Blog Archive

Αλέξανδρος Γ. Σφακιανάκης

Tuesday, July 30, 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Injection laryngoplasty as adjunct treatment method for muscle tension dysphonia: Preliminary findings...
Injection laryngoplasty as adjunct treatment method for muscle tension dysphonia: Preliminary findingsDaniel Novakovic FRACS, MBBS, MPH, BSc  Duong Duy Nguyen MD, PhD  Antonia Chacon BAppSc (SpPath) Hons, CPSP  Catherine Madill PhD, CPSPFirst published: 30 July 2019 https://doi.org/10.1002/lary.28205Editor's Note: This Manuscript was accepted for publication on July 9, 2019.Presented at the American Laryngological Association's 2019 Spring Meeting at COSM in Austin, Texas, U.S.A., May 1–3, 2019.This...
Medicine by Alexandros G. Sfakianakis
08:58
Inducible laryngeal obstruction: Endoscopic quantitative analysis of glottic aperture Paulo Henrique...
Inducible laryngeal obstruction: Endoscopic quantitative analysis of glottic aperturePaulo Henrique Peitl Gregorio MD  Juliana Teixeira Gomes MBBS  Roberto Rodrigues MD, PhD  Marcia Jacomelli MD, PhD  Ellen Samara Santos MBBS  Marcelo Gervilla Gregorio MD, PhDFirst published: 30 July 2019 https://doi.org/10.1002/lary.28213The authors have no funding or conflicts of interest to disclose.We thank our colleagues from Respsono Clinic who assisted the research throughout the entire process of development...
Medicine by Alexandros G. Sfakianakis
08:58
Predictive value of the ACS NSQIP calculator for head and neck reconstruction free tissue transfer...
Predictive value of the ACS NSQIP calculator for head and neck reconstruction free tissue transferWilliam Tierney MD  Janki Shah MD  Kate Clancy MD  Maxwell Y. Lee BS  Peter J. Ciolek MD  Michael A. Fritz MD  Eric D. Lamarre MDFirst published: 30 July 2019 https://doi.org/10.1002/lary.28195Editor's Note: This Manuscript was accepted for publication on July 5, 2019.The authors have no funding, financial relationships, or conflicts of interest to disclose.Read the full textePDFPDFTOOLS SHAREAbstractBackgroundPredictive...
Medicine by Alexandros G. Sfakianakis
08:57
Slide laryngotracheoplasty for congenital subglottic stenosis in newborns and infants László Rovó MD,...
Slide laryngotracheoplasty for congenital subglottic stenosis in newborns and infantsLászló Rovó MD, PhD  Eszter Erdélyi MD  Zoltán Tóbiás MD  Péter Gál MD  Ilona Szegesdi MD  Balázs Sztanó MD, PhD  Kishore Sandu MD  Ádám Bach MD, PhDFirst published: 27 July 2019 https://doi.org/10.1002/lary.28192Editor's Note: This Manuscript was accepted for publication on June 27, 2019.The authors have no funding, financial relationships, or conflicts of interest to disclose.Read the full textePDFPDFTOOLS SHAREAbstractObjectivesSubglottic...
Medicine by Alexandros G. Sfakianakis
08:57
Awake thyroidectomy Thorsen W. Haugen MD  Luke N. Andera MD  Archie B. LaMadrid MD First published:...
Awake thyroidectomyThorsen W. Haugen MD  Luke N. Andera MD  Archie B. LaMadrid MDFirst published: 30 July 2019 https://doi.org/10.1002/lary.28196Editor's Note: This Manuscript was accepted for publication on July 5, 2019.The authors have no funding, financial relationships, or conflicts of interest to disclose.Read the full textePDFPDFTOOLS SHAREAbstractObjectiveIn this article, we present a series of 28 patients who underwent thyroid surgery using local anesthesia. We describe our technique, report...
Medicine by Alexandros G. Sfakianakis
08:57
Management of arteriovenous malformation of the ear: A protocol for resection and reconstruction Marina...
Management of arteriovenous malformation of the ear: A protocol for resection and reconstructionMarina Vilela Chagas Ferreira MD  Dov Charles Goldenberg MD, PhD  Vania Kharmandayan MD  Rolf Gemperli MD, PhDFirst published: 29 July 2019 https://doi.org/10.1002/lary.28209Editor's Note: This Manuscript was accepted for publication on July 10, 2019.The authors have no funding, financial relationships, or conflicts of interest to disclose.Read the full textePDFPDFTOOLS SHAREAbstractObjectiveArteriovenous...
Medicine by Alexandros G. Sfakianakis
08:53
MDPI Journals
Molecules, Vol. 24, Pages 2778: Hypotensive Snake Venom Components—A Mini-ReviewMolecules, Vol. 24, Pages 2778: Hypotensive Snake Venom Components—A Mini-Review Molecules doi: 10.3390/molecules24152778 Authors: Orsolya Péterfi Francisc Boda Zoltán Szabó Elek Ferencz László Bába Hypertension is considered a major public health issue due to its high prevalence and subsequent risk of cardiovascular and kidney diseases. Thus, the search for new antihypertensive compounds remains of great interest. Snake...
Medicine by Alexandros G. Sfakianakis
08:52
Viruses, Vol. 11, Pages 695: Experimental Assessment of Zika Virus Mechanical Transmission by...
Viruses, Vol. 11, Pages 695: Experimental Assessment of Zika Virus Mechanical Transmission by Aedes AegyptiViruses, Vol. 11, Pages 695: Experimental Assessment of Zika Virus Mechanical Transmission by Aedes Aegypti Viruses doi: 10.3390/v11080695 Authors: Antoine Boullis Nadège Cordel Cécile Herrmann-Storck Anubis Vega-Rúa The pandemic emergence of several mosquito-borne viruses highlights the need to understand the different ways in which they can be transmitted by vectors to human hosts. In this...
