Medicine by Sfakianakis G. Alexandros

Tuesday, November 27, 2018

Transnasal vocal fold augmentation.

Transnasal vocal fold augmentation.

Ear Nose Throat J. 2018 Jan-Feb;97(1-2):E56

Authors: Knabel MJ, Bock JM

PMID: 29493735 [PubMed - indexed for MEDLINE]

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Characteristics of speech production in patients with T1 glottic cancer who underwent laser cordectomy or radiotherapy.

Characteristics of speech production in patients with T1 glottic cancer who underwent laser cordectomy or radiotherapy.

Logoped Phoniatr Vocol. 2018 Oct;43(3):120-128

Authors: Hong YT, Park MJ, Hong KH

Abstract
PURPOSE: Laser cordectomy (LC) or radiotherapy (RT) is often recommended in the early stage of laryngeal cancer. We conducted perceptual and acoustic analysis to compare sustained vowel and stop consonants since there is no article evaluating both the sustained vowel and stop consonants. Eventually, we might determine which management is superior in terms of speech production.
SUBJECTS AND METHODS: A total of 28 patients who underwent LC and RT for early T1 glottic cancer were selected. The sustained vowel /a/ and bilabial stop consonants were used to assess the perceptual scores. The fundamental frequency (Fo), jitter, shimmer and noise-to-harmonic ratio (NHR) levels for sustained vowels were evaluated. Voice onset time (VOT), vowel duration (VD) and closure duration of the bilabial plosives were analyzed. A receiver operating characteristic curve analysis was used to evaluate significant results statistically.
RESULTS: The GRBAS and discrimination scores were not significantly different between two groups. Fo and jitter were significantly higher in the LC than RT. The cut-off value was statistically higher in the LC group and statistically lower in the RT group. The VOT was significantly longer in the LC than RT. The cut-off value of the /pipida/ VOT was statistically longer in the LC group and statistically shorter in the RT group.
CONCLUSIONS: The differences may have been due to muscular fibrosis after RT. Movements of vocal cords with fibrosis were sluggish, when impulsion developed to pronounce the initial /p/ sound, so the VOT was shortened and the VD was longer after RT.

PMID: 28975857 [PubMed - indexed for MEDLINE]

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Vocal fold hemorrhage into a physiologic sulcus.

Vocal fold hemorrhage into a physiologic sulcus.

Ear Nose Throat J. 2017 Jun;96(6):198-199

Authors: Benito DA, Romak JJ, Sataloff RT

PMID: 28636727 [PubMed - indexed for MEDLINE]

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Atypical presentation of vocal fold granulomas.

Atypical presentation of vocal fold granulomas.

Ear Nose Throat J. 2017 Apr-May;96(4-5):E45-E46

Authors: Patel RB, Jaworek A, Sataloff RT

PMID: 28489246 [PubMed - indexed for MEDLINE]

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Linear IgA dermatosis limited to the mucosal membranes as a rare cause of dysphagia.

Linear IgA dermatosis limited to the mucosal membranes as a rare cause of dysphagia.

Ear Nose Throat J. 2017 Apr-May;96(4-5):162-163

Authors: Bones VM, Madden LL

PMID: 28489233 [PubMed - indexed for MEDLINE]

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Operative technique: Lateral neck dissection.

Operative technique: Lateral neck dissection.

Head Neck. 2018 Nov 26;:

Authors: Pagedar NA, Fowlkes JW, Sheffield AM

PMID: 30475416 [PubMed - as supplied by publisher]

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Massive aneurysmal bone cyst of the skull base treated with denosumab.

Massive aneurysmal bone cyst of the skull base treated with denosumab.

Head Neck. 2018 Nov 26;:

Authors: Asi KW, Abdelmeguid A, Bell D, Hanna EY

Abstract
BACKGROUND: Aneurysmal bone cysts are rare, benign expansile tumors most commonly involving long bones and vertebrae in patients younger than age 20. Skull base involvement is rare. Aneurysmal bone cysts shares radiological and histological features with other bone tumors, posing a diagnostic challenge.
METHODS/RESULTS: We report the case of a 32-year-old man who presented with facial pain, epistaxis, and cranial neuropathies secondary to a massive tumor of the maxillary sinus and anterior skull base. The tumor was originally misdiagnosed as osteosarcoma. However, genomic analysis revealed a rearrangement in the USP6 gene, elucidating a diagnosis of primary aneurysmal bone cysts. The patient was treated with denosumab. Within 5 months, the patient was asymptomatic with CT showing ossification of the tumor.
CONCLUSIONS: This case highlights (1) the utility of genomic analysis in aggressive bone tumors when the diagnosis is unclear and (2) the effectiveness of denosumab as a treatment for aneurysmal bone cysts when surgical resection is unfavorable.

PMID: 30475414 [PubMed - as supplied by publisher]

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