or settings, both from the perspective of the patients and the therapists. Two tandems each described a coincident moment. One central aspect of all 14 moments is that the patients and therapists described patients being able to acquire another outlook on themselves.

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COVID-19 and periodontitis: reflecting on a possible association

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Recent studies have demonstrated a relationship between the severe clinical course of COVID-19 and other chronic diseases such as: cardiovascular disease, hypertension, diabetes mellitus, obesity and chronic r...
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