Medicine by Alexandros G. Sfakianakis
08:49
Nutrients, Vol. 11, Pages 1756: Social Jet Lag Associates Negatively with the Adherence to the...
Nutrients, Vol. 11, Pages 1756: Social Jet Lag Associates Negatively with the Adherence to the Mediterranean Diet and Body Mass Index among Young AdultsNutrients, Vol. 11, Pages 1756: Social Jet Lag Associates Negatively with the Adherence to the Mediterranean Diet and Body Mass Index among Young Adults Nutrients doi: 10.3390/nu11081756 Authors: Zerón-Rugerio Cambras Izquierdo-Pulido Obesity and unhealthy eating habits have been associated with irregular sleep–wake patterns during the week, also...
Medicine by Alexandros G. Sfakianakis
08:48
Microorganisms, Vol. 7, Pages 225: Oxidative Stress Response of Aspergillus oryzae Induced by...
Microorganisms, Vol. 7, Pages 225: Oxidative Stress Response of Aspergillus oryzae Induced by Hydrogen Peroxide and Menadione Sodium BisulfiteMicroorganisms, Vol. 7, Pages 225: Oxidative Stress Response of Aspergillus oryzae Induced by Hydrogen Peroxide and Menadione Sodium Bisulfite Microorganisms doi: 10.3390/microorganisms7080225 Authors: Shao Tu Wang Jiang Ma Hu Wang Zeng He Oxidative stress response protects organisms from deleterious effects of reactive oxygen species (ROS), which can damage...
Medicine by Alexandros G. Sfakianakis
08:48
JCM, Vol. 8, Pages 1132: Catestatin in Acutely Decompensated Heart Failure Patients: Insights...
JCM, Vol. 8, Pages 1132: Catestatin in Acutely Decompensated Heart Failure Patients: Insights from the CATSTAT-HF StudyJCM, Vol. 8, Pages 1132: Catestatin in Acutely Decompensated Heart Failure Patients: Insights from the CATSTAT-HF Study Journal of Clinical Medicine doi: 10.3390/jcm8081132 Authors: Josip A. Borovac Duska Glavas Zora Susilovic Grabovac Daniela Supe Domic Domenico D'Amario Josko Bozic The role of catestatin (CST) in acutely decompensated heart failure (ADHF) and myocardial infarction...
Medicine by Alexandros G. Sfakianakis
08:47
Medicina, Vol. 55, Pages 421: Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by...
Medicina, Vol. 55, Pages 421: Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by Spin CoatingMedicina, Vol. 55, Pages 421: Advanced Drug-Eluting Poly (Vinyl Chloride) Surfaces Deposited by Spin Coating Medicina doi: 10.3390/medicina55080421 Authors: Oana Cristina Duta Maxim Maximov Roxana Trusca Anton Ficai Denisa Ficai Cornelia-Ioana Ilie Lia-Mara Ditu Ecaterina Andronescu Background and objectives: Medical devices such as catheters are used on a large scale to treat heart and cardiovascular...
Medicine by Alexandros G. Sfakianakis
08:47
Antibiotics, Vol. 8, Pages 107: Cytokine Expression Patterns and Single Nucleotide Polymorphisms...
Antibiotics, Vol. 8, Pages 107: Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic BorreliosisAntibiotics, Vol. 8, Pages 107: Cytokine Expression Patterns and Single Nucleotide Polymorphisms (SNPs) in Patients with Chronic Borreliosis Antibiotics doi: 10.3390/antibiotics8030107 Authors: Hein Sander Giryes Reinhardt Hoegel Schneider (1) Background: Genetically based hyperinflammation may play a role in pathogen defense. We here questioned whether alterations...
Medicine by Alexandros G. Sfakianakis
08:46
Brain Sciences, Vol. 9, Pages 184: Anoctamin 3: A Possible Link between Cluster Headache and Ca2+...
Brain Sciences, Vol. 9, Pages 184: Anoctamin 3: A Possible Link between Cluster Headache and Ca2+ SignalingBrain Sciences, Vol. 9, Pages 184: Anoctamin 3: A Possible Link between Cluster Headache and Ca2+ Signaling Brain Sciences doi: 10.3390/brainsci9080184 Authors: Ran Fourier Arafa Liesecke Sjöstrand Waldenlind Steinberg Belin Cluster headache is a severe primary headache characterized by extremely painful attacks of unilateral headache. Verapamil is commonly used as a prophylactic treatment with...
Medicine by Alexandros G. Sfakianakis
08:46
Cancers, Vol. 11, Pages 1082: Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization...
Cancers, Vol. 11, Pages 1082: Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional AnalysesCancers, Vol. 11, Pages 1082: Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses Cancers doi: 10.3390/cancers11081082 Authors: Hubert Gobbini Bendriss-Vermare Caux Valladeau-Guilemond The interaction between tumor cells and the immune system is considered to be a dynamic process. Dendritic cells (DCs) play a pivotal role in anti-tumor...
Medicine by Alexandros G. Sfakianakis
08:46
Minimally invasive treatment of pediatric head and neck dermoids: percutaneous drainage and radiofrequency...
Minimally invasive treatment of pediatric head and neck dermoids: percutaneous drainage and radiofrequency coblationAbstractBackgroundDermoids are common benign head and neck cysts in children containing a variety of different skin elements. Current standard treatment is surgical removal that sometimes requires extensive dissection to ensure complete resection and often leaves unwanted facial scarring. A minimally invasive treatment alternative should offer a similar rate of success with a decrease...
Medicine by Alexandros G. Sfakianakis
08:45
A novel percutaneous approach to retrieve an ingested extra-esophageal foreign body Abstract We report...
A novel percutaneous approach to retrieve an ingested extra-esophageal foreign bodyAbstractWe report a case of an 8-year-old boy who presented to our emergency department with progressive onset of dysphagia and odynophagia after eating barbecued steak that evening. Radiographs revealed a metal bristle from a barbecue brush at the level of the proximal esophagus. The otolaryngologist attempted to retrieve this bristle using flexible esophagoscopy, but unfortunately it pushed the bristle extra-esophageal....
Medicine by Alexandros G. Sfakianakis
08:44
Pediatric Radiology
Correction to: Plea for a standardized imaging approach to disorders of sex development in neonates: Consensus proposal from European Society of Paediatric Radiology task forceThe above article was published online with an incorrect author name.Physeal separation in pediatric osteomyelitisAbstractIn children, acute osteomyelitis, an infection of the bone, is most commonly hematogeneous in origin. Osteomyelitis is most often diagnosed with magnetic resonance imaging (MRI) and findings may include...
Medicine by Alexandros G. Sfakianakis
08:43
Management of arteriovenous malformation of the ear: A protocol for resection and reconstruction The...
Management of arteriovenous malformation of the ear: A protocol for resection and reconstructionThe Laryngoscope, EarlyView. The impact of social determinants of health on laryngotracheal stenosis development and outcomesThe Laryngoscope, EarlyView. Slide laryngotracheoplasty for congenital subglottic stenosis in newborns and infantsThe Laryngoscope, EarlyView. Quantifying the use of opioids in the immediate postoperative period after endoscopic sinus surgeryThe Laryngoscope, EarlyView. Is the gender...
Medicine by Alexandros G. Sfakianakis
08:43
Input and Soft-Tissue Vibration Characteristics during Sport-Specific Tasks Purpose To assess the influence...
Input and Soft-Tissue Vibration Characteristics during Sport-Specific TasksPurpose To assess the influence of sport-specific tasks on the characteristics of input and soft-tissue vibrations. Method Triaxial accelerometers were used to quantify the input (heel cup of the shoe) and soft-tissue vibrations of the gastrocnemius medialis and vastus lateralis muscles during seven sport-specific tasks performed by 10 healthy volunteers. A wavelet analysis was used to analyze the acceleration signals in the...
Medicine by Alexandros G. Sfakianakis
08:43
Obesity Surgery
Timing of Gestation After Laparoscopic Sleeve Gastrectomy (LSG): Does it Influence Obstetrical and Neonatal Outcomes of Pregnancies?Ivor Lewis Oesophagectomy for a Distal Adenocarcinoma of the Oesophagus 10 Years After Roux-en-Y Gastric Bypass (RYGB)Correction to: Longitudinal Impacts of Gastric Bypass Surgery on Pharmacodynamics and Pharmacokinetics of StatinsIn the original article the authors failed to include the following footnote:Christine Ren FieldingCorrection to: Incidence and Risk Factors...
Medicine by Alexandros G. Sfakianakis
08:42
Painful Myoclonus Triggered By Lateral Antebrachial Cutaneous Nerve Entrapment at Brachioradialis Muscle:...
Painful Myoclonus Triggered By Lateral Antebrachial Cutaneous Nerve Entrapment at Brachioradialis Muscle: A Case ReportCompression of the lateral antebrachial cutaneous nerve (LACN) is a rare clinical entrapment syndrome often overlooked as an initial etiology of pain 1. We present a case of an episodic upper extremity painful movement disorder (myoclonus) in a 16 year old female with a remote history of a surgically stabilized supracondylar humeral fracture who was later found to have entrapment...
Medicine by Alexandros G. Sfakianakis
08:41
LaryngologyOriginal ReportsSlide laryngotracheoplasty for congenital subglottic stenosis in newborns...
LaryngologyOriginal ReportsSlide laryngotracheoplasty for congenital subglottic stenosis in newborns and infantsLászló Rovó MD, PhD, Eszter Erdélyi MD, Zoltán Tóbiás MD, Péter Gál MD, Ilona Szegesdi MD, Balázs Sztanó MD, PhD, Kishore Sandu MD, Ádám Bach MD, PhDVersion of Record online: 27 July 2019Allergy/RhinologyOriginal ReportsQuantifying the use of opioids in the immediate postoperative period after endoscopic sinus surgeryIdo Badash BA, Christopher G. Lui BA, Kevin Hur MD, Joseph R. Acevedo...
Medicine by Alexandros G. Sfakianakis
08:40
Access to medicine and healthcare Jayasree K. Iyer celebrates the advances in healthcare access over...
Access to medicine and healthcare Jayasree K. Iyer celebrates the advances in healthcare access over the past decade and innovations still needed to reach everyone.Watch here
Medicine by Alexandros G. Sfakianakis
08:39
Preparing humans for space Christopher E. Mason presents the latest data from NASA's astronaut twin...
Preparing humans for space Christopher E. Mason presents the latest data from NASA's astronaut twin study and his vision for human expansion to Mars.Watch here
Medicine by Alexandros G. Sfakianakis
08:39



 Illumina Q2 Revenues Grow 1 PercentPublished on Jul 29, 2019 PerkinElmer Q2 Revenues Miss Wall Street...
 Illumina Q2 Revenues Grow 1 PercentPublished on Jul 29, 2019 PerkinElmer Q2 Revenues Miss Wall Street Estimate, Rise 3 PercentPublished on Jul 29, 2019 NeoGenomics Q2 Revenues Jump 50 PercentPublished on Jul 30, 2019 Waters Q2 Revenues Flat at $599MPublished on Jul 30, 2019 Meridian Bioscience Fiscal Q3 Revenues Dip 6 PercentPublished on Jul 30, 2019 NanoString, Mayo Clinic to Develop Novel Assays in High-Risk Breast Cancer and LeukemiaPublished on Jul 30, 2019 PredictImmune Closes £10M Series B...
Medicine by Alexandros G. Sfakianakis
08:23
Science, Medicine, and the Anesthesiologist Science, Medicine, and the Anesthesiologist FREE  PDF...
Science, Medicine, and the AnesthesiologistScience, Medicine, and the Anesthesiologist FREE PDFAnesthesiology August 2019, Vol.131, A11-A14. doi:10.1097/ALN.0000000000002895Infographics in AnesthesiologyBetter Care through Better Measurement: Toward Healthy Mothers and Newborns FREE PDFJonathan P. Wanderer; James P. RathmellTags: mothers, newbornAnesthesiology August 2019, Vol.131, A15. doi:10.1097/ALN.0000000000002889Anesthesiology CME ProgramInstructions for Obtaining Anesthesiology Continuing...
Medicine by Alexandros G. Sfakianakis
08:21
Dextromethorphan Effects on Hyperalgesia: Using the freeze-injury pain model in a randomized, double-blind,...
Dextromethorphan Effects on Hyperalgesia: Using the freeze-injury pain model in a randomized, double-blind, placebo-controlled crossover trial of 30-mg doses of oral dextromethorphan in 20 male volunteers, dextromethorphan was antihyperalgesic and reversed peripheral and central neuronal sensitization. Because dextromethorphan had no intrinsic antinociceptive effect in acute pain on healthy skin, N-methyl-d  aspartate receptors may need to be sensitized by pain for dextromethorphan to be effective. 
Medicine by Alexandros G. Sfakianakis
08:20
Encephalitis induced by immune checkpoint inhibitors in metastatic melanoma: a monocentric retrospective...
Encephalitis induced by immune checkpoint inhibitors in metastatic melanoma: a monocentric retrospective studyS. Galmiche, C. Lheure, N. Kramkimel, N. Franck, F. Boitier, N. Dupin, G. Turc, D. Psimaras, S. Aractingi, S. GuéganVersion of Record online: 26 July 2019 Open AccessOriginal ArticlesPatient‐assigned health utility values for controlled and uncontrolled pemphigus vulgaris and foliaceusK. Hajdu, V. Brodszky, P.F.M. Stalmeier, G. Ruzsa, B. Tamási, L. Gulácsi, M. Péntek, M. Sárdy, Z. Bata‐Csörgő, Á....
Medicine by Alexandros G. Sfakianakis
08:19
Tobramycin Concentration in the Lung: IVversus Nebulized: In a mechanically ventilated healthy large...
Tobramycin Concentration in the Lung: IVversus Nebulized: In a mechanically ventilated healthy large animal model, nebulized tobramycin produced higher peak lung interstitial space fluid concentrations, as well as higher initial epithelial lining fluid concentrations, with lower plasma concentrations than were observed after intravenous administration due to more extensive lung penetration. 
Medicine by Alexandros G. Sfakianakis
08:19
LifeSpan BioSciences, Invitae, Integrated DNA Technologies, and MorePublished on Jul 19, 2019Abcam Acquires...
LifeSpan BioSciences, Invitae, Integrated DNA Technologies, and MorePublished on Jul 19, 2019Abcam Acquires Knockout Cell Lines, Lysates Portfolio From EdiGenePublished on Jul 16, 2019Single-cell Sorting of T-Cells from a Heterogenous Population of Lyophilized CellsIn this whitepaper from NanoCellect learn about an easy-to-use system that can sort 300 cells per second without exerting stress on the cells or creating hazardous aerosols.Download it from GenomeWeb's White Paper Channel.
Medicine by Alexandros G. Sfakianakis
08:19
Silicone Suction Catheter Use in conjuction with Goco Elecrocautery Adenoid CuretteRetracts the soft...
Silicone Suction CatheterUse in conjuction with Goco Elecrocautery Adenoid CuretteRetracts the soft palate and evacuates smoke during electrosurgical adneoid surgeryInserts through the nostrils making the suction catheter completely hands freeRemove cauterized fumes and debris increasing surgical viewPulls smoke out of the way so it's not in your wayRemoves cancer causing cautery fumes away from the surgery siteSterile - individually packaged 
Medicine by Alexandros G. Sfakianakis
08:18
Electrocautery Adenoid Curette Decreased adenoid bleedingDecreased operative timeImproved recovery...
Electrocautery Adenoid CuretteDecreased adenoid bleedingDecreased operative timeImproved recovery timeWorks on footswitch or handswitch pencilsSterile - individually packaged9.5cm long with 3/32" shaft
Medicine by Alexandros G. Sfakianakis
08:18
Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor? Purpose of review...
Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?Purpose of review There is an inverse, graded relationship between worsening chronic kidney disease (CKD) and increasing cardiovascular risk independent of traditional cardiovascular risk factors. Increasing arterial stiffness is a powerful predictor of cardiovascular outcomes in CKD. Developing novel therapeutic strategies to reverse this process is an attractive concept. This review presents the results of a literature...
Medicine by Alexandros G. Sfakianakis
08:12
Intestinal lymphatic vessels and their role in chylomicron absorption and lipid homeostasis Purpose...
Intestinal lymphatic vessels and their role in chylomicron absorption and lipid homeostasisPurpose of review In this review, we describe novel findings related to intestinal lipid transport in lymphatic vessels. Recent findings Studies have shown that chylomicron entry to lacteals and lymph movement in intestinal lymphatic capillaries is an active process. Regulators of this intestinal chylomicron transport include among others the autonomous nervous system, transcription factors like PLAGL2, and...
Medicine by Alexandros G. Sfakianakis
08:12
Diagnosing invasive pulmonary aspergillosis in ICU patients: putting the puzzle together Purpose of...
Diagnosing invasive pulmonary aspergillosis in ICU patients: putting the puzzle togetherPurpose of review The approach to diagnose invasive pulmonary aspergillosis in the absence of lung biopsy in ICU patients is reviewed. This approach should be based on four pillars: mycology, medical imaging, underlying conditions, and acute disease expression. Recent findings Diagnosing invasive pulmonary aspergillosis in the absence of histopathologic evidence is a matter of probability weighting. Initiating...
Medicine by Alexandros G. Sfakianakis
08:12
American Journal of Orthodontics and Dentofacial Orthopedics
Directory: AAO Officers and OrganizationsPublication date: July 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 1Author(s):Cephalometry in orthodontics: 2D and 3DPublication date: July 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 1Author(s): Anne-Marie BollenJuly 2019:156(1)Publication date: July 2019Source: American Journal of Orthodontics and Dentofacial Orthopedics, Volume 156, Issue 1Author(s): Allen H....
Medicine by Alexandros G. Sfakianakis
08:11
GPER agonist G1 improves diastolic function and attenuates cardiac RAS activation in estrogen-deficient...
GPER agonist G1 improves diastolic function and attenuates cardiac RAS activation in estrogen-deficient hypertensive ratsThis study was aimed to clarify differences in how specific agonists of the three estrogen receptors (ERs) influence diastolic function and the renin angiotensin system (RAS) following ovariectomy (OVX) in twenty-four spontaneously hypertensive (SHR) females undergoing bilateral OVX at 12 weeks of age. Eight weeks postsurgery, rats were randomized (n=6/group) to receive equipotent,...
Medicine by Alexandros G. Sfakianakis
08:10
Anaesthesia & Intensive Care Medicine
Self-assessmentPublication date: Available online 13 July 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Vijayanand NadellaMedicolegal and social implications of practising in pain medicinePublication date: Available online 5 July 2019Source: Anaesthesia & Intensive Care MedicineAuthor(s): Lorraine de GrayAbstractPain is the most common reason for patients to see a doctor. Low social support and unemployment are common in such patients. Pain is the third leading cause for absence...
Medicine by Alexandros G. Sfakianakis
08:10
Oral Oncology - Supports open access
https://www.sciencedirect.com/journal/oral-oncology/articles-in-pressselect article Clinical validation of the Salivary HPV DNA assessment and its link to the locoregional disease burden in advanced HPV associated oropharyngeal cancerCorrespondenceNo accessClinical validation of the Salivary HPV DNA assessment and its link to the locoregional disease burden in advanced HPV associated oropharyngeal cancerRama Jayaraj, Chellan Kumarasamy, Madurantakam Royam Madhav, Sameep ShettyIn Press, Corrected...
Medicine by Alexandros G. Sfakianakis
08:09
Oral melanomas in HIV-positive patients: Report of two cases and review of the literature Thayná Melo...
Oral melanomas in HIV-positive patients: Report of two cases and review of the literatureThayná Melo de Lima Morais, Ciro Dantas Soares, Arthur Eric Costa Wanderley, Catarina Rodrigues Rosa de Oliveira, ... Sonia Maria Soares FerreiraIn Press, Corrected Proof, Available online 29 July 2019Purchase PDFArticle previewAbstractAbstractOral melanoma in HIV-positive patients is exceedingly rare, with only two cases reported in the literature published in English. Herein, we report two additional cases...
Medicine by Alexandros G. Sfakianakis
08:07
  Breast MRI: State of the Art    Indications for breast MRI are consolidating; MRI for screening...
 Breast MRI: State of the Art  Indications for breast MRI are consolidating; MRI for screening leads to earlier cancer detection in virtually all evaluated populations; in the hands of experienced teams, MRI allows for improvement of surgical practice, reducing the number of re-excisions while preventing unnecessary mastectomies; and MRI allows for patient selection for neoadjuvant chemotherapy and is the technique of choice to support modification of therapeutic agents and for presurgical assessment...
Medicine by Alexandros G. Sfakianakis
08:06
  Smoking Significantly Impacts Persistence Rates in Embolized Pulmonary Arteriovenous Malformations...
 Smoking Significantly Impacts Persistence Rates in Embolized Pulmonary Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia Patients with hereditary hemorrhagic telangiectasia and active tobacco use have higher rates of pulmonary arteriovenous malformation persistence after percutaneous embolization.    Mustafa M. Haddad, Emily C. Bendel...Sanjay MisraEditorial: Persistence of Pulmonary Arteriovenous Malformation after Embolization: Another Reason to Quit SmokingScott...
Medicine by Alexandros G. Sfakianakis
08:05
  CT-defined Visceral Pleural Invasion in T1 Lung Adenocarcinoma: Lack of Relationship to Disease-Free...
 CT-defined Visceral Pleural Invasion in T1 Lung Adenocarcinoma: Lack of Relationship to Disease-Free Survival CT features of visceral pleural invasion are not independent prognostic factors in clinical T1 lung adenocarcinomas; upstaging from clinical T1 to T2 for lung cancers that contact the pleura or exhibit pleural tags on CT scans is not an evidence-based practice.     Hyungjin Kim, Jin Mo Goo...Chang Min ParkEditorial: Using CT to Evaluate Visceral Pleural Invasion: Caution Is AdvisedMizuki...
Medicine by Alexandros G. Sfakianakis
08:05
  Cardiac MRI and Texture Analysis of Myocardial T1 and T2 Maps in Myocarditis with Acute versus...
 Cardiac MRI and Texture Analysis of Myocardial T1 and T2 Maps in Myocarditis with Acute versus Chronic Symptoms of Heart Failure Texture analysis of MRI T1 and T2 maps of the myocardium delivers quantitative imaging parameters for the challenging diagnosis of acute or chronic heart failure–like myocarditis and shows superior diagnostic performance compared with Lake Louise criteria or conventional parametric mapping.     Bettina Baessler, Christian Luecke...Philipp Lurz Editorial: Diagnosis of Myocarditis...
Medicine by Alexandros G. Sfakianakis
08:05
  Iodine-based Dual-Energy CT of Traumatic Hemorrhagic Contusions: Relationship to In-Hospital...
 Iodine-based Dual-Energy CT of Traumatic Hemorrhagic Contusions: Relationship to In-Hospital Mortality and Short-term Outcome Quantitative iodine-based parameters derived from dual-energy CT are used to measure both the volume of penumbra that manifests as a nonhemorrhagic component of contusion and the magnitude of capillary disruption in the epicenter and penumbra while also enabling prediction of in-hospital mortality and short-term outcome.     Uttam K. Bodanapally, Kathirkamanathan Shanmuganathan...Thorsten...
Medicine by Alexandros G. Sfakianakis
08:05
 Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression SignaturePublished...
 Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression SignaturePublished on Jul 30, 2019 Hazelden Betty Ford Foundation, Mayo Clinic to Study Pharmacogenomics of Alcoholism TreatmentPublished on Jul 30, 2019 Curetis Inks European Distribution Deals for MDx ProductsPublished on Jul 30, 2019Featured in Depth Illumina Says Population Sequencing, DTC Will Continue to Grow in the Long TermPublished on Jul 30, 2019 Exact Sciences Touts Advantages of Genomic Health Acquisition...
Medicine by Alexandros G. Sfakianakis
08:04
Learners and Luddites in the Twenty-first Century: Bringing Evidence-based Education to Anesthesiology...
Learners and Luddites in the Twenty-first Century: Bringing Evidence-based Education to AnesthesiologySusan M. Martinelli, M.D., F.A.S.A.; Robert S. Isaak, D.O., F.A.S.A.; Randall M. Schell, M.D., M.A.C.M.; John D. Mitchell, M.D.; Matthew D. McEvoy, M.D.; Fei Chen, Ph.D.Anesthesiology Published online July 29, 2019. doi:10.1097/ALN.0000000000002827Images in AnesthesiologySpinal Epidural Hematoma after Interlaminar Cervical Epidural Steroid InjectionRatan K. Banik, M.D., Ph.D.; Clark C. Chen Chen,...
Medicine by Alexandros G. Sfakianakis
08:03
Unlearning Cardiac Arrest: What You Thought You Knew Presented by ZOLL The Rialto Fire Department changed...
Unlearning Cardiac Arrest: What You Thought You KnewPresented by ZOLLThe Rialto Fire Department changed the way members approach cardiac arrest and it has resulted in a large jump in ROSC rates and an 83% Utstein rate. Presented by Fire Chief Sean Grayson and EMS Chief Joe Powell.
Medicine by Alexandros G. Sfakianakis
08:02
Patient Lifting and Moving: Whose Job Is It? Colin Zimmerman BS, NRP, Madison Werner, BS, NRP, Kanya...
Patient Lifting and Moving: Whose Job Is It?Colin Zimmerman BS, NRP, Madison Werner, BS, NRP, Kanya Dayananth, BS, NRP, Ross Manganaro, BS, NRP, Walt A. Stoy, PhD, EMT-PThe lack of proficiency in lifting and moving patients often originates in EMS education. This article reviews the challenges EMS educators face when teaching these skills and offers recommendations for the future.
Medicine by Alexandros G. Sfakianakis
08:02
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
MDPIMolbank, Vol. 2019, Article M1075: N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamideMolbank, Vol. 2019, Article M1075: N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide Molbank doi: 10.3390/M1075 Authors: Hamad H. Al Mamari Nasser Al Awaimri Yousuf Al Lawati The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by...
Medicine by Alexandros G. Sfakianakis
Tue Jul 30, 2019 09:56

Pediatric Radiology

Correction to: Plea for a standardized imaging approach to disorders of sex development in neonates: Consensus proposal from European Society of Paediatric Radiology task force

The above article was published online with an incorrect author name.



Physeal separation in pediatric osteomyelitis

Abstract

In children, acute osteomyelitis, an infection of the bone, is most commonly hematogeneous in origin. Osteomyelitis is most often diagnosed with magnetic resonance imaging (MRI) and findings may include marrow signal changes on T1 and T2, with abnormal enhancement after gadolinium. Imaging helps detect any associated intraosseous or subperiosteal abscesses, which may require orthopedic drainage. In this pictorial essay, we demonstrate the association of acute pediatric osteomyelitis with physeal separation, resulting in what may be confused for simple trauma, although there was no known history of trauma in any of the cases we researched. All of the cases had a large subperiosteal fluid collection with marked separation of the epiphysis from the metaphysis. It is important to recognize this potential association in osteomyelitis, as it is readily visible by radiographs and may lead to diagnostic uncertainty.



A portrait of pediatric leadership: Dr. Benjamin Spock


A novel percutaneous approach to retrieve an ingested extra-esophageal foreign body

Abstract

We report a case of an 8-year-old boy who presented to our emergency department with progressive onset of dysphagia and odynophagia after eating barbecued steak that evening. Radiographs revealed a metal bristle from a barbecue brush at the level of the proximal esophagus. The otolaryngologist attempted to retrieve this bristle using flexible esophagoscopy, but unfortunately it pushed the bristle extra-esophageal. In order to avoid major open surgery with associated morbidity, a novel percutaneous image-guided minimally invasive percutaneous approach was used to successfully retrieve the bristle.



Hermes


Plea for a standardized imaging approach to disorders of sex development in neonates: consensus proposal from European Society of Paediatric Radiology task force

Abstract

This consensus article elaborated by the European Society for Paediatric Radiology task force on gastrointestinal and genitourinary imaging is intended to standardize the imaging approach in newborns with disorders of sex development. These newborns represent a difficult and stressful situation necessitating a multidisciplinary team approach. Imaging plays an important role in the work-up but needs to be optimized and customized to the patient. Ultrasound plays the central role in assessing the genital anatomy. The examination must be conducted in a detailed and systematic way. It must include transabdominal and transperineal approaches with adapted high-resolution transducers. The pelvic cavity, the genital folds, the inguinal areas and the adrenals must be evaluated as well as the rest of the abdominal cavity. A reporting template is proposed. The indications of magnetic resonance imaging and cysto- and genitography are discussed as well as they may provide additional information. Imaging findings must be reported cautiously using neutral wording as much as possible.



Pediatric postmortem computed tomography: initial experience at a children's hospital in the United States

Abstract

Postmortem CT might provide valuable information in determining the cause of death and understanding disease processes, particularly when combined with traditional autopsy. Pediatric applications of postmortem imaging represent a new and rapidly growing field. We describe our experience in establishing a pediatric postmortem CT program and present a discussion of the distinct challenges in developing this type of program in the United States of America, where forensic practice varies from other countries. We give a brief overview of recent literature along with the common imaging findings on postmortem CT that can simulate antemortem pathology.



Minimally invasive treatment of pediatric head and neck dermoids: percutaneous drainage and radiofrequency coblation

Abstract

Background

Dermoids are common benign head and neck cysts in children containing a variety of different skin elements. Current standard treatment is surgical removal that sometimes requires extensive dissection to ensure complete resection and often leaves unwanted facial scarring. A minimally invasive treatment alternative should offer a similar rate of success with a decrease in operative complexity, recovery time and postoperative scarring.

Objective

To assess the outcomes of our minimally invasive percutaneous treatment of head and neck dermoids, we reviewed our 9-year interventional radiology (IR) department experience.

Materials and methods

The medical records, imaging and procedural details were reviewed from a cohort of pediatric patients with dermoids treated in our IR department from January 2009 through February 2018. Patients in the study underwent ultrasound (US)-guided cyst puncture, 3% Sotradecol (sodium tetradecyl sulfate [STS]) emulsification of the thick cyst contents allowing complete drainage, and radiofrequency coblation of the cyst wall.

Results

In this retrospective study, we report on 22 dermoids in 21 patients. The average patient age was 3 years. Twenty-one of the 22 dermoids were successfully treated for an overall success rate of 95%. Four intraosseous dermoids were successfully treated using computed tomography (CT) guidance instead of, or in addition to, US. Average follow-up time was 22 months.

Conclusion

The combination of percutaneous cyst drainage using STS as an emulsifying agent followed by radiofrequency coblation is a safe, effective, minimally invasive treatment for pediatric patients with head and neck dermoids.



Proximal radius fractures in children: evaluation of associated elbow fractures

Abstract

Background

Additional fractures occur in association with proximal radius fractures, but the extent of these secondary injuries has not been systematically assessed.

Objective

To ascertain the frequency and nature of additional fractures associated with proximal radius injuries in a large pediatric cohort.

Materials and methods

Radiographs meeting search criteria for proximal radius fracture during a 5-year period were reviewed. Fracture characteristics and the coexistence of additional elbow fractures were recorded and analyzed. The retrospective review was compared with initial interpretation and a blinded review by two pediatric musculoskeletal radiologists.

Results

Four hundred ninety-four proximal radius fractures were included. The radial neck was the most common fracture site (89%). Neck fractures occurred in younger patients (mean: 7.3 years) than head fractures (mean: 13.3 years) (P<0.001). Additional elbow fractures occurred in 39%, most commonly at the olecranon (22%). Additional fractures occurred in younger patients (mean: 7.2 years) than isolated proximal radius fractures (mean: 8.5 years) (P<0.001). Elbow joint effusion and complete or displaced radius fractures were each associated with additional elbow fractures (P<0.001). When compared with initial interpretation, 25% of additional fractures were not identified on initial radiographs, of which 44% were occult retrospectively. Fracture identification demonstrated excellent inter-reader reliability (interclass correlation coefficient [ICC]: 0.88, 0.94), but joint effusion interobserver agreement was only fair (ICC: 0.52, 0.41).

Conclusion

Proximal radius fractures in children often occur in association with other elbow fractures, most commonly involving the olecranon. Enhanced awareness of these fracture patterns, especially in the setting of joint effusion or complete and displaced radius fractures, may improve detection to guide appropriate management.



Clinico-radiologic features of pleuroparenchymal fibroelastosis in children

Abstract

Background

Pleuroparenchymal fibroelastosis (PPFE) may be underdiagnosed clinically and radiographically in children with a remote history of cancer, leading to a delay in care and unnecessary lung biopsies.

Objective

To describe the characteristic clinical and radiologic findings of PPFE in a cohort of children to facilitate recognition and noninvasive diagnosis.

Materials and methods

Clinical presentation, history of chemotherapy or radiation therapy, lung or bone marrow transplantation, and lung function testing and outcome were retrospectively extracted from the electronic medical records of eight children treated at our institution's pulmonary medicine clinic with histopathology confirmation of PPFE from 2008 to 2018. Two pediatric radiologists evaluated the chest imaging studies for the presence or absence of published radiologic findings of PPFE in adults, including platythorax, pneumothorax, upper lobe predominant pleural and septal thickening, and bronchiectasis. Platythorax indices were calculated from the normal chest CT exams of eight age- and gender-matched individuals obtained via the radiology search engine.

Results

The mean presentation age was 12.9 years (range: 7–16 years). Seven of the eight had a history of chemotherapy and radiation therapy for cancer. Three of the eight had undergone bone marrow transplantation and none had undergone lung transplantation. The mean time between chemotherapy, radiation therapy, and/or bone marrow transplantation and the presentation of PPFE was 8.4 years (range: 5.6–12.1 years). Most of the patients presented with dyspnea (63%), cough (50%) and/or pneumothorax (38%). The mean percentage of predicted FEV1 (forced expiratory volume in one second) was 14.1 (range: 7.7–27.5). All eight patients demonstrated platythorax, bronchiectasis, pleural and septal thickening (upper lobes in four, upper and lower lobes in four) and six had pneumothorax. Five underwent lung biopsies, four of whom developed pneumothoraces.

Conclusion

Clinical and radiologic findings of pediatric PPFE are similar to those in adults, although a majority of the former have a history of treated cancer. Clinical presentation of restrictive lung disease, dyspnea, cough or spontaneous pneumothorax years after treatment for childhood cancer combined with platythorax, upper lobe pleural and septal thickening and traction bronchiectasis on chest CT establishes a presumptive diagnosis of PPFE.



Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480